scholarly journals Swellable polymer films containing Au nanoparticles for point-of-care therapeutic drug monitoring using surface-enhanced Raman spectroscopy

2016 ◽  
Vol 912 ◽  
pp. 111-116 ◽  
Author(s):  
Wendy W.Y. Lee ◽  
Colin P. McCoy ◽  
Ryan F. Donnelly ◽  
Steven E.J. Bell
Keyword(s):  
Raman Spectroscopy ◽  
Therapeutic Drug Monitoring ◽  
Polymer Films ◽  
Drug Monitoring ◽  
Au Nanoparticles ◽  
Point Of Care ◽  
Surface Enhanced Raman Spectroscopy ◽  
Therapeutic Drug ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

Bacterial detection and differentiation via direct volatile organic compound sensing with surface enhanced Raman spectroscopy

2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Bacterial Infections ◽  
Direct Detection ◽  
Point Of Care ◽  
Surface Enhanced Raman Spectroscopy ◽  
E Coli ◽  
Recent Emergence ◽  
Surface Enhanced ◽  
Volatile Organic ◽  
Surface Enhanced Raman

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.

Morphological evolution of gold nanoparticles on silicon nanowires and their plasmonics

RSC Advances ◽  
2015 ◽  
Vol 5 (61) ◽  
pp. 49708-49718 ◽  
Author(s):  
Yuan Li ◽  
Wenwu Shi ◽  
Aditya Gupta ◽  
Nitin Chopra
Keyword(s):  
Gold Nanoparticles ◽  
Raman Spectroscopy ◽  
Silicon Nanowires ◽  
Au Nanoparticles ◽  
Morphological Evolution ◽  
Surface Enhanced Raman Spectroscopy ◽  
Si Nanowires ◽  
One Dimensional ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

One-dimensional heterostructures composed of silicon (Si) nanowires and uniformly decorated with gold (Au) nanoparticles were fabricated and used as a substrate for organic detection based on the surface-enhanced Raman spectroscopy.

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