scholarly journals Shared genetic contributions to early-onset drinking and drinking to cope motives

2012 ◽  
Vol 37 (10) ◽  
pp. 1176-1180 ◽  
Author(s):  
Kelly C. Young-Wolff ◽  
Kenneth S. Kendler ◽  
Carol A. Prescott
Keyword(s):  
Early Onset ◽  
Drinking To Cope ◽  
Early Onset Drinking ◽  
Genetic Contributions ◽  
Shared Genetic

scholarly journals Genetic-linked Inattentiveness Protects Individuals from Internet Overuse: A Genetic Study of Internet Overuse Evaluating Hypotheses Based on Addiction, Inattention, Novelty-seeking and Harm-avoidance

10.28945/3520 ◽  
2016 ◽  
Vol 19 ◽  
pp. 173-200
Author(s):  
Cheng Sun ◽  
Rita Spathis ◽  
Krithivasan Sankaranarayanan ◽  
Chim W. Chan ◽  
J. Koji Lum
Keyword(s):  
Internet Addiction ◽  
Genetic Study ◽  
Harm Avoidance ◽  
Novelty Seeking ◽  
Comt Val158met ◽  
Length Polymorphisms ◽  
Considerable Debate ◽  
Genetic Contributions ◽  
Genetic Results ◽  
Shared Genetic

The all-pervasive Internet has created serious problems, such as Internet overuse, which has triggered considerable debate over its relationship with addiction. To further explore its genetic susceptibilities and alternative explanations for Internet overuse, we proposed and evaluated four hypotheses, each based on existing knowledge of the biological bases of addiction, inattention, novelty-seeking, and harm-avoidance. Four genetic loci including DRD4 VNTR, DRD2 Taq1A, COMT Val158Met and 5-HTTLPR length polymorphisms were screened from seventy-three individuals. Our results showed that the DRD4 4R/4R individuals scored significantly higher than the 2R or 7R carriers in Internet Addiction Test (IAT). The 5-HTTLPR short/short males scored significantly higher in IAT than the long variant carriers. Bayesian analysis showed the most compatible hypothesis with the observed genetic results was based on attention (69.8%), whereas hypotheses based harm-avoidance (21.6%), novelty-seeking (7.8%) and addiction (0.9%) received little support. Our study suggests that carriers of alleles (DRD4 2R and 7R, 5-HTTLPR long) associated with inattentiveness are more likely to experience disrupted patterns and reduced durations of Internet use, protecting them from Internet overuse. Furthermore, our study suggests that Internet overuse should be categorized differently from addiction due to the lack of shared genetic contributions.

scholarly journals Shared genetic contributions to anxiety disorders and pathological gambling in a male population

2011 ◽  
Vol 132 (3) ◽  
pp. 406-412 ◽  
Author(s):  
Justine L. Giddens ◽  
Hong Xian ◽  
Jeffrey F. Scherrer ◽  
Seth A. Eisen ◽  
Marc N. Potenza
Keyword(s):  
Anxiety Disorders ◽  
Pathological Gambling ◽  
Male Population ◽  
Genetic Contributions ◽  
Shared Genetic

scholarly journals Childhood Risk Factors for Early-Onset Drinking*

2011 ◽  
Vol 72 (5) ◽  
pp. 741-751 ◽  
Author(s):  
John E. Donovan ◽  
Brooke S. G. Molina
Keyword(s):  
Risk Factors ◽  
Early Onset ◽  
Early Onset Drinking ◽  
Childhood Risk Factors

Early Onset Drinking

2014 ◽  
pp. 18-31
Author(s):  
Shauncie M. Skidmore ◽  
Rose A. Juhasz ◽  
Robert A. Zucker
Keyword(s):  
Early Onset ◽  
Early Onset Drinking

Shared Genetic Contributions to Cognition and Psychiatric Disorder Risk Based on Genome-Wide Data

2020 ◽  
Vol 87 (9) ◽  
pp. S338
Author(s):  
Laura Germine ◽  
Caitlin Carey ◽  
Yunru Huang ◽  
Stella Aslibekyan ◽  
Jordan Smoller ◽  
...  
Keyword(s):  
Psychiatric Disorder ◽  
Genome Wide ◽  
Genome Wide Data ◽  
Genetic Contributions ◽  
Shared Genetic ◽  
Disorder Risk

scholarly journals Early-onset drinking in Ireland: negative outcomes and behaviours

Public Health ◽  
2013 ◽  
Vol 127 (8) ◽  
pp. 788-790
Author(s):  
T.D. Cosco ◽  
K. Morgan ◽  
L. Currie ◽  
H. McGee
Keyword(s):  
Early Onset ◽  
Negative Outcomes ◽  
Early Onset Drinking

scholarly journals Shared Genetic Contributions to Pathological Gambling and Major Depression in Men

2005 ◽  
Vol 62 (9) ◽  
pp. 1015 ◽  
Author(s):  
Marc N. Potenza ◽  
Hong Xian ◽  
Kamini Shah ◽  
Jeffrey F. Scherrer ◽  
Seth A. Eisen
Keyword(s):  
Major Depression ◽  
Pathological Gambling ◽  
Genetic Contributions ◽  
Shared Genetic
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