Chinese Herbal Medicine in the Treatment of Chronic Kidney Disease

2005 ◽  
Vol 12 (3) ◽  
pp. 276-281 ◽  
Author(s):  
Xiaomei Li ◽  
Haiyan Wang
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Herbal Medicine ◽  
Chinese Herbal Medicine ◽  
Chinese Herbal

scholarly journals Association Between Chinese Herbal Medicine Therapy and the Risk of Chronic Kidney Disease in Gout Patients

2021 ◽  
Vol 12 ◽  
Author(s):  
Yan-Zhuan Xiao ◽  
Zhi-Zhong Ye ◽  
Yuan-Tong Liang ◽  
Xin-Peng Chen ◽  
Yu-Hsun Wang ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Herbal Medicine ◽  
Chinese Herbal Medicine ◽  
Conditional Logistic Regression ◽  
International Classification Of Diseases ◽  
Population Based ◽  
Research Database ◽  
Chinese Herbal ◽  
Incidence Of Ckd

Background: Chinese herbal medicine (CHM) has been nationally and globally used in treating gout for over a millennium. The potential relationship between the incidence of chronic kidney disease (CKD) in gout patients and CHM therapy is unclear. Thus, this study aimed to provide some evidence regarding the relationship between CHM therapy and the occurrence of CKD in gout patients.Methods: We used data from the National Health Insurance Research database (NHIRD) in Taiwan. In this population-based nested case-control study, all participants were identified by International Classification of Diseases, Ninth Revision (ICD-9). Conditional logistic regression was used to calculate the odds ratio (OR) of the risk of CKD in gout patients treated with CHM therapy.Results: Data on 1718 gout patients with CKD and 1:1 matched 1718 gout patients without CKD were collected for analysis. The results showed that CHM therapy in gout patients did not increase the risk of developing CKD (adjusted OR = 1.01; 95% confidence interval [CI]: 0.86–1.18; p > 0.05). Moreover, CHM therapy in gout patients for >365 days did not increase the incidence of CKD (adjusted OR = 1.30; 95% CI: 0.90–1.88; p = 0.162).Conclusion: Traditional CHM therapy does not increase the incidence of CKD in gout patients.

scholarly journals Association of prescribed Chinese herbal medicine use with risk of end-stage renal disease in patients with chronic kidney disease

2015 ◽  
Vol 88 (6) ◽  
pp. 1365-1373 ◽  
Author(s):  
Ming-Yen Lin ◽  
Yi-Wen Chiu ◽  
Jung-San Chang ◽  
Hung-Lung Lin ◽  
Charles Tzu-Chi Lee ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Herbal Medicine ◽  
Renal Disease ◽  
Chinese Herbal Medicine ◽  
End Stage Renal Disease ◽  
Medicine Use ◽  
Chinese Herbal ◽  
Stage Renal Disease ◽  
End Stage

Increased risk of chronic kidney disease among users of non-prescribed Chinese herbal medicine in Taiwan

2012 ◽  
Vol 55 (2) ◽  
pp. 155-159 ◽  
Author(s):  
Chuan-Fa Hsieh ◽  
Song-Lih Huang ◽  
Chien-Lung Chen ◽  
Wei-Ta Chen ◽  
Huan-Cheng Chang ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Herbal Medicine ◽  
Chinese Herbal Medicine ◽  
Chinese Herbal ◽  
Increased Risk

scholarly journals The Efficacy and Mechanism of Chinese Herbal Medicine on Diabetic Kidney Disease

2019 ◽  
Vol 2019 ◽  
pp. 1-14
Author(s):  
Zhenzhen Lu ◽  
Yifei Zhong ◽  
Wangyi Liu ◽  
Ling Xiang ◽  
Yueyi Deng
Keyword(s):  
Kidney Disease ◽  
Herbal Medicine ◽  
Chinese Herbal Medicine ◽  
Diabetic Kidney Disease ◽  
Mesangial Cells ◽  
Symptom Relief ◽  
Glomerular Sclerosis ◽  
Diabetic Kidney ◽  
Chinese Herbal ◽  
Stage Renal Disease

Diabetic kidney disease (DKD) is the most common microvascular complication of diabetes and is one of the main causes of end-stage renal disease (ESRD) in many countries. The pathological features of DKD are the hypertrophy of mesangial cells, apoptosis of podocytes, glomerular basement membrane (GBM) thickening, accumulation of extracellular matrix (ECM), glomerular sclerosis, and tubulointerstitial fibrosis. The etiology of DKD is very complicated and many factors are involved, such as genetic factors, hyperglycemia, hypertension, hyperlipidemia, abnormalities of renal hemodynamics, and metabolism of vasoactive substances. Although some achievements have been made in the exploration of the pathogenesis of DKD, the currently available clinical treatment methods are still not completely effective in preventing the progress of DKD to ESRD. CHM composed of natural products has traditionally been used for symptom relief, which may offer new insights into therapeutic development of DKD. We will summarize the progress of Chinese herbal medicine (CHM) in the treatment of DKD from two aspects. In clinical trials, the Chinese herbal formulas were efficacy and safety confirmed by the randomized controlled trials. In terms of experimental research, studies provided evidence for the efficacy of CHM from the perspectives of balancing metabolic disorders, reducing inflammatory response and oxidative stress, antifibrosis, protecting renal innate cells, and regulating microRNA and metabolism. CHM consisting of different ingredients may play a role in synergistic interactions and multiple target points in the treatment of DKD.

scholarly journals Chinese Herbal Medicine in Ameliorating Diabetic Kidney Disease via Activating Autophagy

2019 ◽  
Vol 2019 ◽  
pp. 1-10
Author(s):  
Yuyang Wang ◽  
Hailing Zhao ◽  
Qian Wang ◽  
Xuefeng Zhou ◽  
Xiaoguang Lu ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Herbal Medicine ◽  
Chinese Herbal Medicine ◽  
Diabetic Kidney Disease ◽  
Kidney Injury ◽  
Public Health Problem ◽  
Current Status ◽  
Diabetic Patients ◽  
Diabetic Kidney ◽  
Chinese Herbal

Diabetic kidney disease (DKD), a leading cause of end-stage renal disease (ESRD), has become a serious public health problem worldwide and lacks effective therapies due to its complex pathogenesis. Recent studies suggested defective autophagy involved in the pathogenesis and progression of DKD. Chinese herbal medicine, as an emerging option for the treatment of DKD, could improve diabetic kidney injury by activating autophagy. In this review, we briefly summarize underlying mechanisms of autophagy dysregulation in DKD, including AMP-activated protein kinase (AMPK), the mechanistic target of rapamycin (mTOR), and the sirtuin (Sirt) pathways, and we particularly concentrate on the current status of Chinese herbal medicine treating DKD by regulating autophagy. The advances in our understanding regarding the treatment of DKD via regulating autophagy with Chinese herbal medicine will enhance the clinical application of Chinese medicine as well as discovery of novel therapeutic agents for diabetic patients.

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