Evaluation of smokers with and without asthma in terms of smoking cessation outcome, nicotine withdrawal symptoms, and craving: Findings from a self-guided quit attempt

2016 ◽  
Vol 63 ◽  
pp. 149-154 ◽  
Author(s):  
Alison C. McLeish ◽  
Samantha G. Farris ◽  
Adrienne L. Johnson ◽  
Jonathan A. Bernstein ◽  
Michael J. Zvolensky
Keyword(s):  
Smoking Cessation ◽  
Nicotine Withdrawal ◽  
Withdrawal Symptoms ◽  
Quit Attempt ◽  
Smoking Cessation Outcome

Subjective social status is indirectly associated with short-term smoking cessation through nicotine withdrawal symptoms

2020 ◽  
pp. 135910532091143
Author(s):  
Adam C Alexander ◽  
Oluwakemi Olurotimi ◽  
Emily T Hébert ◽  
Chaelin Karen Ra ◽  
Michael S Businelle ◽  
...  
Keyword(s):  
Smoking Cessation ◽  
Social Status ◽  
Subjective Social Status ◽  
Nicotine Withdrawal ◽  
Withdrawal Symptoms ◽  
Smoking Abstinence ◽  
Socioeconomically Disadvantaged ◽  
Short Term ◽  
Quit Attempt ◽  
Insight Into

This study used data collected from a smoking cessation program ( N = 146) to evaluate whether subjective social status was indirectly associated with smoking cessation through nicotine withdrawal symptoms. Findings indicated that subjective social status was indirectly associated with smoking cessation through withdrawal symptoms, specifically through anger and anxiety symptoms. People with lower subjective social status reported more withdrawal symptoms, particularly symptoms related to anger and anxiety, shortly after a quit attempt, and as such, were less likely to achieve smoking abstinence. Findings from this study provide insight into why socioeconomically disadvantaged adults are less likely to remain abstinent after a quit attempt.

scholarly journals Activation of AMPK by metformin improves withdrawal signs precipitated by nicotine withdrawal

2018 ◽  
Vol 115 (16) ◽  
pp. 4282-4287 ◽  
Author(s):  
Julia K. Brynildsen ◽  
Bridgin G. Lee ◽  
Isaac J. Perron ◽  
Sunghee Jin ◽  
Sangwon F. Kim ◽  
...  
Keyword(s):  
United States ◽  
Smoking Cessation ◽  
The United States ◽  
Nicotine Withdrawal ◽  
Withdrawal Symptoms ◽  
Ampk Activation ◽  
Ampk Signaling ◽  
Amp Activated Protein Kinase ◽  
Multiple Health ◽  
Withdrawal Signs

Cigarette smoking is the leading cause of preventable disease and death in the United States, with more persons dying from nicotine addiction than any other preventable cause of death. Even though smoking cessation incurs multiple health benefits, the abstinence rate remains low with current medications. Here we show that the AMP-activated protein kinase (AMPK) pathway in the hippocampus is activated following chronic nicotine use, an effect that is rapidly reversed by nicotine withdrawal. Increasing pAMPK levels and, consequently, downstream AMPK signaling pharmacologically attenuate anxiety-like behavior following nicotine withdrawal. We show that metformin, a known AMPK activator in the periphery, reduces withdrawal symptoms through a mechanism dependent on the presence of the AMPKα subunits within the hippocampus. This study provides evidence of a direct effect of AMPK modulation on nicotine withdrawal symptoms and suggests central AMPK activation as a therapeutic target for smoking cessation.

Effectiveness of Nicotine Withdrawal Symptoms Management Program Using LINE Application to Increase Self-Efficacy for Industrial Workers

2021 ◽  
Vol 104 (12) ◽  
pp. 1920-1929
Keyword(s):  
Smoking Cessation ◽  
Self Efficacy ◽  
Nicotine Withdrawal ◽  
Management Program ◽  
Withdrawal Symptoms ◽  
Control Group ◽  
Industrial Workers ◽  
Exhaled Carbon Monoxide ◽  
Cigarette Craving ◽  
Withdrawal Management

Background: Smoking is a risk factor for chronic diseases. A combination of tobacco use with occupational hazards among industrial workers could increase the risk of occupational disease and injury. Nicotine is known to be highly addictive. It is difficult not only to maintain the decrease in smoking but also to continue quitting tobacco use. Moreover, nicotine withdrawal can be challenging and lead to failure in the smoking cessation process. Self-efficacy theory has been used recently for the development of effective smoking cessation programs. Objective: To develop an online nicotine withdrawal symptoms management program based on self-efficacy theory and examine its effectiveness. Materials and Methods: A quasi-experimental design with a control group pretest-posttest design was used. The sample consisted of male employees working in a consumer product manufacturing industry in Bangkok. An intervention group (n=28) received an online nicotine withdrawal symptoms management program via LINE application based on self-efficacy theory for one month. In comparison, participants in the control group (n=29) received a conventional smoking cessation program. The effectiveness of the intervention on nicotine withdrawal symptoms, cigarette craving, self-efficacy perception of nicotine withdrawal management, cigarette rolls per day, nicotine dependence level, exhaled carbon monoxide level, and smoking cessation behavior the first and fourth week were examined using a repeated-measures analysis of variance. Results: At one-month follow-up, there were significant differences between the two groups on nicotine withdrawal symptoms score, cigarette craving level, self-efficacy perception of nicotine withdrawal management, cigarette rolls per day, nicotine addiction level, exhaled carbon monoxide level, and smoking cessation behaviors (p<0.001). In addition, there was a significant difference in the self-reported nicotine withdrawal symptoms score in terms of irritability, anger, anxiety, concentration deficit, depression, and insomnia (p<0.001) between groups, between times, and between times and groups (p<0.001). Conclusion: Nicotine withdrawal symptoms management program using LINE application is effective in encouraging smoking cessation. Keywords: Smoking cessation; Nicotine withdrawal symptoms; LINE application; Industrial workers

Reduction of anxiety sensitivity in relation to nicotine withdrawal symptoms during smoking cessation: an examination among successful quitters

2017 ◽  
Vol 47 (4) ◽  
pp. 301-314 ◽  
Author(s):  
Jafar Bakhshaie ◽  
Michael J. Zvolensky ◽  
Kirsten J. Langdon ◽  
Adam M. Leventhal ◽  
Norman B. Schmidt
Keyword(s):  
Smoking Cessation ◽  
Anxiety Sensitivity ◽  
Nicotine Withdrawal ◽  
Withdrawal Symptoms

Effect of varenicline and bupropion SR on craving, nicotine withdrawal symptoms, and rewarding effects of smoking during a quit attempt

2007 ◽  
Vol 197 (3) ◽  
pp. 371-377 ◽  
Author(s):  
Robert West ◽  
Christine L. Baker ◽  
Joseph C. Cappelleri ◽  
Andrew G. Bushmakin
Keyword(s):  
Nicotine Withdrawal ◽  
Withdrawal Symptoms ◽  
Quit Attempt

scholarly journals Withdrawal Symptom, Treatment Mechanism, and/or Side Effect? Developing an Explicit Measurement Model for Smoking Cessation Research

2018 ◽  
Vol 22 (4) ◽  
pp. 482-491 ◽  
Author(s):  
Sarah S Tonkin ◽  
Trevor F Williams ◽  
Leonard J Simms ◽  
Stephen T Tiffany ◽  
Martin C Mahoney ◽  
...  
Keyword(s):  
Smoking Cessation ◽  
Side Effects ◽  
Negative Affect ◽  
Factor Model ◽  
Somatic Symptoms ◽  
Measurement Model ◽  
Nicotine Withdrawal ◽  
Data Driven ◽  
Withdrawal Symptoms ◽  
Treatment Mechanisms

Abstract Introduction Assessment of withdrawal symptoms, treatment mechanisms, and side effects is central to understanding and improving smoking cessation interventions. Though each domain is typically assessed separately with widely used questionnaires to separately assess each domain (eg, Minnesota Nicotine Withdrawal Scale = withdrawal; Questionnaire of Smoking Urges-Brief = craving; Positive and Negative Affect Schedule = affect; symptom checklist = side effects), there are substantial problems with this implicit “one questionnaire equals one construct” measurement model, including item overlap across questionnaires. This study sought to clarify the number and nature of constructs assessed during smoking cessation by developing an explicit measurement model. Methods Two subsamples were randomly created from 1246 smokers in a clinical trial. Exploratory and confirmatory factor analyses were conducted to identify and select a model that best represented the data. Measurement invariance was assessed to determine if the factors and their content were consistent prior to and during the quit. Improvement in construct overlap within this model was compared against the implicit measurement model using correlational analyses. Results A 5-factor measurement model composed of negative affect, somatic symptoms, sleep problems, positive affect, and craving fits the data well prior to and during quitting. All factor content except somatic symptoms was consistent over time. Correlational analyses indicated that the 5-factor model attenuated construct overlap compared to the implicit model. Conclusions The models generated from data-driven approaches (eg, the 5-factor model) reduced overlap and better represented the constructs underlying these measures. This approach created distinct, stable constructs that span over measures of side effects and potential treatment mechanisms. Implications This study demonstrated that measures assessing treatment mechanisms, withdrawal symptoms, and side effects contain problematic overlap that reduces the clarity of these key constructs. The use of data-driven approaches showed that these measures do not map on to their posited latent constructs (eg, the Minnesota Nicotine Withdrawal Scale does not yield a withdrawal factor). Rather, these measures form distinct, basic processes that may represent more meaningful constructs for future research on cessation and treatment. Assessments designed to individually examine these processes may improve the study of treatment mechanisms.

scholarly journals Anhedonia and Anxiety Sensitivity: Prospective Relationships to Nicotine Withdrawal Symptoms During Smoking Cessation

2013 ◽  
Vol 74 (3) ◽  
pp. 469-478 ◽  
Author(s):  
Kirsten J. Langdon ◽  
Adam M. Leventhal ◽  
Sherry Stewart ◽  
David Rosenfield ◽  
Dan Steeves ◽  
...  
Keyword(s):  
Smoking Cessation ◽  
Anxiety Sensitivity ◽  
Nicotine Withdrawal ◽  
Withdrawal Symptoms

Predictors of nicotine withdrawal symptoms: findings from the first randomized smoking cessation trial in a low-income country setting

2016 ◽  
Vol 61 (6) ◽  
pp. 701-708 ◽  
Author(s):  
Ziyad Ben Taleb ◽  
Kenneth D. Ward ◽  
Taghrid Asfar ◽  
Rana Jaber ◽  
Rehab Auf ◽  
...  
Keyword(s):  
Smoking Cessation ◽  
Low Income ◽  
Nicotine Withdrawal ◽  
Income Country ◽  
Withdrawal Symptoms ◽  
Low Income Country
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