Leksell Stereotactic Apparatus

Neurosurgery ◽  
1988 ◽  
Vol 22 (3) ◽  
pp. 454-464 ◽  
Author(s):  
Ken R. Winston ◽  
Wendell Lutz

Abstract A new system has been developed for stereotactically delivering prescribed high doses of radiation to precisely located volumes of approximately 0.6 to 10.0 ml within the brain. A Brown-Roberts-Wells stereotactic apparatus and a 6-MeV linear accelerator equipped with a special collimator (12.5 to 30 mm in diameter) have been adapted. The 20-mm collimator allows treatment of a nearly spherical volume of 2.1 ml. Outside the treatment field, the dosage declines to 80% of the dose prescribed for the periphery of the lesion over a distance of 1.8 mm and to 50% over the next 3.4 mm. Localization can be accomplished via computed tomography or cerebral angiography. Treatment is accomplished with an arcing beam of photon radiation with the turntable (couch) in each of four positions. The entire system has been extensively tested for accuracy in alignment and distribution of radiation. Errors have been measured for the alignment of the apparatus and for the process of localization. Safety of operation was emphasized throughout the design and testing phase. (Neurosurgery 22:454-464, 1988)


1997 ◽  
Vol 99 ◽  
pp. S162
Author(s):  
M. Taşkin ◽  
A. Dikilitaş ◽  
L. Uysal ◽  
K. Avlar ◽  
A. Aslan ◽  
...  

1984 ◽  
Vol 16 (5) ◽  
pp. 231-236 ◽  
Author(s):  
Lorette H. Mitchem

1982 ◽  
Vol 45 (6) ◽  
pp. 594-596
Author(s):  
Elson de A. Montagno ◽  
Blaine S. Nashold, Jr.

Author(s):  
Konrad Rydzynski

It was shown in vitro-on isolated mitochondria as well as on mitochondria from Ehrlich Ascites Tumor Cells-that adding of 2,4-dinitrophe- nol /DNP/ to the incubation medium leads to characteristic structural changes coinciding with adequate respiratory states. The aim of this study is to investigate, at the ultrastructural level, to what extent it would be possible to modify the configurational states in vivo on the model of the choroid plexus of rats' brain lateral ventricles. It produces the cerebrospinal fluid /CSP/, and is responsible for its composition through the active secretion of certain ions. ATP is indispensable in the process. It has been proved that DNP penetrates the plexus' epithelium and probably inhibits the active processes there by means of uncoupling the oxidative phosphorylation in the mitochondria.Material and MethodsWistar rats, weighed 280-330 g,were anesthetized with Nembutal /30 mg/kg i.p./ and fortal /1 mg/kg i.m./, then placed in stereotactic apparatus for ventriculo-cisternal perfusion.


1997 ◽  
Vol 99 ◽  
pp. S221
Author(s):  
S. Munemoto ◽  
M. Soma ◽  
Y. Hayashi

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