Simultaneous liquid chromatographic determination of metals and organic compounds in pharmaceutical and food-supplement formulations using evaporative light scattering detection

2007 ◽  
Vol 583 (2) ◽  
pp. 239-245 ◽  
Author(s):  
Zdenek Spacil ◽  
Jana Folbrova ◽  
Nikolaos Megoulas ◽  
Petr Solich ◽  
Michael Koupparis
Keyword(s):  
Light Scattering ◽  
Organic Compounds ◽  
Chromatographic Determination ◽  
Food Supplement ◽  
Evaporative Light Scattering Detection ◽  
Light Scattering Detection ◽  
Evaporative Light Scattering ◽  
Liquid Chromatographic Determination ◽  
Liquid Chromatographic

scholarly journals Determination of Ginsenosides in Panax ginseng Roots by Liquid Chromatography with Evaporative Light-Scattering Detection

2000 ◽  
Vol 83 (4) ◽  
pp. 820-829 ◽  
Author(s):  
Nicola Fuzzati ◽  
Bruno Gabetta ◽  
Kaishik Jayakar ◽  
Roberto Pace ◽  
Giuseppe Ramaschi ◽  
...  
Keyword(s):  
Liquid Chromatography ◽  
Light Scattering ◽  
Panax Ginseng ◽  
Reversed Phase ◽  
Evaporative Light Scattering Detection ◽  
Intermediate Precision ◽  
Light Scattering Detection ◽  
Evaporative Light Scattering ◽  
Liquid Chromatographic

Abstract A liquid chromatographic method was developed and validated for the determination of ginsenosides in Panax ginseng roots by using evaporative light-scattering detection. Eighteen ginsenosides were separated on a reversed-phase C18 column with water–ammonium acetate–acetonitrile as the mobile phase. The method is suitable for the routine determination of ginsenosides in P. ginseng roots and extracts. The validation of the method was comprehensive for efficiency and recovery optimization of the P. ginseng roots extraction, specificity by liquid chromatography/mass spectrometry, linearity, stability, reproducibility, repeatability, intermediate precision, and robustness.

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