[18F]Fluoride PET Indicates Reduced Bone Formation in Severe Glucocorticoid-induced Osteoporosis

1998 ◽  
Vol 37 (02) ◽  
pp. 76-79 ◽  
Author(s):  
T. D. Kirchhoff ◽  
W. Burchert ◽  
J. v. d. Hoff ◽  
H. Zeidler ◽  
H. Hundeshagen ◽  
...  
Keyword(s):  
Bone Formation ◽  
Multiple Organ ◽  
High Dose ◽  
Multiple Fractures ◽  
Glucocorticoid Treatment ◽  
Organ Manifestations ◽  
Diagnostic Benefit ◽  
Sharp Syndrome ◽  
18F Fluoride

SummaryA 61-year-old female patient presenting with mixed connective tissue disease (Sharp syndrome), underwent a long-term high dose glucocorticoid treatment because of multiple organ manifestations. Under steroid therapy she developed severe osteoporosis resulting in multiple fractures. A dynamic [18F]fluoride PET study in this patient revealed reduced fluoride influx in non-fractured vertebrae. This finding corresponds to pathogenetic concepts which propose an inhibition of bone formation as major cause of glucocorticoid-induced osteoporosis. In the light of the presented case it seems to be promising to evaluate the diagnostic benefit of [18F]fluoride PET in osteoporosis.

scholarly journals SHARP Syndrome

2021 ◽  
Vol 9 (1) ◽  
pp. 61-63
Author(s):  
  Sanogo A ◽  
Diaby LM ◽  
B Berthe ◽  
Kane AST ◽  
Malle Mamadou ◽  
...  
Keyword(s):  
Sharp Syndrome

scholarly journals Toxic Epidermal Necrolysis after Pemetrexed and Cisplatin for Non-Small Cell Lung Cancer in a Patient with Sharp Syndrome

Onkologie ◽  
2012 ◽  
Vol 35 (12) ◽  
pp. 783-786 ◽  
Author(s):  
Cornelia Then ◽  
Jobst C. von Einem ◽  
Daniel Müller ◽  
Michael J. Flaig ◽  
Rudolf M. Huber ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Toxic Epidermal Necrolysis ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
Sharp Syndrome

Mixed connective tissue disease (Sharp syndrome): Description of two cases

1983 ◽  
Vol 4 (2) ◽  
pp. 203-205 ◽  
Author(s):  
A. Colombo ◽  
P. Bortolotti ◽  
M. Gibertoni ◽  
R. Schoenhuber ◽  
G. Gilioli ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Connective Tissue Disease ◽  
Mixed Connective Tissue Disease ◽  
Sharp Syndrome

scholarly journals Gastrointestinal tract involvement in mixed connective tissue disease (Sharp syndrome)

2020 ◽  
Vol 66 (6) ◽  
pp. e53-e57
Author(s):  
Lenka Nosáková ◽  
Martin Schnierer ◽  
Peter Bánovčin ◽  
Katarína Stašková ◽  
Martin Ďuríček ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Connective Tissue ◽  
Connective Tissue Disease ◽  
Mixed Connective Tissue Disease ◽  
Tract Involvement ◽  
Sharp Syndrome
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