Design and development strategies of polymer materials for drug and gene delivery applications☆

2008 ◽  
Vol 60 (9) ◽  
pp. 957-957 ◽  
Author(s):  
D OUPICKY
Keyword(s):  
Gene Delivery ◽  
Development Strategies ◽  
Polymer Materials ◽  
Design And Development ◽  
Drug And Gene Delivery

scholarly journals Computing Zagreb and Randić Indices of PEG-Cored Dendrimers Used for Drug and Gene Delivery

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Thayamathy Pio Jude ◽  
Elango Panchadcharam ◽  
Koneswaran Masilamani
Keyword(s):  
Gene Delivery ◽  
Drug Design ◽  
Topological Indices ◽  
Randić Index ◽  
Molecular Topology ◽  
Design And Development ◽  
Randic Index ◽  
Zagreb Indices ◽  
Chemical Structures ◽  
Drug And Gene Delivery

Zagreb and Randić indices are the most commonly used degree-based topological indices in the study of drug design and development. In molecular topology, M-polynomials are also used to calculate the degree-based topological indices of chemical structures. In this paper, we derive the M-polynomials for the PEG-cored PAMAM, carbosilane, and poly (lysine) dendrimers and calculate their first, second, and second modified Zagreb indices and the Randić index.

Graphene and Graphene-Based Materials in Biomedical Applications

2019 ◽  
Vol 26 (38) ◽  
pp. 6834-6850 ◽  
Author(s):  
Mohammad Omaish Ansari ◽  
Kalamegam Gauthaman ◽  
Abdurahman Essa ◽  
Sidi A. Bencherif ◽  
Adnan Memic
Keyword(s):  
Tissue Engineering ◽  
Thermal Properties ◽  
Gene Delivery ◽  
Regenerative Medicine ◽  
Biomedical Research ◽  
Biomedical Applications ◽  
Biomedical Application ◽  
Two Dimensional ◽  
Drug And Gene Delivery ◽  
Biomedical Fields

: Nanobiotechnology has huge potential in the field of regenerative medicine. One of the main drivers has been the development of novel nanomaterials. One developing class of materials is graphene and its derivatives recognized for their novel properties present on the nanoscale. In particular, graphene and graphene-based nanomaterials have been shown to have excellent electrical, mechanical, optical and thermal properties. Due to these unique properties coupled with the ability to tune their biocompatibility, these nanomaterials have been propelled for various applications. Most recently, these two-dimensional nanomaterials have been widely recognized for their utility in biomedical research. In this review, a brief overview of the strategies to synthesize graphene and its derivatives are discussed. Next, the biocompatibility profile of these nanomaterials as a precursor to their biomedical application is reviewed. Finally, recent applications of graphene-based nanomaterials in various biomedical fields including tissue engineering, drug and gene delivery, biosensing and bioimaging as well as other biorelated studies are highlighted.

Redox-Sensitive Smart Nanosystems for Drug and Gene Delivery

2016 ◽  
Vol 20 (28) ◽  
pp. 2949-2959 ◽  
Author(s):  
Mahdi Karimi ◽  
Seyed Basri ◽  
Manouchehr Vossoughi ◽  
Parvin Pakchin ◽  
Hamed Mirshekari ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Drug And Gene Delivery

scholarly journals Recent Advances of Nanotechnology-Facilitated Bacteria-Based Drug and Gene Delivery Systems for Cancer Treatment

Pharmaceutics ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 940
Author(s):  
Chaojie Zhu ◽  
Zhiheng Ji ◽  
Junkai Ma ◽  
Zhijie Ding ◽  
Jie Shen ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Cancer Treatment ◽  
Delivery Systems ◽  
Cancer Targeting ◽  
Cancer Treatments ◽  
Recent Advances ◽  
Therapeutic Mechanisms ◽  
Bacterial Therapy ◽  
Targeting Ability ◽  
Drug And Gene Delivery

Cancer is one of the most devastating and ubiquitous human diseases. Conventional therapies like chemotherapy and radiotherapy are the most widely used cancer treatments. Despite the notable therapeutic improvements that these measures achieve, disappointing therapeutic outcome and cancer reoccurrence commonly following these therapies demonstrate the need for better alternatives. Among them, bacterial therapy has proven to be effective in its intrinsic cancer targeting ability and various therapeutic mechanisms that can be further bolstered by nanotechnology. In this review, we will discuss recent advances of nanotechnology-facilitated bacteria-based drug and gene delivery systems in cancer treatment. Therapeutic mechanisms of these hybrid nanoformulations are highlighted to provide an up-to-date understanding of this emerging field.

Development of self-assembling peptide nanovesicle with bilayers for enhanced EGFR-targeted drug and gene delivery

Biomaterials ◽  
2016 ◽  
Vol 82 ◽  
pp. 194-207 ◽  
Author(s):  
Xiaofei Liang ◽  
Bizhi Shi ◽  
Kai Wang ◽  
Mingliang Fan ◽  
Dejin Jiao ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Self Assembling ◽  
Targeted Drug ◽  
Drug And Gene Delivery

PEGylated PAMAM dendrimers: Enhancing efficacy and mitigating toxicity for effective anticancer drug and gene delivery

2016 ◽  
Vol 43 ◽  
pp. 14-29 ◽  
Author(s):  
Duy Luong ◽  
Prashant Kesharwani ◽  
Rahul Deshmukh ◽  
Mohd Cairul Iqbal Mohd Amin ◽  
Umesh Gupta ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Anticancer Drug ◽  
Pamam Dendrimers ◽  
Drug And Gene Delivery

scholarly journals Microbubbles in ultrasound-triggered drug and gene delivery

2008 ◽  
Vol 60 (10) ◽  
pp. 1153-1166 ◽  
Author(s):  
Sophie Hernot ◽  
Alexander L. Klibanov
Keyword(s):  
Gene Delivery ◽  
Drug And Gene Delivery
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