Antimicrobial Susceptibility of 1,422 Haemophilus influenzae Isolates from Respiratory Tract Infections in Spain. Results of a 1-Year (1996-97) Multicenter Surveillance Study

Infection ◽  
1999 ◽  
Vol 27 (4-5) ◽  
pp. 265-267 ◽  
Author(s):  
J.A. García-Rodríguez ◽  
F. Baquero ◽  
J. García de Lomas ◽  
L. Aguilar
1999 ◽  
Vol 43 (2) ◽  
pp. 357-359 ◽  
Author(s):  
Fernando Baquero ◽  
José Angel García-Rodríguez ◽  
Juan García de Lomas ◽  
Lorenzo Aguilar ◽  

A nationwide susceptibility surveillance of 1,113Streptococcus pneumoniae isolates was carried out and found the following percentages of resistance: cefuroxime, 46%; penicillin, 37%; macrolides, 33%; aminopenicillins, 24%; cefotaxime, 13%; and ceftriaxone, 8%. A significant (P < 0.05) seasonality pattern for β-lactam antibiotics was observed. Resistance to macrolides was higher (P < 0.05) in middle-ear samples. Higher percentages of resistance to cefuroxime and macrolides were observed among penicillin-intermediate and -resistant strains, whereas high frequencies of resistance to aminopenicillins and expanded-spectrum cephalosporins were observed only among penicillin-resistant strains.


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