Manganese ions induce H2O2 generation at the ubiquinone binding site of mitochondrial complex II

2015 ◽  
Vol 580 ◽  
pp. 75-83 ◽  
Author(s):  
Erik Bonke ◽  
Klaus Zwicker ◽  
Stefan Dröse
Keyword(s):  
Binding Site ◽  
Manganese Ions ◽  
Mitochondrial Complex ◽  
Complex Ii ◽  
H2o2 Generation ◽  
Ubiquinone Binding

scholarly journals Ubiquinone-binding site mutagenesis reveals the role of mitochondrial complex II in cell death initiation

2015 ◽  
Vol 6 (5) ◽  
pp. e1749-e1749 ◽  
Author(s):  
K Kluckova ◽  
M Sticha ◽  
J Cerny ◽  
T Mracek ◽  
L Dong ◽  
...  
Keyword(s):  
Cell Death ◽  
Binding Site ◽  
Mitochondrial Complex ◽  
Complex Ii ◽  
Site Mutagenesis ◽  
Ubiquinone Binding

scholarly journals Inhibitors of ROS production by the ubiquinone-binding site of mitochondrial complex I identified by chemical screening

2013 ◽  
Vol 65 ◽  
pp. 1047-1059 ◽  
Author(s):  
Adam L. Orr ◽  
Deepthi Ashok ◽  
Melissa R. Sarantos ◽  
Tong Shi ◽  
Robert E. Hughes ◽  
...  
Keyword(s):  
Binding Site ◽  
Complex I ◽  
Mitochondrial Complex I ◽  
Ros Production ◽  
Mitochondrial Complex ◽  
Chemical Screening ◽  
Ubiquinone Binding

scholarly journals Exome sequencing identifies NFS 1 deficiency in a novel Fe‐S cluster disease, infantile mitochondrial complex II / III deficiency

2013 ◽  
Vol 2 (1) ◽  
pp. 73-80 ◽  
Author(s):  
Sali M. K. Farhan ◽  
Jian Wang ◽  
John F. Robinson ◽  
Piya Lahiry ◽  
Victoria M. Siu ◽  
...  
Keyword(s):  
Exome Sequencing ◽  
Mitochondrial Complex ◽  
Complex Ii

Discovery of 1,2,4-triazole-1,3-disulfonamides as dual inhibitors of mitochondrial complex II and complex III

2015 ◽  
Vol 39 (9) ◽  
pp. 7281-7292 ◽  
Author(s):  
Hua Cheng ◽  
Yan-Qing Shen ◽  
Xia-Yan Pan ◽  
Yi-Ping Hou ◽  
Qiong-You Wu ◽  
...  
Keyword(s):  
Complex Iii ◽  
Dual Function ◽  
Mitochondrial Complex ◽  
Complex Ii ◽  
Dual Inhibitors

1,2,4-Triazole-1,3-disulfonamide derivatives as dual function inhibitors of mitochondrial complex II (SQR) and complex III (cyt bc1) were discovered.

Sign in / Sign up

Export Citation Format

Share Document