Intraoperative red blood cell salvage in posterior spinal fusions for idiopathic scoliosis: identifying potential criteria for selective use

2020 ◽  
Author(s):  
Garrett E. Wahl ◽  
Scott J. Luhmann
Keyword(s):  
Blood Cell ◽  
Idiopathic Scoliosis ◽  
Red Blood Cell ◽  
Cell Salvage ◽  
Spinal Fusions

scholarly journals Efficacy of Intraoperative Blood Salvage in Cerebral Aneurysm Surgery

2021 ◽  
Vol 10 (24) ◽  
pp. 5734
Author(s):  
Bedjan Behmanesh ◽  
Florian Gessler ◽  
Elisabeth Adam ◽  
Ulrich Strouhal ◽  
Sae-Yeon Won ◽  
...  
Keyword(s):  
Cost Effectiveness ◽  
Blood Cell ◽  
Cerebral Aneurysm ◽  
Red Blood Cell ◽  
Cerebral Aneurysms ◽  
Cell Salvage ◽  
Aneurysm Surgery ◽  
Allogenic Blood ◽  
Intraoperative Cell Salvage ◽  
Unruptured Cerebral Aneurysm

Background. The use and effectiveness of intraoperative cell salvage has been analyzed in many surgical specialties. Until now, no data exist evaluating the efficacy of intraoperative cell salvage in cerebral aneurysm surgery. Aim. To evaluate the efficacy and cost effectiveness of intraoperative cell salvage in cerebral aneurysm surgery. Methods. Data were collected retrospectively for all the patients who underwent cerebral aneurysm surgery at our institution between 2013 and 2019. Routinely, we apply blood salvage through autotransfusion. The cases were divided into a ruptured cerebral aneurysm group and a unruptured cerebral aneurysm group. Results. A total of 241 patients underwent cerebral aneurysm clipping. Of all the cerebral aneurysms, 116 were ruptured and 125 were unruptured and clipped electively. Age, location of the aneurysm, postoperative red blood cell count, intraoperative blood loss, and number of allogenic blood cell transfusions were statistically significantly different between the groups. The autotransfusion of salvaged blood could only be facilitated in eight cases with ruptured cerebral aneurysms and in none with unruptured cerebral aneurysms clipped electively (p < 0.01). Additionally, 35 patients with ruptured cerebral aneurysms and one patient with unruptured cerebral aneurysm required allogenic red blood cell transfusion after surgery, and 71 vs. 2 units of blood were transfused (p < 0.0001). In terms of cost effectiveness, a total of EUR 45,189 in 241 patients was spent to run the autotransfusion system, while EUR 13,797 was spent for allogenic blood transfusion. Conclusions. The use of cell salvage in patients with unruptured cerebral aneurysm, undergoing elective surgery, is not effective.

Perioperative Red Blood Cell Salvage in Spine Surgery

1992 ◽  
Vol 36 (6) ◽  
pp. 392
Author(s):  
M. J. BKHRMAN ◽  
H. A. KEIM
Keyword(s):  
Blood Cell ◽  
Spine Surgery ◽  
Red Blood Cell ◽  
Cell Salvage

scholarly journals Reduction of exposure to plasticizers in stored red blood cell units

Perfusion ◽  
2019 ◽  
Vol 35 (1) ◽  
pp. 32-38 ◽  
Author(s):  
Frank Münch ◽  
Thomas Göen ◽  
Robert Zimmermann ◽  
Werner Adler ◽  
Ariawan Purbojo ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Storage Time ◽  
Time Range ◽  
Cell Salvage ◽  
Chemical Contamination ◽  
Daily Lives ◽  
Duration Of Storage ◽  
Before And After ◽  
Ethylhexyl Phthalate

Introduction: Plastic can be toxic and hazardous to an organism’s health, but it is being widely used in our daily lives. Di-2-ethylhexyl-phthalate is the most common plasticizer in medical devices made of polyvinylchloride and is commonly found in soft bags storing red blood cell units. Di-2-ethylhexyl-phthalate and its degradation product mono-2-ethylhexyl-phthalate can migrate into human body fluids, for example, blood and tissues. The aim of the study was to assess the concentration of plasticizers in red blood cell units according to storage time and after mechanical rinsing using a cell salvage device. Methods: Levels of di-2-ethylhexyl-phthalate and mono-2-ethylhexyl-phthalate were analysed in 50 unwashed red blood cell units using liquid chromatography coupled with tandem mass spectrometry. In addition, phthalate concentrations were measured before and after mechanical rinsing in six more washed red blood cell units with storage times ranging between 36 and 56 days. A linear regression model was determined by the daily increase of di-2-ethylhexyl-phthalate and mono-2-ethylhexyl-phthalate in the stored red blood cell units subject to their storage time (range = 4-38 days), and the effect of mechanical rinsing on their phthalate concentration was calculated. Results: A linear correlation was found between storage time of unwashed red blood cell units and the concentration of di-2-ethylhexyl-phthalate (p < 0.001) or mono-2-ethylhexyl-phthalate (p < 0.001). Stored red blood cell units older than 14 days had significantly higher concentrations of both contaminants than red blood cell units of shorter storage time (p < 0.001). Mechanical rinsing in washed red blood cell units attained a reduction in the di-2-ethylhexyl-phthalate and mono-2-ethylhexyl-phthalate concentration by a median of 53% (range = 18-68%; p = 0.031) and 87% (range = 68-96%; p = 0.031), respectively. Conclusion: Leaching of di-2-ethylhexyl-phthalate and mono-2-ethylhexyl-phthalate into red blood cell units depends on the duration of storage time. Plasticizers can be significantly reduced by mechanical rinsing using cell salvage devices, and thus, red blood cell units can be regenerated with respect to chemical contamination.

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