The AMPA Receptor Subunit GluA1 is Required for CA1 Hippocampal Long-Term Potentiation but is not Essential for Synaptic Transmission

2017 ◽  
Vol 44 (3) ◽  
pp. 549-561 ◽  
Author(s):  
Akira Terashima ◽  
Young Ho Suh ◽  
John T. R. Isaac
Keyword(s):  
Synaptic Transmission ◽  
Ampa Receptor ◽  
Long Term Potentiation ◽  
Receptor Subunit ◽  
Term Potentiation ◽  
Ampa Receptor Subunit

scholarly journals Long-term potentiation is independent of the C-tail of the GluA1 AMPA receptor subunit

eLife ◽  
2020 ◽  
Vol 9 ◽  
Author(s):  
Javier Díaz-Alonso ◽  
Wade Morishita ◽  
Salvatore Incontro ◽  
Jeffrey Simms ◽  
Julia Holtzman ◽  
...  
Keyword(s):  
Spatial Memory ◽  
Morris Water Maze ◽  
Ampa Receptor ◽  
Water Maze ◽  
Long Term Potentiation ◽  
Receptor Subunit ◽  
Terminal Domain ◽  
Term Potentiation ◽  
Ampa Receptor Subunit

We tested the proposal that the C-terminal domain (CTD) of the AMPAR subunit GluA1 is required for LTP. We found that a knock-in mouse lacking the CTD of GluA1 expresses normal LTP and spatial memory, assayed by the Morris water maze. Our results support a model in which LTP generates synaptic slots, which capture passively diffusing AMPARs.

scholarly journals A Juvenile form of Postsynaptic Hippocampal Long‐Term Potentiation in Mice Deficient for the AMPA Receptor Subunit GluR‐A

2003 ◽  
Vol 553 (3) ◽  
pp. 843-856 ◽  
Author(s):  
Vidar Jensen ◽  
Katharina M. M. Kaiser ◽  
Thilo Borchardt ◽  
Giselind Adelmann ◽  
Andrei Rozov ◽  
...  
Keyword(s):  
Ampa Receptor ◽  
Long Term Potentiation ◽  
Receptor Subunit ◽  
Juvenile Form ◽  
Term Potentiation ◽  
Ampa Receptor Subunit

scholarly journals Author response: Long-term potentiation is independent of the C-tail of the GluA1 AMPA receptor subunit

2020 ◽  
Author(s):  
Javier Díaz-Alonso ◽  
Wade Morishita ◽  
Salvatore Incontro ◽  
Jeffrey Simms ◽  
Julia Holtzman ◽  
...  
Keyword(s):  
Ampa Receptor ◽  
Long Term Potentiation ◽  
Author Response ◽  
Receptor Subunit ◽  
Term Potentiation ◽  
Ampa Receptor Subunit

Orphanin FQ inhibits synaptic transmission and long-term potentiation in rat hippocampus

Hippocampus ◽  
1997 ◽  
Vol 7 (1) ◽  
pp. 88-94 ◽  
Author(s):  
Tzu-Ping Yu ◽  
Jeffrey Fein ◽  
Tien Phan ◽  
Christopher J. Evans ◽  
Cui-Wei Xie
Keyword(s):  
Synaptic Transmission ◽  
Long Term Potentiation ◽  
Rat Hippocampus ◽  
Orphanin Fq ◽  
Term Potentiation
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