Acidic extracellular pH shifts colorectal cancer cell death from apoptosis to necrosis upon exposure to propionate and acetate, major end-products of the human probiotic propionibacteria

APOPTOSIS ◽  
2006 ◽  
Vol 12 (3) ◽  
pp. 573-591 ◽  
Author(s):  
Annaïg Lan ◽  
Dominique Lagadic-Gossmann ◽  
Christophe Lemaire ◽  
Catherine Brenner ◽  
Gwénaël Jan
Keyword(s):  
Colorectal Cancer ◽  
Cell Death ◽  
Cancer Cell ◽  
Extracellular Ph ◽  
Colorectal Cancer Cell ◽  
Cancer Cell Death ◽  
End Products ◽  
Acidic Extracellular Ph

scholarly journals The CDK4/6 inhibitor palbociclib synergizes with irinotecan to promote colorectal cancer cell death under hypoxia

Cell Cycle ◽  
2017 ◽  
Vol 16 (12) ◽  
pp. 1193-1200 ◽  
Author(s):  
Jun Zhang ◽  
Lanlan Zhou ◽  
Shuai Zhao ◽  
David T. Dicker ◽  
Wafik S. El-Deiry
Keyword(s):  
Colorectal Cancer ◽  
Cell Death ◽  
Cancer Cell ◽  
Colorectal Cancer Cell ◽  
Cancer Cell Death

scholarly journals c-FLIP: A Key Regulator of Colorectal Cancer Cell Death

2007 ◽  
Vol 67 (12) ◽  
pp. 5754-5762 ◽  
Author(s):  
Timothy R. Wilson ◽  
Kirsty M. McLaughlin ◽  
Miranda McEwan ◽  
Hidekazu Sakai ◽  
Katherine M.A. Rogers ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cell Death ◽  
Cancer Cell ◽  
Colorectal Cancer Cell ◽  
Cancer Cell Death

The small molecule AU14022 promotes colorectal cancer cell death via p53-mediated G2/M-phase arrest and mitochondria-mediated apoptosis

2018 ◽  
Vol 233 (6) ◽  
pp. 4666-4676 ◽  
Author(s):  
Hwani Ryu ◽  
Ky-Youb Nam ◽  
Jae Sung Kim ◽  
Sang-Gu Hwang ◽  
Jie-Young Song ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cell Death ◽  
Cancer Cell ◽  
Small Molecule ◽  
Colorectal Cancer Cell ◽  
Cancer Cell Death ◽  
Phase Arrest ◽  
M Phase

scholarly journals The effects of a novel aliphatic-chain hydroxamate derivative WMJ-S-001 in HCT116 colorectal cancer cell death

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Yu-Han Huang ◽  
Shiu-Wen Huang ◽  
Ya-Fen Hsu ◽  
George Ou ◽  
Wei-Jan Huang ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cell Death ◽  
Cancer Cell ◽  
Colorectal Cancer Cell ◽  
Aliphatic Chain ◽  
Cancer Cell Death

M1190 5-Aminosalicylic Acid Induces Colorectal Cancer Cell Death In Vitro and In Vivo

2010 ◽  
Vol 138 (5) ◽  
pp. S-351
Author(s):  
Pim J. Koelink ◽  
Alexandra Langers ◽  
Wouter H. De Vos tot Nederveen Cappel ◽  
Cornelis B. Lamers ◽  
Daniel W. Hommes ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cell Death ◽  
Cancer Cell ◽  
Colorectal Cancer Cell ◽  
Aminosalicylic Acid ◽  
Cancer Cell Death

5-Aminosalicylic acid enhances anchorage-independent colorectal cancer cell death

2006 ◽  
Vol 42 (15) ◽  
pp. 2609-2616 ◽  
Author(s):  
Daniele Fina ◽  
Luigi Franchi ◽  
Roberta Caruso ◽  
Ilaria Peluso ◽  
Gian Carlo Naccari ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cell Death ◽  
Cancer Cell ◽  
Colorectal Cancer Cell ◽  
Aminosalicylic Acid ◽  
Cancer Cell Death

scholarly journals c-FLIP inhibits chemotherapy-induced colorectal cancer cell death

Oncogene ◽  
2005 ◽  
Vol 25 (6) ◽  
pp. 838-848 ◽  
Author(s):  
D B Longley ◽  
T R Wilson ◽  
M McEwan ◽  
W L Allen ◽  
U McDermott ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cell Death ◽  
Cancer Cell ◽  
Colorectal Cancer Cell ◽  
Cancer Cell Death

scholarly journals Bone marrow-derived mesenchymal stromal cells promote colorectal cancer cell death under low-dose irradiation

2018 ◽  
Vol 118 (3) ◽  
pp. 353-365 ◽  
Author(s):  
Hao Feng ◽  
Jing-kun Zhao ◽  
Tobias S Schiergens ◽  
Pu-xiongzhi Wang ◽  
Bao-chi Ou ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Bone Marrow ◽  
Cell Death ◽  
Cancer Cell ◽  
Mesenchymal Stromal Cells ◽  
Stromal Cells ◽  
Low Dose ◽  
Colorectal Cancer Cell ◽  
Cancer Cell Death ◽  
Dose Irradiation
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