Nanogold–polyaniline–nanogold microspheres-functionalized molecular tags for sensitive electrochemical immunoassay of thyroid-stimulating hormone

2012 ◽  
Vol 738 ◽  
pp. 76-84 ◽  
Author(s):  
Yuling Cui ◽  
Huafeng Chen ◽  
Li Hou ◽  
Bing Zhang ◽  
Bingqian Liu ◽  
...  
Keyword(s):  
Thyroid Stimulating Hormone ◽  
Electrochemical Immunoassay ◽  
Stimulating Hormone

scholarly journals Detection of TSH, FT3, FT4, and TRAb in ovarian cancer with highly sensitive electrochemical immunoassay

2018 ◽  
Vol 16 ◽  
pp. 205873921879670
Author(s):  
Maoben Yang ◽  
Xiaojun Guo
Keyword(s):  
Ovarian Cancer ◽  
Serum Levels ◽  
Thyroid Stimulating Hormone ◽  
Control Group ◽  
Electrochemical Immunoassay ◽  
Clinical Value ◽  
Free T4 ◽  
Benign Ovarian Tumor ◽  
Highly Sensitive ◽  
Stimulating Hormone

To investigate the correlation between thyroid-stimulating hormone (TSH), free T3 (FT3), free T4 (FT4), thyroid-stimulating hormone receptor antibody (TRAb), and pathological parameters of ovarian cancer, we selected 122 patients with ovarian cancer and 70 patients with benign ovarian tumor. The differences in the positive rates of different pathological parameters, including TSH, FT3, FT4, and TRAb, in their serum were detected and compared through highly sensitive electrochemical immunoassay. We found that the positive rates of TSH, FT3, FT4, and TRAb in serous cystadenocarcinoma were higher than those of mucinous cystadenocarcinoma and other types of ovarian cancer. Meanwhile, the positive rates of FT3 and FT4 in stage III and IV ovarian cancer were lower than those in stage I and II ovarian cancer. However, the positive rates of FT3 and FT4 in poorly differentiated ovarian cancer were higher than those in moderately differentiated and well-differentiated ovarian cancer. The serum levels of TSH, FT3, FT4, and TRAb preoperatively, postoperatively, and after four cycles of ovarian cancer were significantly different from those in the control group. Thus, we conclude that TSH, FT3, FT4, and TRAb were abnormally expressed in the serum of ovarian cancer patients. And the application of highly sensitive electrochemical immunoassay for the detection of TSH, FT3, FT4, and TRAb in serum has important clinical value in the diagnosis of ovarian cancer.

Highly Sensitive ELISA Using Membrane-Based Microwave-Mediated Electrochemical Immunoassay for Thyroid-Stimulating Hormone Detection

2019 ◽  
Vol 19 (21) ◽  
pp. 9826-9831 ◽  
Author(s):  
My Van Tieu ◽  
Anna Go ◽  
Young Ju Park ◽  
Huynh Vu Nguyen ◽  
Sei Young Hwang ◽  
...  
Keyword(s):  
Thyroid Stimulating Hormone ◽  
Electrochemical Immunoassay ◽  
Highly Sensitive ◽  
Stimulating Hormone

CLINICAL EVALUATION OF THE THYROID STIMULATING HORMONE ACTIVITY IN EXOPHTHALMOS

1961 ◽  
Vol 38 (4) ◽  
pp. 577-584 ◽  
Author(s):  
Sven Erik Björkman ◽  
Torsten Denneberg ◽  
Inge Hedenskog
Keyword(s):  
Clinical Evaluation ◽  
Thyroid Stimulating Hormone ◽  
Significant Rise ◽  
Hormone Activity ◽  
Control Subjects ◽  
Long Duration ◽  
Stimulating Factor ◽  
Stimulating Hormone

ABSTRACT A method for demonstrating the presence of a thyroid stimulating factor in the blood of patients with progressive exophthalmos after thyroidectomy or after treatment with radioiodine is described. The method consists of transfusing freshly drawn blood from the patients to euthyroid recipients and subsequently following the PBI level of the recipients at regular intervals. Six exophthalmic patients tested in this manner were found to have such a factor in their circulating blood. After transfusion of their blood a significant rise in the PBI level of the recipients could be demonstrated. Two other patients, one with exophthalmos of long duration did not show this response nor did it occur after transfusion of blood from two control subjects. In one case the action of this factor was compared with that of animal thyrotrophin and found to be of the same magnitude.

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