Transplanting stem cells: Potential targets for immune attack. Modulating the immune response against embryonic stem cell transplantation

2005 ◽  
Vol 57 (13) ◽  
pp. 1944-1969 ◽  
Author(s):  
A BOYD ◽  
Y HIGASHI ◽  
K WOOD
Keyword(s):  
Stem Cells ◽  
Immune Response ◽  
Stem Cell ◽  
Stem Cell Transplantation ◽  
Embryonic Stem Cell ◽  
Cell Transplantation ◽  
Embryonic Stem ◽  
Immune Attack

Stem Cell Transplantation: A Promising Therapy for Spinal Cord Injury

2020 ◽  
Vol 15 (4) ◽  
pp. 321-331 ◽  
Author(s):  
Zhe Gong ◽  
Kaishun Xia ◽  
Ankai Xu ◽  
Chao Yu ◽  
Chenggui Wang ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Stem Cells ◽  
Spinal Cord Injury ◽  
Stem Cell ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Therapeutic Potential ◽  
Embryonic Stem ◽  
Current Status ◽  
Cord Injury

Spinal Cord Injury (SCI) causes irreversible functional loss of the affected population. The incidence of SCI keeps increasing, resulting in huge burden on the society. The pathogenesis of SCI involves neuron death and exotic reaction, which could impede neuron regeneration. In clinic, the limited regenerative capacity of endogenous cells after SCI is a major problem. Recent studies have demonstrated that a variety of stem cells such as induced Pluripotent Stem Cells (iPSCs), Embryonic Stem Cells (ESCs), Mesenchymal Stem Cells (MSCs) and Neural Progenitor Cells (NPCs) /Neural Stem Cells (NSCs) have therapeutic potential for SCI. However, the efficacy and safety of these stem cellbased therapy for SCI remain controversial. In this review, we introduce the pathogenesis of SCI, summarize the current status of the application of these stem cells in SCI repair, and discuss possible mechanisms responsible for functional recovery of SCI after stem cell transplantation. Finally, we highlight several areas for further exploitation of stem cells as a promising regenerative therapy of SCI.

Embryonic Stem Cell Transplantation

BioDrugs ◽  
2008 ◽  
Vol 22 (6) ◽  
pp. 361-374 ◽  
Author(s):  
Feixiong Zhang ◽  
Kishore B S Pasumarthi
Keyword(s):  
Stem Cell ◽  
Stem Cell Transplantation ◽  
Embryonic Stem Cell ◽  
Cell Transplantation ◽  
Embryonic Stem

scholarly journals Human embryonic stem cell transplantation to repair the infarcted myocardium

Heart ◽  
2007 ◽  
Vol 93 (10) ◽  
pp. 1278-1284 ◽  
Author(s):  
J. Leor ◽  
S. Gerecht ◽  
S. Cohen ◽  
L. Miller ◽  
R. Holbova ◽  
...  
Keyword(s):  
Stem Cell ◽  
Stem Cell Transplantation ◽  
Embryonic Stem Cell ◽  
Cell Transplantation ◽  
Human Embryonic Stem Cell ◽  
Embryonic Stem ◽  
Infarcted Myocardium
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