Antioxidant defense in hibernation: Cloning and expression of peroxiredoxins from hibernating ground squirrels, Spermophilus tridecemlineatus

2007 ◽  
Vol 461 (1) ◽  
pp. 59-65 ◽  
Author(s):  
Pier Jr Morin ◽  
Kenneth B. Storey
Keyword(s):  
Antioxidant Defense ◽  
Ground Squirrels ◽  
Cloning And Expression ◽  
Spermophilus Tridecemlineatus

scholarly journals Circulation and metabolic rates in a natural hibernator: an integrative physiological model

2010 ◽  
Vol 299 (6) ◽  
pp. R1478-R1488 ◽  
Author(s):  
Marshall Hampton ◽  
Bethany T. Nelson ◽  
Matthew T. Andrews
Keyword(s):  
Body Temperature ◽  
Metabolic Rate ◽  
Core Body Temperature ◽  
Circulatory System ◽  
Physiological Model ◽  
Ground Squirrels ◽  
Metabolic Rates ◽  
Spermophilus Tridecemlineatus ◽  
Brown Adipose ◽  
Core Body

Small hibernating mammals show regular oscillations in their heart rate and body temperature throughout the winter. Long periods of torpor are abruptly interrupted by arousals with heart rates that rapidly increase from 5 beats/min to over 400 beats/min and body temperatures that increase by ∼30°C only to drop back into the hypothermic torpid state within hours. Surgically implanted transmitters were used to obtain high-resolution electrocardiogram and body temperature data from hibernating thirteen-lined ground squirrels ( Spermophilus tridecemlineatus ). These data were used to construct a model of the circulatory system to gain greater understanding of these rapid and extreme changes in physiology. Our model provides estimates of metabolic rates during the torpor-arousal cycles in different model compartments that would be difficult to measure directly. In the compartment that models the more metabolically active tissues and organs (heart, brain, liver, and brown adipose tissue) the peak metabolic rate occurs at a core body temperature of 19°C approximately midway through an arousal. The peak metabolic rate of the active tissues is nine times the normothermic rate after the arousal is complete. For the overall metabolic rate in all tissues, the peak-to-resting ratio is five. This value is high for a rodent, which provides evidence for the hypothesis that the arousal from torpor is limited by the capabilities of the cardiovascular system.

Expression of Nrf2 and its downstream gene targets in hibernating 13-lined ground squirrels, Spermophilus tridecemlineatus

2008 ◽  
Vol 312 (1-2) ◽  
pp. 121-129 ◽  
Author(s):  
Pier Jr Morin ◽  
Zhouli Ni ◽  
David C. McMullen ◽  
Kenneth B. Storey
Keyword(s):  
Ground Squirrels ◽  
Spermophilus Tridecemlineatus

Helminth parasites of squirrels (Sciuridae) in Saskatchewan

1980 ◽  
Vol 58 (11) ◽  
pp. 2040-2050 ◽  
Author(s):  
Steven G. McGee
Keyword(s):  
Ground Squirrels ◽  
Tamiasciurus Hudsonicus ◽  
Glaucomys Sabrinus ◽  
Helminth Parasites ◽  
Spermophilus Tridecemlineatus ◽  
New Host ◽  
Marmota Monax ◽  
The Family ◽  
Spermophilus Franklinii ◽  
New Host Records

During the period March 1976 to November 1977, 377 mammals of the family Sciuridae (Rodentia) were collected in Saskatchewan and examined for helminths. Species and numbers of each were as follows: Spermophilus richardsonii (Sabine), 209; Spermophilus franklinii (Sabine), 46; Spermophilus tridecemlineatus (Mitchill), 31; Tamiasciurus hudsonicus (A. H. Howell), 64; Glaucomys sabrinus (Shaw), 12; Eutamias minimus (J. A. Allen), 11; and Marmota monax (Erxleben), 4.Ten species of cestodes, 2 species of trematodes, 11 species of nematodes, and 1 acanthocephalan were represented in the collections made. New host records and (or) geographic range extensions were indicated for 10 species of helminths.In addition to taxonomic considerations of the helminths, attention has been given to parasite–host relationships involving ground squirrels. In general, male Spermophilus spp. were significantly more commonly infected than were females, and older squirrels were significantly more commonly infected than were younger ones. However, adult squirrels did not have significantly more worms than did juveniles.

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