Quantitative analysis of multiple urinary biomarkers of carcinoid tumors through gold-nanoparticle-assisted laser desorption/ionization time-of-flight mass spectrometry

2011 ◽  
Vol 699 (1) ◽  
pp. 81-86 ◽  
Author(s):  
Tsung-Rong Kuo ◽  
Jinn-Shiun Chen ◽  
Yu-Chen Chiu ◽  
Chia-Yi Tsai ◽  
Cho-Chun Hu ◽  
...  
Author(s):  
Masood Dodangeh ◽  
Hossein Farrokhpour ◽  
Mahmoud Tabrizchi ◽  
Hassan Seyed Ghaziaskar

In the present study, A facile and rapid method of sample preparation for qualitative and quantitative analysis of copper ore by Laser desorption ionization-time of flight mass spectrometry (LDI-TOF-MS) is...


2000 ◽  
Vol 66 (11) ◽  
pp. 4720-4724 ◽  
Author(s):  
Matthew L. Magnuson ◽  
James H. Owens ◽  
Catherine A. Kelty

ABSTRACT Matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) was used to investigate whole and freeze-thawed Cryptosporidium parvum oocysts. Whole oocysts revealed some mass spectral features. Reproducible patterns of spectral markers and increased sensitivity were obtained after the oocysts were lysed with a freeze-thaw procedure. Spectral-marker patterns forC. parvum were distinguishable from those obtained forCryptosporidium muris. One spectral marker appears specific for the genus, while others appear specific at the species level. Three different C. parvum lots were investigated, and similar spectral markers were observed in each. Disinfection of the oocysts reduced and/or eliminated the patterns of spectral markers.


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