Magnetic Marker Monitoring: An application of biomagnetic measurement instrumentation and principles for the determination of the gastrointestinal behavior of magnetically marked solid dosage forms

2005 ◽  
Vol 57 (8) ◽  
pp. 1210-1222 ◽  
Author(s):  
W WEITSCHIES ◽  
O KOSCH ◽  
H MONNIKES ◽  
L TRAHMS
Keyword(s):  
Dosage Forms ◽  
Solid Dosage Forms ◽  
Solid Dosage ◽  
Magnetic Marker ◽  
Magnetic Marker Monitoring

Determination of Aspirin and Salicylic Acid by Reverse-Phase Liquid Chromatography

1987 ◽  
Vol 70 (6) ◽  
pp. 964-966
Author(s):  
Dorothy R Heidemann ◽  
Edward S Schulenberg ◽  
William H Smith
Keyword(s):  
Salicylic Acid ◽  
Dosage Forms ◽  
Solid Dosage Forms ◽  
Reverse Phase ◽  
Solid Dosage ◽  
Reverse Phase Liquid Chromatography ◽  
Sample Extraction ◽  
Phase Liquid ◽  
Phase Column

Abstract Buffered solid dosage forms containing aspirin, magnesium hydroxide, and aluminum hydroxide are blended with acidic ethanol to extract the aspirin and salicylic acid rapidly. The resulting preparation is then immediately injected onto a 4.6 mm x 3 cm 5 (im reverse-phase column. Aspirin and free salicylic acid are determined simultaneously. The run time is <2 min. The total time from the initiation of sample extraction to completion of the separation is <5 min.

Novel First Order Derivative UV Spectrophotometric Method for the Determination of Glimepiride in Solid Dosage Forms

2018 ◽  
Vol 8 (3) ◽  
Author(s):  
Santosh Karajgi . ◽  
Sunayana Mali ◽  
Ramaling Kotnal
Keyword(s):  
Dosage Forms ◽  
Order Derivative ◽  
Simultaneous Estimation ◽  
Drug Form ◽  
Solid Dosage Forms ◽  
First Order ◽  
Solid Dosage ◽  
Tablet Dosage ◽  
Guide Lines

Objective: An easy, perfect, specific and exact process has been studied for the simultaneous estimation of Glimepiride pure drug form as well as tablet dosage forms. Methods: A UV method for quantitative evaluation of Glimepiride by first order derivative peak detect method for determination in bulk as well as tablet dosage form is reported as there was a need to expand novel methods to analyze the drug. Results: Glimepiride has absorbance first derivative maxima at 225 nm in Methanol. Glimepiride follows Beer’s law in concentration range of 5-25µg/ml. The outcomes of the study were validated statistically and recovery studies were performed as per ICH guide lines. Conclusion: Thus the projected method can be applied competently for the estimation of Glimepiride in regular analysis in its dosage forms.

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