Mass spectrometric analysis of affinity-captured proteins on a dendrimer-based immunosensing surface: investigation of on-chip proteolytic digestion

2005 ◽  
Vol 337 (2) ◽  
pp. 294-307 ◽  
Author(s):  
Hak-Joon Seok ◽  
Mi-Young Hong ◽  
Young-Ja Kim ◽  
Min-Kyu Han ◽  
Dohoon Lee ◽  
...  
Nanoscale ◽  
2016 ◽  
Vol 8 (3) ◽  
pp. 1665-1675 ◽  
Author(s):  
Samuel S. Hinman ◽  
Chih-Yuan Chen ◽  
Jicheng Duan ◽  
Quan Cheng

Patterned gold nanoparticle microarrays, with a nanoscale silicate coating, have been developed for on-chip, high-throughput mass spectrometric analysis of biomolecules.


Author(s):  
Raphael D. Urban ◽  
Tillmann G. Fischer ◽  
Ales Charvat ◽  
Konstantin Wink ◽  
Benjamin Krafft ◽  
...  

AbstractBy the on-chip integration of a droplet generator in front of an emitter tip, droplets of non-polar solvents are generated in a free jet of an aqueous matrix. When an IR laser irradiates this free liquid jet consisting of water as the continuous phase and the non-polar solvent as the dispersed droplet phase, the solutes in the droplets are ionized. This ionization at atmospheric pressure enables the mass spectrometric analysis of non-polar compounds with the aid of a surrounding aqueous matrix that absorbs IR light. This works both for non-polar solvents such as n-heptane and for water non-miscible solvents like chloroform. In a proof of concept study, this approach is applied to monitor a photooxidation of N-phenyl-1,2,3,4-tetrahydroisoquinoline. Graphical abstract


2019 ◽  
Vol 9 (3) ◽  
pp. 161
Author(s):  
Sung-Eun Cho ◽  
Hyojin Chae ◽  
Hyung-Doo Park ◽  
Sail Chun ◽  
Yong-Wha Lee ◽  
...  

2015 ◽  
Vol 60 (6) ◽  
pp. 511-520 ◽  
Author(s):  
A.A. Efremov ◽  
◽  
V.G. Litovchenko ◽  
V.P. Melnik ◽  
O.S. Oberemok ◽  
...  

2002 ◽  
Vol 75 (3) ◽  
pp. 316 ◽  
Author(s):  
Zsolt Ablonczy ◽  
Patrice Goletz ◽  
Daniel R. Knapp ◽  
Rosalie K. Crouch

Sign in / Sign up

Export Citation Format

Share Document