Tumor-targeted and multi-stimuli responsive drug delivery system for near-infrared light induced chemo-phototherapy and photoacoustic tomography

2016 ◽  
Vol 38 ◽  
pp. 129-142 ◽  
Author(s):  
Qianhua Feng ◽  
Yuanyuan Zhang ◽  
Wanxia Zhang ◽  
Xiaoning Shan ◽  
Yujie Yuan ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Near Infrared ◽  
Infrared Light ◽  
Photoacoustic Tomography ◽  
Stimuli Responsive ◽  
Near Infrared Light

Gold Nanorods Coated with Mesoporous Silica Shell as Drug Delivery System for Remote Near Infrared Light-Activated Release and Potential Phototherapy

Small ◽  
2015 ◽  
Vol 11 (19) ◽  
pp. 2323-2332 ◽  
Author(s):  
Ji Liu ◽  
Christophe Detrembleur ◽  
Marie-Claire De Pauw-Gillet ◽  
Stéphane Mornet ◽  
Christine Jérôme ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Drug Delivery System ◽  
Delivery System ◽  
Gold Nanorods ◽  
Near Infrared ◽  
Silica Shell ◽  
Infrared Light ◽  
Near Infrared Light

Near-infrared light triggered drug delivery system for higher efficacy of combined chemo-photothermal treatment

2017 ◽  
Vol 51 ◽  
pp. 374-392 ◽  
Author(s):  
Yi Chen ◽  
Haohuan Li ◽  
Yueyang Deng ◽  
Haifeng Sun ◽  
Xue Ke ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Photothermal Treatment

Near-infrared light-triggered drug delivery system based on black phosphorus for in vivo bone regeneration

Biomaterials ◽  
2018 ◽  
Vol 179 ◽  
pp. 164-174 ◽  
Author(s):  
Xuzhu Wang ◽  
Jundong Shao ◽  
Mustafa Abd El Raouf ◽  
Hanhan Xie ◽  
Hao Huang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Bone Regeneration ◽  
Drug Delivery System ◽  
Delivery System ◽  
Near Infrared ◽  
Black Phosphorus ◽  
Infrared Light ◽  
Near Infrared Light

scholarly journals Improving Tumoral Acidic pH-Responsive Drug Efficiency Based on GO@Au Nanocomposite

2020 ◽  
Author(s):  
Mingqing Tang ◽  
Pengliang Xin ◽  
Hongjun Lin ◽  
Huangen Li
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Tumor Cells ◽  
Drug Delivery System ◽  
Delivery System ◽  
Near Infrared ◽  
Tumor Therapy ◽  
Infrared Light ◽  
Tumor Inhibition ◽  
Release Drug

Abstract Background: to accurately deliver drugs to the lesion site and realize its timed and quantitative release is the focus of tumor therapy. In this paper, a tumor targeted near-infrared light controlled release drug delivery system integrating hyperthermia and chemotherapy was successfully constructed by combining tumor hyperthermia and chemotherapy. Results: by hydrothermal method, Au nanoparticles were firstly loaded onto the GO surface to obtain GO@Au nanocomposites, then PEG was loaded onto the GO@Au by pH sensitive hydrazone bond to obtain GO@Au-PEG, and DOX is finally loaded onto the GO surface via π-π stacking. The target controlled release drug delivery system showed good tumor targeting property, can be the efficient transfer of drug to the tumor cells, and the tumor cells in near-infrared light control of DOX release. In vivo tumor inhibition experiments in mice, the targeted drug delivery system showed obvious tumor inhibition characteristics and had good effects of hyperthermia and chemotherapy. Conclusions: therefore, this tumor targeted near-infrared controlled release drug delivery system has great potential in tumor therapy.

Azo-functionalized Fe3O4 nanoparticles: a near-infrared light triggered drug delivery system for combined therapy of cancer with low toxicity

2016 ◽  
Vol 4 (21) ◽  
pp. 3660-3669 ◽  
Author(s):  
Ling Chen ◽  
Lin Wu ◽  
Fei Liu ◽  
Xueyong Qi ◽  
Yanru Ge ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Near Infrared ◽  
Combined Therapy ◽  
Infrared Light ◽  
Nir Light ◽  
Low Toxicity ◽  
Smart Drug ◽  
Smart Drug Delivery

A smart drug delivery system based on thermo-sensitive molecule was designed. When exposed to near infrared (NIR) light, Fe3O4 nanoparticles transfer the light to heat rapidly, leading to the cleavage of the Azo linker and the release of DOX.

A near infrared light-triggered human serum albumin drug delivery system with coordination bonding of indocyanine green and cisplatin for targeting photochemistry therapy against oral squamous cell cancer

2019 ◽  
Vol 7 (12) ◽  
pp. 5270-5282 ◽  
Author(s):  
Yuxin Wang ◽  
Diya Xie ◽  
Jiongru Pan ◽  
Chengwan Xia ◽  
Lei Fan ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Indocyanine Green ◽  
Human Serum ◽  
Drug Delivery System ◽  
Delivery System ◽  
Near Infrared ◽  
Cell Cancer ◽  
Infrared Light

To ensure site–specific drug release in tumor cells and cancer-associated fibroblasts and reduce the systemic toxicity of chemotherapy, a novel drug delivery system called human serum albumin-indocyanine green-cisplatin nanoparticles was developed.

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