Detection of anabolic androgenic steroid abuse in doping control using mammalian reporter gene bioassays

2009 ◽  
Vol 637 (1-2) ◽  
pp. 247-258 ◽  
Author(s):  
Corine J. Houtman ◽  
Saskia S. Sterk ◽  
Monique P.M. van de Heijning ◽  
Abraham Brouwer ◽  
Rainer W. Stephany ◽  
...  
Keyword(s):  
Reporter Gene ◽  
Doping Control ◽  
Anabolic Androgenic Steroid ◽  
Steroid Abuse ◽  
Androgenic Steroid ◽  
In Doping

scholarly journals Doping practices in international weightlifting: analysis of sanctioned athletes/support personnel from 2008 to 2019 and retesting of samples from the 2008 and 2012 Olympic Games

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Alexander Kolliari-Turner ◽  
Brian Oliver ◽  
Giscard Lima ◽  
John P. Mills ◽  
Guan Wang ◽  
...  
Keyword(s):  
Sensitivity And Specificity ◽  
Regional Differences ◽  
Olympic Games ◽  
Anabolic Androgenic Steroid ◽  
Sample Storage ◽  
Support Personnel ◽  
Androgenic Steroid ◽  
In Doping ◽  
Targeted Testing

Abstract Background The pervasiveness of doping and findings of anti-doping corruption threaten weightlifting’s position at the 2024 Olympic Games. Analysing the practices of doping in weightlifters could identify patterns in doping that assist in future detection. Methods We analysed publicly available data on sanctioned athletes/support personnel from the International Weightlifting Federation between 2008 and 2019 and announced retrospective Anti-Doping Rule Violations (ADRVs) from the 2008 and 2012 Olympic Games. Results There were 565 sanctions between 2008 and 2019 of which 82% related to the detection of exogenous Anabolic Androgenic Steroid (AAS) metabolites and markers indicating endogenous AAS usage. The detection of exogenous AAS metabolites, markers of endogenous AAS usage and other substance metabolites varied by IWF Continental Federation (p ≤ 0.05) with Europe (74%, 11%, 15%) and Asia (70%, 15%, 15%) showing a higher detection of exogenous AAS compared to Pan America (37%, 30%, 33%) and Africa (50%, 17%, 33%). When looking at the 10 most detected substances, the nations with the highest number of sanctions (range 17–35) all had at least one overrepresented substance that accounted for 38–60% of all detected substances. The targeted re-analysis of samples from the 2008 and 2012 Olympic Games due to the discovery of long-term metabolites for exogenous AAS resulted in 61 weightlifters producing retrospective ADRVs. This includes 34 original medallists (9 gold, 10 silver and 15 bronze), the highest of any sport identified by Olympic Games sample re-testing. The exogenous AAS dehydrochloromethyltestosterone and stanozolol accounted for 83% of detected substances and were present in 95% of these samples. Conclusion Based on these findings of regional differences in doping practices, weightlifting would benefit from the targeted testing of certain regions and continuing investment in long-term sample storage as the sensitivity and specificity of detection continues to improve.

Prolonged impairment of sexual function associated with anabolic–androgenic steroid abuse: An underrecognized problem

2014 ◽  
Vol 94 (2) ◽  
pp. 237
Author(s):  
Harrison G. Pope ◽  
Gen Kanayama ◽  
James I. Hudson ◽  
James DeLuca ◽  
Stephanie Isaacs ◽  
...  
Keyword(s):  
Sexual Function ◽  
Anabolic Androgenic Steroid ◽  
Steroid Abuse ◽  
Androgenic Steroid

ANABOLIC-ANDROGENIC STEROID ABUSE AND PSYCHOPATHOLOGY

1998 ◽  
Vol 21 (4) ◽  
pp. 829-833 ◽  
Author(s):  
John H. Porcerelli ◽  
Bruce A. Sandler
Keyword(s):  
Anabolic Androgenic Steroid ◽  
Steroid Abuse ◽  
Androgenic Steroid

Anabolic-Androgenic steroid abuse in weight lifters: Evidence for activation of the hemostatic system

1995 ◽  
Vol 49 (4) ◽  
pp. 282-288 ◽  
Author(s):  
Gary S. Ferenchick ◽  
Shinchirou Hirokawa ◽  
Eberhard F. Mammen ◽  
Kenneth A. Schwartz
Keyword(s):  
Anabolic Androgenic Steroid ◽  
Steroid Abuse ◽  
Androgenic Steroid ◽  
Hemostatic System ◽  
Weight Lifters

Immunodeficiency as a side effect of anabolic androgenic steroid abuse: a case of necrotizing myofasciitis

2019 ◽  
Vol 15 (4) ◽  
pp. 616-621 ◽  
Author(s):  
Giuseppe Bertozzi ◽  
Francesco Sessa ◽  
Francesca Maglietta ◽  
Luigi Cipolloni ◽  
Monica Salerno ◽  
...  
Keyword(s):  
Side Effect ◽  
Anabolic Androgenic Steroid ◽  
Steroid Abuse ◽  
Androgenic Steroid

Misconceptions About Anabolic-Androgenic Steroid Abuse

2012 ◽  
Vol 42 (10) ◽  
pp. 371-375 ◽  
Author(s):  
Gen Kanayama ◽  
Harrison G. Pope
Keyword(s):  
Anabolic Androgenic Steroid ◽  
Steroid Abuse ◽  
Androgenic Steroid
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