Impedance immunosensor based on receptor protein adsorbed directly on porous gold film

2005 ◽  
Vol 553 (1-2) ◽  
pp. 190-195 ◽  
Author(s):  
Zhaopeng Chen ◽  
Jianhui Jiang ◽  
Guoli Shen ◽  
Ruqin Yu
Keyword(s):  
Gold Film ◽  
Receptor Protein ◽  
Porous Gold ◽  
Porous Gold Film ◽  
Impedance Immunosensor

scholarly journals Simple Fabrication of Porous Gold-Film Electrodes and Their Electroanalytical Applications

2010 ◽  
Vol 26 (1) ◽  
pp. 129-132 ◽  
Author(s):  
Myeounghee HYUN ◽  
Suhee CHOI ◽  
Jongwon KIM
Keyword(s):  
Gold Film ◽  
Porous Gold ◽  
Porous Gold Film

scholarly journals Surface Acoustic Wave Biosensor with Laser-Deposited Gold Layer Having Controlled Porosity

Chemosensors ◽  
2021 ◽  
Vol 9 (7) ◽  
pp. 173
Author(s):  
Dana Miu ◽  
Izabela Constantinoiu ◽  
Valentina Dinca ◽  
Cristian Viespe
Keyword(s):  
Acoustic Wave ◽  
Surface Acoustic Wave ◽  
Gold Film ◽  
Good Control ◽  
Gold Layer ◽  
Porous Gold ◽  
Deposition Parameters ◽  
Acoustic Wave Sensors ◽  
Controlled Porosity ◽  
Wave Sensors

Laser-deposited gold immobilization layers having different porosities were incorporated into love wave surface acoustic wave sensors (LW-SAWs). Variation of pulsed laser deposition parameters allows good control of the gold film morphology. Biosensors with various gold film porosities were tested using the biotin–avidin reaction. Control of the Au layer morphology is important since the biotin and avidin layer morphologies closely follow that of the gold. The response of the sensors to biotin/avidin, which is a good indicator of biosensor performance, is improved when the gold layer has increased porosity. Given the sizes of the proteins, the laser-deposited porous gold interfaces have optimal pore dimensions to ensure protein stability.

Semiconductor Nanostructures defined by self-organizing Polymers

2002 ◽  
Vol 728 ◽  
Author(s):  
Michael Haupt ◽  
Stephan Miller ◽  
Andreas Ladenburger ◽  
Rolf Sauer ◽  
Klaus Thonke ◽  
...  
Keyword(s):  
Diblock Copolymers ◽  
Gold Film ◽  
Metal Cluster ◽  
Hydrogen Plasma ◽  
Dry Etching ◽  
Porous Gold ◽  
Total Analysis System ◽  
Image Reversal ◽  
Analysis System ◽  
Lithographic Masks

AbstractIn the near future it will be more and more important to produce real nanometer-sized structures for semiconductor devices (e.g., quantum dot lasers) but also for nano-biomechanical applications like the so-called total analysis system implemented on one chip.We describe here a technique to create nanometer-sized structures in semiconductors and metals by the use of self-assembling diblock copolymers as nano-lithographic masks. Semiconductor quantum structures with very high aspect ratio of 1:10 were fabricated from III-V semiconductor heterostructures by anisotropic dry etching. In a first step, so-called diblock copolymer micelles were generated in a toluene solution. These micelles were loaded by a noblemetal salt. With a “Langmuir Blodgett” technique we can decorate complete wafers with a monolayer of highly ordered micelles, covering almost the complete surface. After treatment in a hydrogen plasma all of the organic components are removed and only crystalline metal clusters of ~12 nm size remain. This metal cluster mask can be used directly in a highly anisotropic chlorine dry etching process to etch cylinders in GaAs and its In and Al alloys. It is also possible to etch through a quantum well layer underneath the surface in order to produce quantum dots.By evaporating metals and applying a wet chemical image reversal process, we can invert the etched structure and generate a gauzy gold film with nano-holes inside. It is thinkable to use this porous gold film as a nano-filter in upcoming nano-biotechnology applications.

scholarly journals Fabrication of Porous Gold Film Using Graphene Oxide as a Sacrificial Layer

Materials ◽  
2019 ◽  
Vol 12 (14) ◽  
pp. 2305 ◽  
Author(s):  
Alazzam ◽  
Alamoodi ◽  
Abutayeh ◽  
Stiharu ◽  
Nerguizian
Keyword(s):  
Graphene Oxide ◽  
Oxide Layer ◽  
Gold Film ◽  
Porous Metal ◽  
Metal Films ◽  
Porous Electrodes ◽  
Fabrication Process ◽  
Etching Time ◽  
Oxide Dispersion ◽  
Porous Gold

An original and simple fabrication process to produce thin porous metal films on selected substrates is reported. The fabrication process includes the deposition of a thin layer of gold on a substrate, spin coating of a graphene oxide dispersion, etching the gold film through the graphene oxide layer, and removing the graphene oxide layer. The porosity of the thin gold film is controlled by varying the etching time, the thickness of the gold film, and the concentration of the graphene oxide dispersion. Images by scanning electron and metallurgical microscopes show a continuous gold film with random porosity formed on the substrate with a porosity size ranging between hundreds of nanometers to tens of micrometers. This general approach enables the fabrication of porous metal films using conventional microfabrication techniques. The proposed process is implemented to fabricate electrodes with patterned porosity that are used in a microfluidic system to manipulate living cells under dielectrophoresis. Porous electrodes are found to enhance the magnitude and spatial distribution of the dielectrophoretic force.

scholarly journals Porous Gold Films Fabricated by Wet-Chemistry Processes

2016 ◽  
Vol 2016 ◽  
pp. 1-9
Author(s):  
Aymeric Pastre ◽  
Odile Cristini ◽  
Alexandre Boe ◽  
Katarzyna Raulin ◽  
Bertrand Grimbert ◽  
...  
Keyword(s):  
Electroless Deposition ◽  
Film Growth ◽  
Gold Film ◽  
Dip Coating ◽  
Gold Films ◽  
Covalent Bonds ◽  
Wet Chemistry ◽  
Porous Gold ◽  
Wide Range ◽  
20 Nm

Porous gold films presented in this paper are formed by combining gold electroless deposition and polystyrene beads templating methods. This original approach allows the formation of conductive films (2 × 106 (Ω·cm)−1) with tailored and interconnected porosity. The porous gold film was deposited up to 1.2 μm on the silicon substrate without delamination. An original zirconia gel matrix containing gold nanoparticles deposited on the substrate acts both as an adhesion layer through the creation of covalent bonds and as a seed layer for the metallic gold film growth. Dip-coating parameters and gold electroless deposition kinetics have been optimized in order to create a three-dimensional network of 20 nm wide pores separated by 20 nm thick continuous gold layers. The resulting porous gold films were characterized by GIXRD, SEM, krypton adsorption-desorption, and 4-point probes method. The process is adaptable to different pore sizes and based on wet-chemistry. Consequently, the porous gold films presented in this paper can be used in a wide range of applications such as sensing, catalysis, optics, or electronics.

Electrochemical Impedance Immunosensor Based on Three-Dimensionally Ordered Macroporous Gold Film

2008 ◽  
Vol 80 (6) ◽  
pp. 2133-2140 ◽  
Author(s):  
Xiaojun Chen ◽  
Yuanyuan Wang ◽  
Jinjun Zhou ◽  
Wei Yan ◽  
Xinghua Li ◽  
...  
Keyword(s):  
Gold Film ◽  
Electrochemical Impedance ◽  
Ordered Macroporous ◽  
Impedance Immunosensor

Contrast from epitaxially sandwiched macromolecules

1978 ◽  
Vol 36 (2) ◽  
pp. 226-227
Author(s):  
M. Talianker ◽  
D.G. Brandon
Keyword(s):  
Gold Film ◽  
Lattice Defect ◽  
Gold Foil ◽  
Specimen Preparation ◽  
Preparation Technique ◽  
Resolution Limit ◽  
Transmission Electron ◽  
Crystal Lattice Defect ◽  
Void Effect ◽  
Lattice Resolution

A new specimen preparation technique for visualizing macromolecules by conventional transmission electron microscopy has been developed. In this technique the biopolymer-molecule is embedded in a thin monocrystalline gold foil. Such embedding can be performed in the following way: the biopolymer is deposited on an epitaxially-grown thin single-crystal gold film. The molecule is then occluded by further epitaxial growth. In such an epitaxial sandwich an occluded molecule is expected to behave as a crystal-lattice defect and give rise to contrast in the electron microscope.The resolution of the method should be limited only by the precision with which the epitaxially grown gold reflects the details of the molecular structure and, in favorable cases, can approach the lattice resolution limit.In order to estimate the strength of the contrast due to the void-effect arising from occlusion of the DNA-molecule in a gold crystal some calculations were performed.

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