An immuno-MALDI mass spectrometry assay for the oral cancer biomarker, matrix metalloproteinase-1, in dried saliva spot samples

2020 ◽  
Vol 1100 ◽  
pp. 118-130 ◽  
Author(s):  
Yung-Chin Hsiao ◽  
Shih-Yu Lin ◽  
Kun-Yi Chien ◽  
Szu-Fan Chen ◽  
Chia-Chun Wu ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Oral Cancer ◽  
Matrix Metalloproteinase ◽  
Maldi Mass Spectrometry ◽  
Cancer Biomarker ◽  
Matrix Metalloproteinase 1 ◽  
Mass Spectrometry Assay

scholarly journals Soluble Expression of Bladder Cancer Biomarker Matrix Metalloproteinase 1

2014 ◽  
Vol 29 (4) ◽  
pp. 275-280
Author(s):  
Xuefei Jin ◽  
Dan Zhang ◽  
Hongyan Li ◽  
Ning Jin ◽  
Tingting Liu ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Matrix Metalloproteinase ◽  
Cancer Biomarker ◽  
Soluble Expression ◽  
Matrix Metalloproteinase 1

Matrix metalloproteinase and tissue inhibitor of metalloproteinase in serum and synovial fluid of osteoarthritic dogs

2006 ◽  
Vol 19 (01) ◽  
pp. 49-55 ◽  
Author(s):  
J. K. Roush ◽  
T. Schermerhorn ◽  
K. E. Mitchell ◽  
B. J. Salinardi
Keyword(s):  
Mass Spectrometry ◽  
Synovial Fluid ◽  
Matrix Metalloproteinase ◽  
Tissue Inhibitor Of Metalloproteinase ◽  
Matrix Metalloproteinase 2 ◽  
Tissue Inhibitor ◽  
Matrix Metalloproteinase 1 ◽  
Early Oa

SummaryTo better understand the mechanisms responsible for the pathological processes of osteoarthritis (OA) and to potentially identify a profile of changes that could be predictive of early OA, matrix metalloproteinase-1 (MMP-1) and tissue inhibitor of matrix metalloproteinase-2 (TIMP-2) in the synovial fluid and serum of normal and osteoarthritic dogs were examined. The concentration of MMP-1 in the synovial fluid of osteoarthritic dogs (0.62 ± 0.16), as measured by densitometry, was significantly higher than that found in control dogs (0.42 ± 0.19) (P = 0.03). The concentration of MMP-1 in the serum of osteoarthritic dogs (0.74 ± 0.16) was significantly less than that found in control dogs (0.87 ± 0.08) (P = 0.05). The concentration of TIMP-2 in the synovial fluid of osteoarthritic dogs (46.2 ± 21.9 ng/ml) was significantly less than that of control dogs (122.0 ± 66.5 ng/ml) (P = 0.009). The concentration of TIMP-2 in the serum of osteoarthritic dogs (116.2 ± 43.1 ng/ml) was not significantly different than that of control dogs (95.1 ± 94.4 ng/ml) (P = 0.554). In addition, a phospho-tyrosine immunoprecipitation and mass spectrometry were used to isolate and identify interferonalpha in canine synovial fluid.

Rapid label-free profiling of oral cancer biomarker proteins using nano-UPLC-Q-TOF ion mobility mass spectrometry

2016 ◽  
Vol 10 (3) ◽  
pp. 280-289 ◽  
Author(s):  
Ala. F. Nassar ◽  
Brad J. Williams ◽  
Dustin C. Yaworksy ◽  
Vyomesh Patel ◽  
James F. Rusling
Keyword(s):  
Mass Spectrometry ◽  
Oral Cancer ◽  
Ion Mobility ◽  
Cancer Biomarker ◽  
Ion Mobility Mass Spectrometry ◽  
Label Free

scholarly journals Evaluating the potential of a novel oral lesion exudate collection method coupled with mass spectrometry-based proteomics for oral cancer biomarker discovery

2011 ◽  
Vol 8 (1) ◽  
pp. 13 ◽  
Author(s):  
Joel A Kooren ◽  
Nelson L Rhodus ◽  
Chuanning Tang ◽  
Pratik D Jagtap ◽  
Bryan J Horrigan ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Oral Cancer ◽  
Biomarker Discovery ◽  
Oral Lesion ◽  
Cancer Biomarker ◽  
Collection Method
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