Family based association analysis of statistically derived quantitative traits for drug use in ADHD and the dopamine transporter gene

2006 ◽  
Vol 31 (6) ◽  
pp. 1088-1099 ◽  
Author(s):  
Jessica Lasky-Su ◽  
Joseph Biederman ◽  
Alysa E. Doyle ◽  
Timothy Wilens ◽  
Michael Monuteaux ◽  
...  
Keyword(s):  
Drug Use ◽  
Dopamine Transporter ◽  
Association Analysis ◽  
Quantitative Traits ◽  
Transporter Gene ◽  
Dopamine Transporter Gene ◽  
Family Based

scholarly journals Lack of association between VNTR polymorphism of dopamine transporter gene (SLC6A3) and schizophrenia in a Brazilian sample

2004 ◽  
Vol 62 (4) ◽  
pp. 973-976 ◽  
Author(s):  
Quirino Cordeiro ◽  
Michael Talkowski ◽  
Joel Wood ◽  
Eliza Ikenaga ◽  
Homero Vallada
Keyword(s):  
Dopamine Transporter ◽  
Variable Number Tandem Repeat ◽  
Variable Number ◽  
Transporter Gene ◽  
Dopamine Transporter Gene ◽  
Brazilian Sample ◽  
Dopaminergic Dysfunction ◽  
Schizophrenic Patients ◽  
Family Based ◽  
Transmission Distortions

A role of dopaminergic dysfunction has been postulated in the aetiology of schizophrenia. We hypothesized that variations in the dopamine transporter gene (SLC6A3) may be associated with schizophrenia. We conducted case-control and family based analysis on the polymorphic SLC6A3 variable number tandem repeat (VNTR) in a sample of 220 schizophrenic patients, 226 gender and ethnic matched controls, and 49 additional case-parent trios. No differences were found in allelic or genotypic distributions between cases and controls and no significant transmission distortions from heterozygous parents to schizophrenic offspring were detected. Thus, our results do not support an association of the SLC6A3 VNTR with schizophrenia in our sample.

Association analysis of dopamine transporter gene ( SLC6A3 ) variants with risk for seizures and aggression in Border Collies

2021 ◽  
Author(s):  
Samantha L. Van Buren ◽  
Anita M. Oberbauer ◽  
Katie M. Minor ◽  
Janelle M. Belanger ◽  
Eva Furrow
Keyword(s):  
Dopamine Transporter ◽  
Association Analysis ◽  
Transporter Gene ◽  
Dopamine Transporter Gene
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