RLGS (restriction landmark genomic scanning)

2012 ◽  
Keyword(s):  
Restriction Landmark Genomic Scanning

Genomic alterations of human gliomas detected by restriction landmark genomic scanning

1997 ◽  
Vol 14 (1) ◽  
pp. 13-17 ◽  
Author(s):  
Mitsutoshi Nakamura ◽  
Noboru Konishi ◽  
Shigeru Tsunoda ◽  
Yoshio Hiasa ◽  
Kiyoshi Takemura ◽  
...  
Keyword(s):  
Human Gliomas ◽  
Restriction Landmark Genomic Scanning ◽  
Genomic Alterations

A single gel analysis of 575 dominant and codominant restriction landmark genomic scanning loci in mice interspecific backcross progeny

1995 ◽  
Vol 16 (1) ◽  
pp. 253-260 ◽  
Author(s):  
Hisato Okuizumi ◽  
Yasushi Okazaki ◽  
Tomoya Ohsumi ◽  
Takeshi Hanami ◽  
Yosuke Mizuno ◽  
...  
Keyword(s):  
Backcross Progeny ◽  
Interspecific Backcross ◽  
Restriction Landmark Genomic Scanning

Restriction landmark genomic scanning (RLGS) in fungi

Mycoscience ◽  
2001 ◽  
Vol 42 (3) ◽  
pp. 295-299 ◽  
Author(s):  
Keisuke Tomioka ◽  
Toyozo Sato
Keyword(s):  
Restriction Landmark Genomic Scanning

Genetic Variations in Human Benign Prostatic Hyperplasia Detected by Restriction Landmark Genomic Scanning

1997 ◽  
Vol 157 (4) ◽  
pp. 1499-1503 ◽  
Author(s):  
Noboru Konishi ◽  
Yoshio Hiasa ◽  
Hirofumi Matsuda ◽  
Mitsutoshi Nakamura ◽  
Yoshiteru Kitahori
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Genetic Variations ◽  
Prostatic Hyperplasia ◽  
Restriction Landmark Genomic Scanning

Genetic mapping of restriction landmark genomic scanning loci in the mouse

1995 ◽  
Vol 16 (1) ◽  
pp. 233-240 ◽  
Author(s):  
Hisato Okuizumi ◽  
Yasushi Okazaki ◽  
Tomoya Ohsumi ◽  
Yoshihide Hayashizaki ◽  
Christoph Plass ◽  
...  
Keyword(s):  
Genetic Mapping ◽  
Restriction Landmark Genomic Scanning

The use of restriction landmark genomic scanning to scan the mouse genome for endogenous loci with imprinted patterns of methylation

1995 ◽  
Vol 16 (1) ◽  
pp. 210-217 ◽  
Author(s):  
Hideo Shibata ◽  
Kiyoshi Yoshino ◽  
Masami Muramatsu ◽  
Christoph Plass ◽  
Verne M. Chapman ◽  
...  
Keyword(s):  
Mouse Genome ◽  
Restriction Landmark Genomic Scanning ◽  
Endogenous Loci

scholarly journals A genetic linkage map of the mouse using restriction landmark genomic scanning (RLGS).

Genetics ◽  
1994 ◽  
Vol 138 (4) ◽  
pp. 1207-1238 ◽  
Author(s):  
Y Hayashizaki ◽  
S Hirotsune ◽  
Y Okazaki ◽  
H Shibata ◽  
A Akasako ◽  
...  
Keyword(s):  
Genome Analysis ◽  
Genetic Linkage ◽  
Genetic Linkage Map ◽  
Mouse Genome ◽  
Restriction Enzymes ◽  
Genetic Maps ◽  
Mus Spretus ◽  
Restriction Landmark Genomic Scanning ◽  
Two Dimensional Gel Electrophoresis ◽  
Probe Hybridization

Abstract We have developed a multiplex method of genome analysis, restriction landmark genomic scanning (RLGS) that has been used to construct genetic maps in mice. Restriction landmarks are end-labeled restriction fragments of genomic DNA that are separated by using high resolution, two-dimensional gel electrophoresis identifying as many as two thousand landmark loci in a single gel. Variation for several hundred of these loci has been identified between laboratory strains and between these strains and Mus spretus. The segregation of more than 1100 RLGS loci has been analyzed in recombinant inbred (RI) strains and in two separate interspecific genetic crosses. Genetic maps have been derived that link 1045 RLGS loci to reference loci on all of the autosomes and the X chromosome of the mouse genome. The RLGS method can be applied to genome analysis in many different organisms to identify genomic loci because it uses end-labeling of restriction landmarks rather than probe hybridization. Different combinations of restriction enzymes yield different sets of RLGS loci providing expanded power for genetic mapping.

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