Molecularly imprinted polymer coated magnetite nanoparticles as an efficient mefenamic acid resonance light scattering nanosensor

2014 ◽  
Vol 852 ◽  
pp. 250-256 ◽  
Author(s):  
Mazaher Ahmadi ◽  
Tayyebeh Madrakian ◽  
Abbas Afkhami
Keyword(s):  
Light Scattering ◽  
Molecularly Imprinted Polymer ◽  
Magnetite Nanoparticles ◽  
Mefenamic Acid ◽  
Resonance Light Scattering ◽  
Imprinted Polymer ◽  
Molecularly Imprinted

Molecularly Imprinted Polymer-Decorated Magnetite Nanoparticles for Selective Sulfonamide Detection

2016 ◽  
Vol 88 (7) ◽  
pp. 3578-3584 ◽  
Author(s):  
Alejandro Zamora-Gálvez ◽  
Abdellatif Ait-Lahcen ◽  
Luiza A. Mercante ◽  
Eden Morales-Narváez ◽  
Aziz Amine ◽  
...  
Keyword(s):  
Molecularly Imprinted Polymer ◽  
Magnetite Nanoparticles ◽  
Imprinted Polymer ◽  
Molecularly Imprinted

scholarly journals A magnetic molecularly imprinted optical chemical sensor for specific recognition of trace quantities of virus

RSC Advances ◽  
2018 ◽  
Vol 8 (56) ◽  
pp. 32262-32268 ◽  
Author(s):  
Feng Zhang ◽  
Lianghui Luo ◽  
Hang Gong ◽  
Chunyan Chen ◽  
Changqun Cai
Keyword(s):  
Light Scattering ◽  
Magnetic Resonance ◽  
Hepatitis A ◽  
Chemical Sensor ◽  
Hepatitis A Virus ◽  
Resonance Light Scattering ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Optical Chemical Sensor ◽  
Specific Recognition

A magnetic resonance light scattering (RLS) sensor based on the molecularly imprinted polymer (MIP) technique was developed for specific recognition of trace quantities of hepatitis A virus (HAV).

Liquid Chromatography Analysis of Clozapine in Rat Brain Tissue, Using its Molecularly Imprinted Polymer after Administration of Toxic Dose of Drug and Lipid Emulsion Therapy

2019 ◽  
Vol 15 (3) ◽  
pp. 251-257
Author(s):  
Bahareh Sadat Yousefsani ◽  
Seyed Ahmad Mohajeri ◽  
Mohammad Moshiri ◽  
Hossein Hosseinzadeh
Keyword(s):  
Rat Brain ◽  
Brain Tissue ◽  
Molecularly Imprinted Polymer ◽  
Lipid Emulsion ◽  
Limit Of Detection ◽  
Imprinted Polymer ◽  
Toxic Dose ◽  
Molecularly Imprinted ◽  
The Brain ◽  
Rat Brain Tissue

Background:Molecularly imprinted polymers (MIPs) are synthetic polymers that have a selective site for a given analyte, or a group of structurally related compounds, that make them ideal polymers to be used in separation processes.Objective:An optimized molecularly imprinted polymer was selected and applied for selective extraction and analysis of clozapine in rat brain tissue.Methods:A molecularly imprinted solid-phase extraction (MISPE) method was developed for preconcentration and cleanup of clozapine in rat brain samples before HPLC-UV analysis. The extraction and analytical process was calibrated in the range of 0.025-100 ppm. Clozapine recovery in this MISPE process was calculated between 99.40 and 102.96%. The limit of detection (LOD) and the limit of quantification (LOQ) of the assay were 0.003 and 0.025 ppm, respectively. Intra-day precision values for clozapine concentrations of 0.125 and 0.025 ppm were 5.30 and 3.55%, whereas inter-day precision values of these concentrations were 9.23 and 6.15%, respectively. In this study, the effect of lipid emulsion infusion in reducing the brain concentration of drug was also evaluated.Results:The data indicated that calibrated method was successfully applied for the analysis of clozapine in the real rat brain samples after administration of a toxic dose to animal. Finally, the efficacy of lipid emulsion therapy in reducing the brain tissue concentration of clozapine after toxic administration of drug was determined.Conclusion:The proposed MISPE method could be applied in the extraction and preconcentration before HPLC-UV analysis of clozapine in rat brain tissue.

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