A light-controllable specific drug delivery nanoplatform for targeted bimodal imaging-guided photothermal/chemo synergistic cancer therapy

2018 ◽  
Vol 80 ◽  
pp. 308-326 ◽  
Author(s):  
Yuan Guo ◽  
Xing-Yue Wang ◽  
Yu-Li Chen ◽  
Feng-Qiu Liu ◽  
Mi-Xiao Tan ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Specific Drug ◽  
Bimodal Imaging

scholarly journals An iRGD peptide conjugated heparin nanocarrier for gastric cancer therapy

RSC Advances ◽  
2018 ◽  
Vol 8 (52) ◽  
pp. 30012-30020 ◽  
Author(s):  
Shichao Ai ◽  
Shuang Zhen ◽  
Zhijian Liu ◽  
Feng Sun ◽  
Xingchen He ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Delivery System ◽  
Delivery System ◽  
Specific Drug

A nontoxic, low immunogenic and high specific drug delivery system for gastric cancer.

Nanoparticle Targeting CD44-Positive Cancer Cells for Site-Specific Drug Delivery in Prostate Cancer Therapy

2016 ◽  
Vol 8 (45) ◽  
pp. 30722-30734 ◽  
Author(s):  
Wen-Ying Huang ◽  
Jia-Ni Lin ◽  
Jer-Tsong Hsieh ◽  
Shen-Chieh Chou ◽  
Chih-Ho Lai ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Drug Delivery ◽  
Cancer Therapy ◽  
Cancer Cells ◽  
Specific Drug ◽  
Site Specific ◽  
Prostate Cancer Therapy

Bioengineered Bacterial Outer Membrane Vesicles as Cell-Specific Drug-Delivery Vehicles for Cancer Therapy

ACS Nano ◽  
2014 ◽  
Vol 8 (2) ◽  
pp. 1525-1537 ◽  
Author(s):  
Vipul Gujrati ◽  
Sunghyun Kim ◽  
Sang-Hyun Kim ◽  
Jung Joon Min ◽  
Hyon E Choy ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Outer Membrane ◽  
Membrane Vesicles ◽  
Outer Membrane Vesicles ◽  
Specific Drug ◽  
Drug Delivery Vehicles ◽  
Delivery Vehicles ◽  
Bacterial Outer Membrane

Zinc-ion-mediated self-assembly of forky peptides for prostate cancer-specific drug delivery

2018 ◽  
Vol 54 (37) ◽  
pp. 4673-4676 ◽  
Author(s):  
Mingtao Tao ◽  
Keming Xu ◽  
Suyun He ◽  
Hongmei Li ◽  
Li Zhang ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Drug Delivery ◽  
Cancer Therapy ◽  
Self Assembly ◽  
Zinc Ion ◽  
Zinc Ions ◽  
Specific Drug ◽  
Prostate Cancer Therapy

A hexapeptide with a unique forky structure can form hydrogels triggered by zinc ions for prostate cancer therapy.

Design and development of 5-fluorouracil loaded biodegradable magnetic microspheres as site-specific drug delivery vehicle for cancer therapy

2021 ◽  
pp. 168853
Author(s):  
Srinivasan Ayyanaar ◽  
Rangaswamy Chinnabba Bhaskar ◽  
Selvaraj Esthar ◽  
Manokaran Vadivel ◽  
Jegathalaprathaban Rajesh ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Magnetic Microspheres ◽  
Specific Drug ◽  
Delivery Vehicle ◽  
Design And Development ◽  
Site Specific ◽  
Drug Delivery Vehicle

Modern Possibilities of Organ-Preserving Treatment in Children with Intraocular Retinoblastoma

2018 ◽  
Vol 5 (3) ◽  
pp. 175-187 ◽  
Author(s):  
O. V. Gorovtsova ◽  
T. L. Ushakova ◽  
V. G. Polyakov
Keyword(s):  
Drug Delivery ◽  
Survival Rate ◽  
Cancer Therapy ◽  
Neoadjuvant Chemotherapy ◽  
Patient Survival ◽  
Focal Therapy ◽  
Local Drug Delivery ◽  
Large Size ◽  
Intraocular Retinoblastoma

Retinoblastoma is one of highly curable diseases; today the total 5-year survival rate in patients with retinoblastoma exceeds 95%. The article summarizes the current world experience on treatment of patients with intraocular retinoblastoma. The treating skills of intraocular malignant tumor in children are a balance between the patient’s life and the preservation of an eye and its visual functions. The complex and challenging task is the treatment of common intraocular retinoblastoma groups «C», «D», «E» when the large size or localization of the tumor does not allow performing the local (focal) destruction of the tumor. As a rule, in such cases neoadjuvant chemotherapy (CT) is performed at the first stage in order to reduce the size of the tumor for further focal therapy. However, the analysed data on the effectiveness of neoadjuvant CT in combination with focal or radiotherapy demonstrated the limited possibilities of the proposed therapy. Local drug delivery in cancer therapy became a real breakthrough in the organ-preserving treatment of children with large intraocular retinoblastoma. The most widely used current methods of local drug delivery are intravitreal (IVitC) and selective intra-arterial chemotherapy (SIAC) as monotherapy or in combination with neoadjuvant CT and focal therapy which significantly increased the percentage of preserved eyes without radiotherapy administration or damage to the patient survival. The review discusses the different IVitC and SIAC techniques, chemotherapy schemes, dosages of chemotherapy, immediate and long-term complications of treatment.

Chitosan-Based Hydrogel Nanoparticles for Cancer Therapy

2017 ◽  
Vol 7 (04) ◽  
Author(s):  
Azadi A. ◽  
Khazaei M. ◽  
Ashrafi H.
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Recent Decade ◽  
Reticuloendothelial System ◽  
Malignant Neoplasms ◽  
Mortality And Morbidity ◽  
Hydrogel Nanoparticles ◽  
Tissue Invasion ◽  
Causes Of Mortality ◽  
Nanoparticulate Systems

Cancer, an uncontrollable growth of cells, is among the leading causes of mortality and morbidity throughout the world. Malignant neoplasms are difficult to treat diseases because of their single in kind characteristics such as tissue invasion, metastasis, evading reticuloendothelial system (RES) and so forth. In recent decade polymeric nanoparticulate systems has gained special attention in drug delivery and targeting among all biocompatible nanoforms. Among these systems, chitosan-based hydrogel nanoparticles have been wildly utilized for drug delivery purposes. The usage of chitosan nanogels in cancer therapy significantly improved in recent years. The various cancers were the target of chitosan nanogels. Also, modification of other delivery systems with chitosan were much reported. The aim of this study is the review and update of the recent studies on chitosan nanogels applications in cancer therapy by focus on cancer based classification.

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