Immunity in response to particulate antigen-delivery systems

2005 ◽  
Vol 57 (3) ◽  
pp. 333-355 ◽  
Author(s):  
T STORNI ◽  
T KUNDIG ◽  
G SENTI ◽  
P JOHANSEN
Keyword(s):  
Delivery Systems ◽  
Antigen Delivery ◽  
Particulate Antigen ◽  
Antigen Delivery Systems

Administration routes affect the quality of immune responses: A cross-sectional evaluation of particulate antigen-delivery systems

2010 ◽  
Vol 147 (3) ◽  
pp. 342-349 ◽  
Author(s):  
Deepa Mohanan ◽  
Bram Slütter ◽  
Malou Henriksen-Lacey ◽  
Wim Jiskoot ◽  
Joke A. Bouwstra ◽  
...  
Keyword(s):  
Immune Responses ◽  
Delivery Systems ◽  
Antigen Delivery ◽  
Cross Sectional ◽  
Administration Routes ◽  
Particulate Antigen ◽  
Antigen Delivery Systems

scholarly journals Implantable vaccines: a solution for immune system manipulation to any antigenic stimulus

2020 ◽  
Vol 4 (4) ◽  
pp. 5-11
Author(s):  
Ioanna Zerva ◽  
Vasileia Pateraki ◽  
Irene Athanassakis
Keyword(s):  
Immune Response ◽  
Ex Vivo ◽  
Great Majority ◽  
Delivery Systems ◽  
Antigen Delivery ◽  
Immune Responsiveness ◽  
Antigenic Stimulus ◽  
Human Pathology ◽  
Check Points ◽  
Antigen Delivery Systems

Effective and side-effect-free vaccines are still difficult tasks to achieve for a great majority of antigenic stimuli. Pathogen manipulation to abort infectivity and antigen delivery to ensure immune responsiveness are the major components vaccine technology tries to resolve. However, the development of an immune response is still a complicated matter, lies on hundreds of parameters and any effort towards activation can easily lead to adverse effects, making immunotherapy very difficult to control. The present review attempts to highlight the major parameters affecting immune responsiveness and show that vaccine technology, except from pathogen manipulation and the development of antigen delivery systems, requires attention to additional check-points. Analyzing the recently described personalized implantable vaccine technology, it becomes obvious that the nature of each antigenic stimulus dictates different responsiveness to the organism, which discourages the use of universal adjuvant and antigen-delivery systems. On the contrary, the ex vivo tuning of the immune response proposed by the implantable vaccine technology, allows controllable amendment of the response. The development of personalized technologies is expected to provide valuable tools for the management of human pathology.

Antigen Delivery Systems I: Nonliving Microparticles, Liposomes, and Immune Stimulating Complexes (ISCOMs)

2005 ◽  
pp. 987-1007 ◽  
Author(s):  
Suzanne M. Michalek ◽  
Derek T. O'Hagan ◽  
Noel K. Childers ◽  
Albert D.M.E. Osterhaus ◽  
Guus F. Rimmelzwaan
Keyword(s):  
Delivery Systems ◽  
Antigen Delivery ◽  
Antigen Delivery Systems

Lipid-based antigen delivery systems

2016 ◽  
Vol 46 (4) ◽  
pp. 295-304 ◽  
Author(s):  
Joo Yeon Park ◽  
Mi-Gyeong Kim ◽  
Gayong Shim ◽  
Yu-Kyoung Oh
Keyword(s):  
Delivery Systems ◽  
Antigen Delivery ◽  
Antigen Delivery Systems
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