scholarly journals Relevance of the setting reaction to the injectability of tricalcium phosphate pastes

2013 ◽  
Vol 9 (4) ◽  
pp. 6188-6198 ◽  
Author(s):  
E.B. Montufar ◽  
Y. Maazouz ◽  
M.P. Ginebra
Keyword(s):  
Tricalcium Phosphate ◽  
Setting Reaction

Fabrication of low‐crystallinity hydroxyapatite foam based on the setting reaction of α‐tricalcium phosphate foam

2008 ◽  
Vol 88A (3) ◽  
pp. 628-633 ◽  
Author(s):  
Satoshi Karashima ◽  
Akari Takeuchi ◽  
Shigeki Matsuya ◽  
Koh‐ichi Udoh ◽  
Kiyoshi Koyano ◽  
...  
Keyword(s):  
Tricalcium Phosphate ◽  
Setting Reaction ◽  
Low Crystallinity

Amorphous α-Tricalcium Phosphate: Preparation and Aqueous Setting Reaction

2004 ◽  
Vol 87 (6) ◽  
pp. 1126-1132 ◽  
Author(s):  
Uwe Gbureck ◽  
Jake E. Barralet ◽  
Lavinia Radu ◽  
Hans G. Klinger ◽  
Roger Thull
Keyword(s):  
Tricalcium Phosphate ◽  
Setting Reaction

In Situ X-Ray Diffraction Study of Phase Development during Hardening of β-Tricalcium Phosphate Bone Cements with Chitosan

2013 ◽  
Vol 587 ◽  
pp. 109-114 ◽  
Author(s):  
Marina Salvarani Tonoli ◽  
Marisa Masumi Beppu
Keyword(s):  
Phase Transformation ◽  
Tricalcium Phosphate ◽  
Chitosan Solution ◽  
Phase Evolution ◽  
Dicalcium Phosphate ◽  
X Ray Diffraction ◽  
X Ray ◽  
Setting Reaction ◽  
Phase Development ◽  
First Moment

The aim of this work was to study the phase transformation during the setting reaction of beta tricalcium phosphate (β-TCP) and phosphoric acid with chitosan solution added. To follow the kinetics of the phase transformation, two methods were used: x-ray diffraction (XRD) was used to study the phase evolution during the hardening process in real time, and was also used in samples where the reaction was supposedly stopped in different times using acetone, as indicated in literature. The setting reaction occurs so fast that the phase transformation could not be observed, but it was possible to invalidate the second mentioned method for this system, as it induces the final product dicalcium phosphate dihydrate DCPD (brushite) to be converted into his anhydrous form dicalcium phosphate DCP (monetite). The addition of chitosan in order to improve biocompatibility was successfully done, it could be observed that chitosan inhibitsbrushitecrystallization in the first moment of the reaction, but the final product was not affected by it.

Fabrication of interconnected porous calcium-deficient hydroxyapatite using the setting reaction of α tricalcium phosphate spherical granules

2017 ◽  
Vol 43 (14) ◽  
pp. 11149-11155 ◽  
Author(s):  
Tya Indah Arifta ◽  
Melvin L. Munar ◽  
Kanji Tsuru ◽  
Kunio Ishikawa
Keyword(s):  
Tricalcium Phosphate ◽  
Setting Reaction

Preparation of Brushite Bone Cement with a Drug Containing β-Tricalcium Phosphate Granules

2016 ◽  
Vol 720 ◽  
pp. 143-146 ◽  
Author(s):  
In Cheol Lee ◽  
Tai Joo Chung ◽  
Kyung Sik Oh
Keyword(s):  
Heat Treatment ◽  
Elevated Temperature ◽  
Thermogravimetric Analysis ◽  
Bone Cement ◽  
Tricalcium Phosphate ◽  
Temperature Increase ◽  
Drug Loading ◽  
Starting Material ◽  
Setting Reaction ◽  
Gentamicin Sulfate

Brushite bone cement containing a drug was prepared using the dense granular β-tricalciump phospahte (β-TCP) as a starting material. The setting reaction was not significantly affected by loading antibiotics within the granules. Heat treatment of the granule at elevated temperature resulted in the suppression of temperature increase during setting, which provided benefits in drug loading. The amount of gentamicin sulfate infiltrated in the β-TCP granules was determined by thermogravimetric analysis and was found to be meaningful considering the MIC of microorganisms.

The Influence of Three Additives on the Setting Reaction Kinetics and Mechanical Strength Evolution of [Alpha]-Tricalcium Phosphate Cements

2011 ◽  
Vol 493-494 ◽  
pp. 397-402
Author(s):  
H.A.I. Cardoso ◽  
M. Motisuke ◽  
Cecília A.C. Zavaglia
Keyword(s):  
Calcium Phosphate ◽  
Mechanical Strength ◽  
Reaction Kinetics ◽  
Tricalcium Phosphate ◽  
Hydrogen Phosphate ◽  
Disodium Hydrogen Phosphate ◽  
Setting Reaction ◽  
Calcium Phosphate Cements ◽  
Strength Evolution ◽  
Low Load

Among the calcium phosphate cements, the system based on alpha-tricalcium phosphate (α-TCP) combines several interesting properties. However, these cements have their use limited to low load applications. The main objective of this study is to evaluate the influence of three different additives on the setting reaction kinetics and mechanical strength evolution of calcium phosphate cements as a function of time. The cement was obtained by mixing α-TCP powder with four different aqueous solutions containing or not containing disodium hydrogen phosphate (Na2HPO4), citric acid (C6H8O7) and/or tannic acid (C76H52O46). It was observed that two cement samples, one of them containing Na2HPO4 and C6H8O7 and another containingNa2HPO4 and C76H52O46 in the liquid phase, presented faster setting reaction and higher mechanical properties. These cements are more suitable for application as bone cement.

Fast Setting Pre-Mixed Calcium Phosphate Bone Cements Based on α-Tricalcium Phosphate

2014 ◽  
Vol 604 ◽  
pp. 204-207 ◽  
Author(s):  
Zilgma Irbe ◽  
Guna Krieke ◽  
Kristine Salma-Ancane ◽  
Liga Berzina-Cimdina
Keyword(s):  
Compressive Strength ◽  
Liquid Phase ◽  
Calcium Phosphate ◽  
Tricalcium Phosphate ◽  
Aqueous Fluid ◽  
Dihydrogen Phosphate ◽  
Bone Cements ◽  
Polypropylene Glycol ◽  
Setting Reaction ◽  
Calcium Phosphate Cements

Conventional calcium phosphate bone cements are self setting water based pastes. Recently pre-mixed calcium phosphate bone cements have been proposed that have non-aqueous fluid as liquid phase of the paste. Such cements thus only start setting reaction in contact with body fluids. In this work the properties (cohesion, compressive strength, phase composition) of pre-mixed calcium phosphate cements based on α-tricalcium phosphate and calcium dihydrogen phosphate monohydrate are described. Properties of several cement compositions are examined and compared to properties of β-tricalcium phosphate and calcium dihydrogen phosphate monohydrate based cements. It was found that α-tricalcium phosphate and calcium dihydrogen phosphate monohydrate based cements have higher compressive strength (10 - 15 MPa) than corresponding β-tricalcium phosphate and calcium dihydrogen phosphate monohydrate based cements (10 - 6 MPa). Out of examined cement paste liquids (glycerol, polyethylene glycol and polypropylene glycol) cements using glycerol as the liquid phase had higher compressive strength and are more cohesive.

Effect of Added Tricalcium Phosphate on Basic Properties of Apatite Cement

2007 ◽  
Vol 361-363 ◽  
pp. 339-342
Author(s):  
Akari Takeuchi ◽  
Akinari Nakagawa ◽  
Shigeki Matsuya ◽  
Ishikawa Kunio
Keyword(s):  
Crystal Growth ◽  
Mechanical Strength ◽  
Tricalcium Phosphate ◽  
Setting Time ◽  
Tetracalcium Phosphate ◽  
Initial Setting Time ◽  
Setting Reaction ◽  
Phosphate Ions ◽  
Initial Setting ◽  
Apatite Cement

Effect of added α-tricalcium phosphate (α-TCP) and β-TCP was investigated to understand the setting reaction of apatite cement consisting of tetracalcium phosphate (TTCP) and dicalcium phosphate anhydrous (DCPA). Addition of TCP delayed the initial setting time because TCP was not involved in the initial setting reaction and resulted in the decreased initial mechanical strength. After the initial setting of the cement due to the conversion of TTCP and DCPA into apatite, α-TCP dissolved to supply calcium and phosphate ions and they were consumed for crystal growth of apatite. Therefore, mechanical strength of the apatite cement containing α-TCP was increased. In contrast, added β-TCP showed no reactivity in the cement and thus result in the decreased mechanical strength.

scholarly journals Robocasting of biomimetic hydroxyapatite scaffolds using self-setting inks

2014 ◽  
Vol 2 (33) ◽  
pp. 5378-5386 ◽  
Author(s):  
Y. Maazouz ◽  
E. B. Montufar ◽  
J. Guillem-Marti ◽  
I. Fleps ◽  
C. Öhman ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
High Temperature ◽  
Tricalcium Phosphate ◽  
Setting Reaction ◽  
Biomimetic Hydroxyapatite

A new self-setting ceramic ink was developed for robocasting of biomimetic hydroxyapatite scaffolds, based on alpha-tricalcium phosphate and gelatine. After setting a biomimetic hydroxyapatite is obtained, with higher reactivity and resorbability than high-temperature sintered hydroxyapatite. The setting reaction of the ink results in a significant increase of the mechanical properties of the scaffolds.

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