A label-free colorimetric isothermal cascade amplification for the detection of disease-related nucleic acids based on double-hairpin molecular beacon

2017 ◽  
Vol 957 ◽  
pp. 55-62 ◽  
Author(s):  
Dong Wu ◽  
Huo Xu ◽  
Haimei Shi ◽  
Weihong Li ◽  
Mengze Sun ◽  
...  
Keyword(s):  
Nucleic Acids ◽  
Molecular Beacon ◽  
Label Free ◽  
Cascade Amplification

A facile deoxyuridine/biotin-modified molecular beacon for simultaneous detection of proteins and nucleic acids via a label-free and background-eliminated fluorescence assay

The Analyst ◽  
2019 ◽  
Vol 144 (18) ◽  
pp. 5504-5510 ◽  
Author(s):  
Fei Yin ◽  
Liqi Liu ◽  
Xia Sun ◽  
Laiyong Hou ◽  
Yu Lu ◽  
...  
Keyword(s):  
Early Diagnosis ◽  
Nucleic Acids ◽  
Molecular Beacon ◽  
Simultaneous Detection ◽  
Cancer Biomarkers ◽  
Label Free ◽  
Early Diagnosis Of Cancer ◽  
Different Types ◽  
Diagnosis Of Cancer ◽  
Modified Molecular Beacon

Simultaneous detection of different types of cancer biomarkers (nucleic acids and proteins) could facilitate early diagnosis of cancer and clinical treatment.

scholarly journals Correction: A facile deoxyuridine/biotin-modified molecular beacon for simultaneous detection of proteins and nucleic acids via a label-free and background-eliminated fluorescence assay

The Analyst ◽  
2020 ◽  
Vol 145 (22) ◽  
pp. 7448-7448
Author(s):  
Fei Yin ◽  
Liqi Liu ◽  
Xia Sun ◽  
Laiyong Hou ◽  
Yu Lu ◽  
...  
Keyword(s):  
Nucleic Acids ◽  
Molecular Beacon ◽  
Simultaneous Detection ◽  
Fluorescence Assay ◽  
Label Free ◽  
Modified Molecular Beacon

Correction for ‘A facile deoxyuridine/biotin-modified molecular beacon for simultaneous detection of proteins and nucleic acids via a label-free and background-eliminated fluorescence assay’ by Fei Yin, et al., Analyst, 2019, 144, 5504–5510, DOI: 10.1039/C9AN01016E.

Mercury Electrodes in Nucleic Acid Electrochemistry: Sensitive Analytical Tools and Probes of DNA Structure. A Review

2004 ◽  
Vol 69 (4) ◽  
pp. 715-747 ◽  
Author(s):  
Miroslav Fojta
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acids ◽  
Double Helix ◽  
Dna Structure ◽  
Electrochemical Analysis ◽  
Label Free ◽  
Helix Formation ◽  
Mercury Electrodes ◽  
Dna Strand ◽  
Dna Double Helix

This review is devoted to applications of mercury electrodes in the electrochemical analysis of nucleic acids and in studies of DNA structure and interactions. At the mercury electrodes, nucleic acids yield faradaic signals due to redox processes involving adenine, cytosine and guanine residues, and tensammetric signals due to adsorption/desorption of polynucleotide chains at the electrode surface. Some of these signals are highly sensitive to DNA structure, providing information about conformation changes of the DNA double helix, formation of DNA strand breaks as well as covalent or non-covalent DNA interactions with small molecules (including genotoxic agents, drugs, etc.). Measurements at mercury electrodes allow for determination of small quantities of unmodified or electrochemically labeled nucleic acids. DNA-modified mercury electrodes have been used as biodetectors for DNA damaging agents or as detection electrodes in DNA hybridization assays. Mercury film and solid amalgam electrodes possess similar features in the nucleic acid analysis to mercury drop electrodes. On the contrary, intrinsic (label-free) DNA electrochemical responses at other (non-mercury) solid electrodes cannot provide information about small changes of the DNA structure. A review with 188 references.

A label-free fluorescent molecular beacon based on DNA-Ag nanoclusters for the construction of versatile Biosensors

2015 ◽  
Vol 74 ◽  
pp. 318-321 ◽  
Author(s):  
Qiao Cao ◽  
Ye Teng ◽  
Xuan Yang ◽  
Jin Wang ◽  
Erkang Wang
Keyword(s):  
Molecular Beacon ◽  
Label Free ◽  
Ag Nanoclusters

scholarly journals A one-step and label-free, electrochemical DNA detection using metal ion-mediated molecular beacon probe

2019 ◽  
Vol 100 ◽  
pp. 64-69 ◽  
Author(s):  
Songyi Baek ◽  
Jun Ki Ahn ◽  
Byoung Yeon Won ◽  
Ki Soo Park ◽  
Hyun Gyu Park
Keyword(s):  
Metal Ion ◽  
Molecular Beacon ◽  
Dna Detection ◽  
Label Free ◽  
One Step ◽  
Electrochemical Dna Detection
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