Sorptive thin film microextraction followed by direct solid state spectrofluorimetry: A simple, rapid and sensitive method for determination of carvedilol in human plasma

2016 ◽  
Vol 924 ◽  
pp. 45-52 ◽  
Author(s):  
Shima Karimi ◽  
Zahra Talebpour ◽  
Noushin Adib
Keyword(s):  
Thin Film ◽  
Solid State ◽  
Human Plasma ◽  
Direct Solid ◽  
Sensitive Method

scholarly journals Rapid and Sensitive Method for Quantitative Determination of Lopinavir and Ritonavir in Human Plasma by Liquid Chromatography- Tandem Mass Specrtometry

2009 ◽  
Vol 6 (1) ◽  
pp. 223-230 ◽  
Author(s):  
G. A. Temghare ◽  
S. S. Shetye ◽  
S. S. Joshi
Keyword(s):  
Liquid Chromatography ◽  
Human Plasma ◽  
Solid Phase ◽  
Internal Standard ◽  
Therapeutic Monitoring ◽  
Tandem Mass ◽  
Limit Of Quantification ◽  
Liquid Chromatography Tandem Mass ◽  
Sensitive Method

A rapid and sensitive liquid chromatography-mass spectrometric (LC-MS-MS) method for the simultaneous determination of lopinavir and ritonavir in human plasma using abacavir as internal standard has been developed and validated. Sample preparation of plasma involved solid phase extraction. Detection was performed using an Applied Biosystems Sciex API 2000 Mass spectrometer. The assay of lopinavir and ritonavir was linear over the range of 50 ng mL-1to 20000 ng mL-1and 20 ng mL-1to 3000 ng mL-1 respectively with a precision of <15% and accuracy in the range of 85-115%. The limit of quantification in plasma for lopinavir and ritonavir was 50 ng mL-1and 20 ng mL-1respectively. The described method has the advantage of being rapid and easy and it could be applied in therapeutic monitoring of these drugs in human plasma

scholarly journals Portable solid-state sensor for therapeutic monitoring of an antineoplastic drug; vinblastine in human plasma

RSC Advances ◽  
2020 ◽  
Vol 10 (70) ◽  
pp. 42699-42705
Author(s):  
Maha Mohammed Galal ◽  
Ahmed Sayed Saad
Keyword(s):  
Solid State ◽  
Human Plasma ◽  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Antineoplastic Drug ◽  
Therapeutic Monitoring ◽  
Carbon Electrode ◽  
Solid State Sensor

Potentiometric glassy carbon electrode for determination of vinblastine.

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