Label-enhanced surface plasmon resonance applied to label-free interaction analysis of small molecules and fragments

2016 ◽  
Vol 510 ◽  
pp. 79-87 ◽  
Author(s):  
Lars Eng ◽  
Linnéa Nygren-Babol ◽  
Anders Hanning
Keyword(s):  
Surface Plasmon Resonance ◽  
Small Molecules ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Interaction Analysis ◽  
Label Free ◽  
Free Interaction ◽  
Enhanced Surface

Surface Plasmon Resonance enhanced Common Path Interferometry for high sensitivity label free biomolecule interaction analysis

2007 ◽  
Author(s):  
Charles Greef ◽  
Viatcheslav Petropavlovskikh ◽  
Oyvind Nilsen ◽  
Bilge Hacioglu ◽  
Boris Khattatov ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Interaction Analysis ◽  
High Sensitivity ◽  
Label Free ◽  
Common Path

scholarly journals Lasing Enhanced Surface Plasmon Resonance Sensing

Nanophotonics ◽  
2017 ◽  
Vol 6 (2) ◽  
pp. 472-478 ◽  
Author(s):  
Xing-Yuan Wang ◽  
Yi-Lun Wang ◽  
Suo Wang ◽  
Bo Li ◽  
Xiao-Wei Zhang ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Optical Sensors ◽  
Plasmon Resonance ◽  
Refractive Index Sensor ◽  
Label Free ◽  
Plasmonic Sensors ◽  
Biochemical Sensing ◽  
Enhanced Surface ◽  
Intensity Sensing

AbstractThe resonance phenomena of surface plasmons has enabled development of a novel class of noncontact, real-time and label-free optical sensors, which have emerged as a prominent tool in biochemical sensing and detection. However, various forms of surface plasmon resonances occur with natively strong non-radiative Drude damping that weakens the resonance and limits the sensing performance fundamentally. Here we experimentally demonstrate the first lasing-enhanced surface plasmon resonance (LESPR) refractive index sensor. The figure of merit (FOM) of intensity sensing is ~84,000, which is about 400 times higher than state-of-the-art surface plasmon resonance (SPR) sensor. We found that the high FOM originates from three unique features of LESPR sensors: high-quality factor, nearly zero background emission and the Gaussian-shaped lasing spectra. The LESPR sensors may form the basis for a novel class of plasmonic sensors with unprecedented performance for a broad range of applications.

Plasma enhanced label-free immunoassay for alpha-fetoprotein based on a U-bend fiber-optic LSPR biosensor

RSC Advances ◽  
2015 ◽  
Vol 5 (31) ◽  
pp. 23990-23998 ◽  
Author(s):  
Gaoling Liang ◽  
Zhongjun Zhao ◽  
Yin Wei ◽  
Kunping Liu ◽  
Wenqian Hou ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Localized Surface Plasmon Resonance ◽  
Fiber Optic ◽  
Cost Effective ◽  
Alpha Fetoprotein ◽  
Localized Surface Plasmon ◽  
Label Free

A simple, label-free and cost-effective localized surface plasmon resonance (LSPR) immunosensing method was developed for detection of alpha-fetoprotein (AFP).

scholarly journals Modifications of the PAMONO-Sensor Help to Size and Quantify Low Number of Individual Biological and Non-Biological Nano-Particles

2021 ◽  
Vol 6 (1) ◽  
pp. 26
Author(s):  
Rahat Morad Talukder ◽  
Al Shahriar Hossain Rakib ◽  
Julija Skolnik ◽  
Zohair Usfoor ◽  
Katharina Kaufmann ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Nano Particles ◽  
Label Free ◽  
Specific Detection ◽  
Virus Like Particles ◽  
Low Concentrations ◽  
Challenging Tasks ◽  
Image Area

In a series of recently published works, we demonstrated that the plasmon-assisted microscopy of nano-objects (PAMONO) technique can be successfully employed for the sizing and quantification of single viruses, virus-like particles, microvesicles and charged non-biological particles. This approach enables label-free, but specific detection of biological nano-vesicles. Hence, the sensor, which was built up utilizing plasmon-assisted microscopy, possesses relative versatility and it can be used as a platform for cell-based assays. However, one of the challenging tasks for such a sensor was the ability to reach a homogeneous illumination of the whole surface of the gold sensor slide. Moreover, in order to enable the detection of even relatively low concentrations of nano-particles, the focused image area had to be expanded. Both tasks were solved via modifications of previously described PAMONO-sensor set ups. Taken together, our latest findings can help to develop a research and diagnostic platform based on the principles of the surface plasmon resonance (SPR)-assisted microscopy of nano-objects.

scholarly journals Highly enhanced surface plasmon resonance in a coupled silver nanodumbbell

2011 ◽  
Vol 104 (3) ◽  
pp. 801-805 ◽  
Author(s):  
Yuan-Fong Chau ◽  
Min Wei Chen ◽  
Han-Hsuan Yeh ◽  
Fong-Lin Wu ◽  
Huang-Yi Li ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Enhanced Surface
Sign in / Sign up

Export Citation Format

Share Document