Microfluidic Systems for High-Throughput Screening

2011 ◽  
Keyword(s):  
High Throughput ◽  
High Throughput Screening ◽  
Microfluidic Systems

An Ultra-High-Throughput Flow-Focusing Microfluidic Device for Creation of Liquid Droplets in Air

2017 ◽  
Author(s):  
Pooyan Tirandazi ◽  
Gabriel Tomic ◽  
Carlos H. Hidrovo
Keyword(s):  
High Throughput ◽  
High Throughput Screening ◽  
High Speed ◽  
Large Scale ◽  
3D Structure ◽  
Scale Production ◽  
Liquid Droplets ◽  
Flow Focusing ◽  
Microfluidic Systems ◽  
Uniform Array

In this paper a new microfluidic technique is proposed for ultra-high-throughput generation of micron-sized water droplets using a high-speed air. We use a 3D flow-focusing microchannel fabricated in PDMS by multilayer lithography process. The interaction of liquid and gas created three main flow conditions which are: Flooded, Dripping, and Jetting. We characterize the Jetting regime where a capillary jet surrounded by the air breaks up into uniform array of droplets. Frequency of generation and droplet size are reported for the jetting regime under different liquid and gas flows. It was possible to obtain 25μm diameter droplets and much higher frequencies (f≈120 kHz) compared to the state-of-the-art microfluidic systems. We believe the advantages of this platform enables many novel applications such as high-throughput screening of airborne targets and large-scale production of oil-free particles. The 3D structure of this device also eliminates the limitation of the conventional droplet-based microfluidic systems, namely clogging issues due to particle aggregation.

High-throughput screening program for botanical extracts

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
L Hingorani ◽  
NP Seeram ◽  
B Ebersole
Keyword(s):  
High Throughput ◽  
High Throughput Screening ◽  
Screening Program ◽  
Botanical Extracts

High throughput screening of microbial biodiversity for the discovery of novel cosmeceutical agents

Planta Medica ◽  
2015 ◽  
Vol 81 (16) ◽  
Author(s):  
K Georgousaki ◽  
N DePedro ◽  
AM Chinchilla ◽  
N Aliagiannis ◽  
F Vicente ◽  
...  
Keyword(s):  
High Throughput ◽  
High Throughput Screening ◽  
Microbial Biodiversity

High throughput screening to investigate Brazilian Cerrado biome plant extract bank chemical diversity

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
LS Espindola ◽  
RG Dusi ◽  
KR Gustafson ◽  
J McMahon ◽  
JA Beutler
Keyword(s):  
High Throughput ◽  
Plant Extract ◽  
High Throughput Screening ◽  
Chemical Diversity ◽  
Brazilian Cerrado ◽  
Cerrado Biome

High-throughput screening revealed a clinically relevant drug to induce sperm motility

2014 ◽  
Author(s):  
Clair Cochrane ◽  
Halil Ruso ◽  
Anthony Hope ◽  
Rosemary G Clarke ◽  
Christopher Barratt ◽  
...  
Keyword(s):  
Sperm Motility ◽  
High Throughput ◽  
High Throughput Screening
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