Cardiac MRI in Ischemic Heart Disease with Severe Coronary Artery Stenosis

2006 ◽  
Vol 13 (11) ◽  
pp. 1387-1393 ◽  
Author(s):  
Muharrem Unlu ◽  
Yonca Anik ◽  
Ali Demirci ◽  
Dilek Ural ◽  
Goksel Kahraman ◽  
...  
Keyword(s):  
Heart Disease ◽  
Coronary Artery ◽  
Ischemic Heart Disease ◽  
Cardiac Mri ◽  
Coronary Artery Stenosis ◽  
Artery Stenosis ◽  
Ischemic Heart ◽  
Severe Coronary Artery

scholarly journals The structure of myocardial nerve plexus of human auricle of the right atrium and its relation to myocardial ischemia, functional status of the heart, and age

Medicina ◽  
2008 ◽  
Vol 44 (1) ◽  
pp. 40
Author(s):  
Aušra Burkauskienė ◽  
Vidmantas Aželis ◽  
Žibuoklė Senikienė ◽  
Vitas Linonis ◽  
Irina Ramanauskienė
Keyword(s):  
Heart Disease ◽  
Coronary Artery ◽  
Myocardial Ischemia ◽  
Ischemic Heart Disease ◽  
Coronary Artery Stenosis ◽  
Ischemic Heart ◽  
Nerve Plexus ◽  
Control Group ◽  
Disease Group ◽  
The Right

The aim of this study was to investigate and evaluate morphometrically the relationship between changes in the structure of myocardial nerve plexus of the right atrium auricle and myocardial ischemia, parameters reflecting functional status of the heart, and age. A total of 56 females and males aged 20–94 years were investigated. Ischemic heart disease group consisted of 39 persons (their mean age was 63.83±15.67 years). The control group comprised 17 persons (the mean age was 60.53±9.89 years). Control group consisted of deceased persons who according to the pathologic and anatomic examination were not diagnosed with cardiac pathology leading to heart lesions or overload. Ischemic heart disease group consisted of patients who underwent aorta-coronary artery bypass grafting surgery. In ischemic heart disease group, degree of coronary artery stenosis was evaluated as well as the major indicators reflecting the size of atria and formation of postinfarction scar. After examination, postinfarction scars were found in 18 (46.2%) persons; no scars were found in 21 (53.8%) persons. Neurohistochemical method and video microscopy were employed for the evaluation of quantitative changes in the structure of the myocardial nerve plexus. In ischemic heart disease group, the structures of nerve plexus occupied 5.0±1.0% of the area, perimeter was 10 488±2134 mm, and number of the structures was 2698±981; the same parameters in the control group were 6.0±1.4%, 13 008±443 mm, and 3469±1511, respectively. In persons with postinfarction scar, the number of nerve plexus structures was lower by 9.3%, area by 8.9%, perimeter by 9.7% on average as compared to ischemic heart disease group without a scar. Regression analysis did not reveal any statistically significant correlation between the degree of coronary artery stenosis and quantitive parameters of nerve plexus (P>0.05). Changes in quantitative parameters of nerve plexus were not related to compensatory dilation of the atria – echoscopy parameters of long and short axes. The results showed that the number, area, and perimeter of nerve plexus structures decreases at the same rate both in healthy subjects and patients with ischemic heart disease starting the fifth decade of life.

P251 Fragmented QRS in prediction of ischemic heart disease diagnosed by stress cardiovascular magnetic resonance imaging

2020 ◽  
Vol 41 (Supplement_1) ◽  
Author(s):  
P Yooprasert ◽  
P Vathesatogkit ◽  
V Thirawuth ◽  
W Prasertkulchai ◽  
T Tangcharoen
Keyword(s):  
Diabetes Mellitus ◽  
Coronary Artery Disease ◽  
Heart Disease ◽  
Coronary Artery ◽  
Ischemic Heart Disease ◽  
Cardiac Mri ◽  
Ischemic Heart ◽  
Fragmented Qrs ◽  
History Of ◽  
Artery Disease

Abstract Funding Acknowledgements None Background Fragmented QRS complex (fQRS) on 12-lead EKG is not uncommon in general population. Previous studies found an association between fQRS and myocardial scar, heart failure, and increased cardiac mortality. However, data in adults without history of coronary artery disease is limited. We aimed to evaluate whether there is an association between fQRS and ischemic heart disease (IHD) diagnosed by stress cardiac MRI. Method We retrospectively reviewed data from 604 patients who underwent stress cardiac MRI, in which 50 patients were excluded due to known history of coronary artery disease or incomplete stress test. A positive result was defined as stress-induced perfusion defect in at least 2 contiguous myocardial segments corresponding to epicardial coronary territory, or a presence of ischemic scar. The 12-lead EKG done on the same day with MRI, prior to stress testing, were analyzed. Fragmented QRS was defined as the presence of additional R wave (R’), notching in the nadir of R or S wave, or the presence of more than one R’ in any EKG leads. Both cardiac MRI and EKG were analyzed by two independent observers. Result   Final analysis included 554 patients, 39% were male, with a mean age of 67.8 ± 11.1 years. There was positive stress cardiac MRI in 219 patients (39.5%). Older age, diabetes mellitus, and hypertension were more frequent in the positive group (p <0.05). fQRS was identified in 300 patients (54.2%). Baseline characteristic did not differ significantly between patients with and without fQRS. There is an association between fQRS and IHD, OR 1.605 (95% CI 1.136-2.269), p = 0.007. Using linear regression, the number of leads with presence of fQRS showed an association with IHD (OR 1.204, p = 0.005). After adjustment for age, diabetes, hypertension, renal function, and left ventricular ejection fraction, the strong association between fQRS and IHD persisted, OR 1.709 (95% CI 1.182-2.470), p = 0.004. Conclusion In patients without known history of coronary artery disease, fragmented QRS is independently associated with ischemic heart disease diagnosed by stress cardiac MRI. Multiple regression analysis OR 95% CI p-value Age (years) 1.013 0.992 - 1.035 0.234 Diabetes mellitus 1.532 1.032 - 2.274 0.034 Hypertension 1.194 0.737 - 1.935 0.471 GFR (ml/min/1.73m²) 0.999 0.987 - 1.011 0.904 LV ejection fraction (%) 0.972 0.950 - 0.994 0.014 fragmented QRS 1.709 1.182 - 2.470 0.004

Abstract 268: The Increased Visceral Fat Thickness In Nafld Patients Enhances The Risk Of Coronary Artery Stenosis

Hypertension ◽  
2014 ◽  
Vol 64 (suppl_1) ◽  
Author(s):  
PENG Y CAO ◽  
HE CAI ◽  
MIN LIU ◽  
XIN Y ZHANG ◽  
SHUI YU ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Coronary Artery ◽  
Visceral Fat ◽  
Coronary Artery Stenosis ◽  
Artery Stenosis ◽  
Severe Stenosis ◽  
Severe Coronary Artery ◽  
Fat Thickness ◽  
The Relationship

Background: Non alcoholic fatty liver disease (NAFLD) is an independent risk factor of cardiovascular disease (CVD). In this research, we want exploring the relationship between NAFLD, visceral fat thickness and the severity of coronary artery disease. Methods: 1, The relationship between NAFLD, visceral fat thickness and severity of coronary heart disease(323 people). 2, The correlation between severe NAFLD and visceral fat thickness in the severe stenosis of coronary heart disease(197 people). Results: 1, the proportion of NAFLD was significantly increased by 16% and 19% in different coronary artery stenosis than in the normal group. Along with the increasing degree of coronary artery stenosis, the total visceral fat thickness increase, especially the epicardial layer (the moderate stenosis increased by 23% and the severe stenosis increased by 54% than without stenosis). 2, In the severe coronary artery stenosis group, the patients were divided into NAFLD group and non NAFLD group. compared to non NAFLD group, the epicardial, liver, renal, before the perirenal fat and the coronary score significantly increased in the NAFLD group (10%, 22%, 32%, 36% and 27%, respectively) .Along with the increase of coronary score , the epicardial fat thickness was increased significantly (16% and 34%, respectively) in the non NAFLD group; but the epicardial thickness of the NAFLD group was slightly increased (8% and 8%, respectively), there was no significant difference among the subgroups. Furthermore,not only in NAFLD group but also in non NAFLD group, the visceral fat thickness of the other three sections have no significant change among the three subgroups. Conclusion: Both the NAFLD and the epicardial adipose layer thickening can increase the risk of coronary artery stenosis. In the patients with the severe coronary artery stenosis, the NAFLD patients are more likely to increase the accumulation of the visceral fat thickness than the non NAFLD patients. Under the same thickness of the epicardium, the degree of coronary artery lesions is lighter in the NAFLD patients; it may be related to AMPK wich may have the myocardial protective effects.

Gender Differences in Non-Obstructive Coronary Artery Disease

2020 ◽  
Vol 26 ◽  
Author(s):  
Maria Bergami ◽  
Marialuisa Scarpone ◽  
Edina Cenko ◽  
Elisa Varotti ◽  
Peter Louis Amaduzzi ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Gender Differences ◽  
Heart Disease ◽  
Coronary Artery ◽  
Ischemic Heart Disease ◽  
Coronary Arteries ◽  
Obstructive Coronary Artery Disease ◽  
Ischemic Heart ◽  
Current Evidence ◽  
Artery Disease

: Subjects affected by ischemic heart disease with non-obstructive coronary arteries constitute a population that has received increasing attention over the past two decades. Since the first studies with coronary angiography, female patients have been reported to have non-obstructive coronary artery disease more frequently than their male counterparts, both in stable and acute clinical settings. Although traditionally considered a relatively infrequent and low-risk form of myocardial ischemia, its impact on clinical practice is undeniable, especially when it comes to infarction, where the prognosis is not as benign as previously assumed. Unfortunately, despite increasing awareness, there are still several questions left unanswered regarding diagnosis, risk stratification and treatment. The purpose of this review is to provide a state of the art and an update on current evidence available on gender differences in clinical characteristics, management and prognosis of ischemic heart disease with non-obstructive coronary arteries, both in the acute and stable clinical setting.

Evaluation of reconstructive coronary artery surgery in the treatment of ischemic heart disease

1969 ◽  
Vol 23 (1) ◽  
pp. 127-128
Author(s):  
J.A. McEachen ◽  
R.T. Smith ◽  
J.A. Cannon ◽  
P.G. Gaal ◽  
J.H. Davis ◽  
...  
Keyword(s):  
Heart Disease ◽  
Coronary Artery ◽  
Ischemic Heart Disease ◽  
Ischemic Heart ◽  
Coronary Artery Surgery

scholarly journals Shear-induced platelet aggregation increases in patients with proximal and severe coronary artery stenosis

2002 ◽  
Vol 25 (4) ◽  
pp. 154-160 ◽  
Author(s):  
Koichi Kawano ◽  
Hideaki Yoshino ◽  
Nobuo Aoki ◽  
Hiroshi Udagawa ◽  
Atsushi Watanuki ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Platelet Aggregation ◽  
Coronary Artery Stenosis ◽  
Artery Stenosis ◽  
Severe Coronary Artery

Cardiac MRI of ischemic heart disease at 3T: Potential and challenges

2008 ◽  
Vol 65 (1) ◽  
pp. 15-28 ◽  
Author(s):  
Oliver Wieben ◽  
Christopher Francois ◽  
Scott B. Reeder
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Cardiac Mri ◽  
Ischemic Heart
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