Multiplexed fluorescence detection in microfabricated devices with both time-resolved and spectral-discrimination capabilities using near-infrared fluorescence

2004 ◽  
Vol 330 (2) ◽  
pp. 206-218 ◽  
Author(s):  
Li Zhu ◽  
Wieslaw J Stryjewski ◽  
Steven A Soper
Keyword(s):  
Fluorescence Detection ◽  
Near Infrared ◽  
Time Resolved ◽  
Near Infrared Fluorescence ◽  
Spectral Discrimination ◽  
Microfabricated Devices

A Novel Near-Infrared Fluorescence Sensor for H2O2 Based on N-Acetyl-L-Cysteine-Capped Gold Nanoparticles

2017 ◽  
Vol 46 ◽  
pp. 234-240
Author(s):  
Wen Juan Dong ◽  
Ji Yan Han ◽  
Xin Wu ◽  
Li Fan ◽  
Wen Ting Liang
Keyword(s):  
Hydrogen Peroxide ◽  
Gold Nanoparticles ◽  
Fluorescence Quenching ◽  
Near Infrared ◽  
Fluorescence Probe ◽  
Fluorescence Emission ◽  
Excitation Wavelength ◽  
Experimental Conditions ◽  
Time Resolved ◽  
Near Infrared Fluorescence

A novel near-infrared fluorescence quenching method has been developed for the determination of hydrogen peroxide based on N-acetyl-L-cysteine-capped gold nanoparticles (NAC-AuNPs) as a fluorescence probe. The prepared gold nanoparticles with the size of about 1.91 nm exhibited strong near-infrared fluorescence emission at 693 nm with excitation wavelength at 450 nm in aqueous solution. The fluorescence intensity of NAC-AuNPs was quenched dramatically by adding hydrogen peroxide. Therefore, it could be used to detect hydrogen peroxide based on the fluorescence quenching intensity was linear with the concentration of hydrogen peroxide. Under the optimal experimental conditions, the linear range and detection limit were 1.0×10-6 –3.0×10-2 mol/L and 1.0×10-7 mol/L, respectively. The possible quenching mechanism was investigated by time-resolved fluorescence spectroscopy. The proposed method was simple, sensitive and showed good repeatability and stability.

Augmented microscopy with near-infrared fluorescence detection

2015 ◽  
Author(s):  
Jeffrey R. Watson ◽  
Nikolay Martirosyan ◽  
Jesse Skoch ◽  
G. Michael Lemole ◽  
Rein Anton ◽  
...  
Keyword(s):  
Fluorescence Detection ◽  
Near Infrared ◽  
Near Infrared Fluorescence

Efficient near infrared fluorescence detection of elastase enzyme using peptide-bound unsymmetrical squaraine dye

2017 ◽  
Vol 27 (17) ◽  
pp. 4024-4029 ◽  
Author(s):  
Maryala Saikiran ◽  
Daisuke Sato ◽  
Shyam S. Pandey ◽  
Shuzi Hayase ◽  
Tamaki Kato
Keyword(s):  
Fluorescence Detection ◽  
Near Infrared ◽  
Near Infrared Fluorescence ◽  
Squaraine Dye

Probing trace Hg2+ in a microfluidic chip coupled with in situ near-infrared fluorescence detection

Talanta ◽  
2013 ◽  
Vol 114 ◽  
pp. 204-210 ◽  
Author(s):  
Jiaqin Wang ◽  
Hui Chen ◽  
Peng Zhang ◽  
Zhengyong Zhang ◽  
Song Zhang ◽  
...  
Keyword(s):  
Fluorescence Detection ◽  
Microfluidic Chip ◽  
Near Infrared ◽  
Near Infrared Fluorescence
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