Silver overlayer-modified surface-enhanced Raman scattering-active gold substrates for potential applications in trace detection of biochemical species

2014 ◽  
Vol 806 ◽  
pp. 188-196 ◽  
Author(s):  
Keng-Liang Ou ◽  
Ting-Chu Hsu ◽  
Yu-Chuan Liu ◽  
Kuang-Hsuan Yang ◽  
Hui-Yen Tsai
2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Yu Sun ◽  
Alessio Caravella

This study proposed a facile method to detect metalloporphyrin-based coordination polymer particles (Z-CPPs) in aqueous solution by modified surface-enhanced Raman scattering (SERS). The SERS-active particles are photodeposited on the surface of Z-CPPs, offering an enhanced Raman signal for the trace detection of Z-CPPs.


2009 ◽  
Vol 7 (3) ◽  
pp. 446-453 ◽  
Author(s):  
Mamdouh Abdelsalam

AbstractIn this paper we describe the use of a simple and versatile technique of templated electrodeposition through polystyrene sphere templates to produce nanostructured films of gold with regular submicron spherical holes arranged in a hexagonal close-packed structure. The templates were produced by self assembly of a monodispersed suspension of polystyrene spheres on gold substrates using capillary forces. The self assembly process was modified through the chemical modification of the gold substrate with cysteamine thiol. Films of gold were prepared by electrochemical deposition through the template. The electrochemical deposition charge and the current time curve were used to control the film height with a precision of approximately 10 nm. The colour of the nanostructured films changed as the film thickness was changed. Surface enhanced Raman Scattering spectra were recorded and used to identify very low concentrations of aromatic thiol molecules, 4-Nitrobenzenethiol (4-NBT) and 4-Aminobenzenethiol (4-ABT), adsorbed on the surface of the nanostructured gold substrates.


2015 ◽  
Vol 7 (9) ◽  
pp. 3863-3868 ◽  
Author(s):  
Arniza K. M. Jamil ◽  
Emad L. Izake ◽  
Arumugam Sivanesan ◽  
Roland Agoston ◽  
Godwin A. Ayoko

Extraction and SERS detection of TNT in soil.


2020 ◽  
Vol 74 (11) ◽  
pp. 1374-1383
Author(s):  
Jacob E. Olson ◽  
Adam S. Braegelman ◽  
Lei Zou ◽  
Matthew J. Webber ◽  
Jon P. Camden

The cucurbit[n]uril (CB[ n]) family of macrocycles are known to bind a variety of small molecules with high affinity. These motifs thus have promise in an ever-growing list of trace detection methods. Surface-enhanced Raman scattering (SERS) detection schemes employing CB[ n] motifs exhibit increased sensitivity due to selective concentration of the analyte at the nanoparticle surface, coupled with the ability of CB[ n] to facilitate the formation of well-defined electromagnetic hot spots. Herein, we report a CB[7] SERS assay for quantification of phenylalanine (Phe) and further demonstrate its utility for detecting peptides with an N-terminal Phe. The CB[7]–guest interaction improves the sensitivity 5–25-fold over direct detection of Phe using citrate-capped silver nanoparticle aggregates, enabling use of a portable Raman system. We further illustrate detection of insulin via binding of CB[7] to the N-terminal Phe residue on its B-chain, suggesting a general strategy for detecting Phe-terminated peptides of clinically relevant biomolecules.


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