Extremely sensitive sandwich assay of kanamycin using surface-enhanced Raman scattering of 2-mercaptobenzothiazole labeled gold@silver nanoparticles

2014 ◽  
Vol 817 ◽  
pp. 33-41 ◽  
Author(s):  
Adem Zengin ◽  
Ugur Tamer ◽  
Tuncer Caykara
Keyword(s):  
Silver Nanoparticles ◽  
Raman Scattering ◽  
Surface Enhanced Raman Scattering ◽  
Sandwich Assay ◽  
Gold Silver ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

Surface-Enhanced Raman Scattering Based on Au-DNA-Ag Plasmonic Nanoparticles

2020 ◽  
Vol 15 (11) ◽  
pp. 1307-1311
Author(s):  
Seyed Enayatollah Taghavi Moghaddam ◽  
Farzin Emami
Keyword(s):  
Silver Nanoparticles ◽  
Raman Scattering ◽  
Surface Enhanced Raman Scattering ◽  
Excitation Wavelength ◽  
Nano Particle ◽  
Gold And Silver Nanoparticles ◽  
Gold Silver ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

The dependence of the Surface-Enhanced Raman Scattering (SERS) by gold and silver nanoparticles on their shape is examined using the organic dye, as a probe molecule. SERS has been explored extensively for applications in sensing and imaging, but the design and optimization of efficient substrates are still challenging. In order to understand and optimize the SERS process in nanoparticles, gold and silver Nanospheres and their composition as gold-DNA-silver nanoparticle were synthesized and characterized according to their average size, zeta potential and UV/visible absorption. In fact, in this research, an asymmetric new plasmonic nano-particle is proposed and designed as gold-DNA-silver and is compared to gold, silver, gold-DNA-gold, and silver-DNA-silver nanoparticles. With the help of this new nanoparticle, we design and recommend a Raman booster so that the effect of Raman is improved noticeably. It will be shown that using the proposed asymmetric nano-particle of gold-DNA-silver, the absorbance, and intensity of Raman booster is improved noticeably. In suspensions of equal nano-particle and dye concentration, the SERS effect increases as gold- DNA-silver, clearly indicating that control over the number of local field hotspots can optimize the SERS efficiency. Notably, it is demonstrated that the SERS intensity per nanoparticle scales with the magnitude of the SPR absorbance at the excitation wavelength (785 nm), providing a clear guide to optimization of the process experimentally.

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