The Ljubljana classification of epithelial hyperplastic laryngeal lesions: a morphometric evaluation of nuclear pleomorphism

Pathologica ◽  
2002 ◽  
Vol 94 (6) ◽  
pp. 290-298 ◽  
Author(s):  
T. Valente ◽  
T. Lettini ◽  
R. Ricco ◽  
L. Resta ◽  
G. Serio ◽  
...  
2020 ◽  
Vol 6 (3) ◽  
pp. 70-73
Author(s):  
Nazila Esmaeili ◽  
Alfredo Illanes ◽  
Axel Boese ◽  
Nikolaos Davaris ◽  
Christoph Arens ◽  
...  

AbstractLongitudinal and perpendicular changes in the blood vessels of the vocal fold have been related to the advancement from benign to malignant laryngeal cancer stages. The combination of Contact Endoscopy (CE) and Narrow Band Imaging (NBI) provides intraoperative realtime visualization of vascular pattern in Larynx. The evaluation of these vascular patterns in CE+NBI images is a subjective process leading to differentiation difficulty and subjectivity between benign and malignant lesions. The main objective of this work is to compare multi-observer classification versus automatic classification of laryngeal lesions. Six clinicians visually classified CE+NBI images into benign and malignant lesions. For the automatic classification of CE+NBI images, we used an algorithm based on characterizing the level of the vessel’s disorder. The results of the manual classification showed that there is no objective interpretation, leading to difficulties to visually distinguish between benign and malignant lesions. The results of the automatic classification of CE+NBI images on the other hand showed the capability of the algorithm to solve these issues. Based on the observed results we believe that, the automatic approach could be a valuable tool to assist clinicians to classifying laryngeal lesions.


2000 ◽  
Vol 25 (3) ◽  
pp. 227-232 ◽  
Author(s):  
N. Gale ◽  
N. Zidar ◽  
J. Fischinger ◽  
V. Kambic

Author(s):  
Godson Emeka Anyanwu ◽  
Salome Nwaelom Ezeofor ◽  
Emmanuel Nebuwa Obikili ◽  
Ekene Valentine Ugbor

Background: Radiological identification is important in clinical, surgical and forensic medicine particularly in the absence of comparative deoxyribonucleic Acid (DNA) samples and fingerprints. Aim is to establish the morphometry of frontal sinus (FS), maxillary sinus (MS) and bizygomatic distance (BZD) and their relationship with age and gender in Igbos and Ogonis of Nigeria using computed tomography (CT). Methods: Head CT scans of 625 subjects (477 Igbos and 148 Ogonis) between 18 and 85 years, showing normal FS, MS and BZD, were measured using DICOM viewer software. The Igbos and Ogonis were 247 males and 230 females; 84 males and 64 females respectively. The height, width and depth of the sinuses, intermaxillary sinus distances (IMD) and BZD were measured in centimeters (cm). The data were analyzed using SPSS version 20 and difference between groups was obtained using one way ANOVA. P-value less than 0.05 was considered as statistically significant. Results: Mean values for the right and left MS volume for the Igbos are 13.79 ±10.91 and 13.81±11.03 and for the Ogonis 20.84±5.83 and 20.19±5.59 cm respectively. All FS dimensions are higher in the Igbos (P<0.001) except right FS depth. Mean IMD are 3.64±0.50 and 3.39±0.45 cm in the Igbos and Ogonis respectively (P<0.001). Ogonis have higher BZD (P>0.05). In both groups, males had larger values in both FS depth, MS dimensions and BZD (P<0.001). Age correlated positively with left FS height and IMD. Prevalence of unilateral FS aplasia was 3.35% on the right and 1.47% on the left among the Igbos while the Ogonis have 2.03% on the right and 2.70% on the left. Bilateral FS aplasia was 2.94% among the Igbos but not observed among the Ogonis. Conclusion: Normative values is established. Ethnic differences exists with Igbos significantly having higher values of FS and IMD while in the Ogonis, the MS dimensions are higher. These findings would act as a guide for facial reconstructive surgeries, forensic experts and classification of fossil remains in anthropology.


2012 ◽  
Vol 126 (10) ◽  
pp. 1041-1044 ◽  
Author(s):  
A Mahmoud ◽  
I D Miziara ◽  
K C Costa ◽  
C G Santi ◽  
C W Maruta ◽  
...  

AbstractObjective:(1) To investigate the incidence of laryngeal involvement in a large series of patients with pemphigus vulgaris, using endoscopic examination, (2) to describe the lesions, and (3) to establish a classification of laryngeal involvement in pemphigus vulgaris based on the location of the lesions.Study design:Prospective study.Methods:A total of 40 sequentially treated pemphigus vulgaris patients, diagnosed using clinical, histological and immunofluorescence criteria, were evaluated for laryngeal manifestations using endoscopic examination. The results were used to establish a graded classification of laryngeal involvement according to the location of the lesions.Results:Active laryngeal lesions (ulcers or blisters) were found in 16 patients (40 per cent). Of these, 37.5 per cent were classified as grade I, 20 per cent as grade II, 20 per cent as grade III and 17.5 per cent as grade IV.Conclusion:Laryngeal involvement is common in pemphigus vulgaris and must be considered at the point of diagnosis. Grade I lesions are the most frequent.


1999 ◽  
Vol 35 (6) ◽  
pp. 579-579
Author(s):  
Friedman ◽  
Shah ◽  
Salto-Tellez
Keyword(s):  

2020 ◽  
Vol 1 (1) ◽  
pp. 29
Author(s):  
Hadiyyatan Waasilah ◽  
Riries Rulaningtyas ◽  
Winarno Winarno ◽  
Anny Setijo Rahaju

Histopathological assessment is one of the examinations that allows the classification of breast cancer based on its level. Histopathological assessment factors are based on tubule formation, nuclear pleomorphism, and the mitotic count. This study only focused on tubule formation. The tubule formation was represented by a lumen surrounded a  nucleus. The segmentation of tubule histopathology of breast cancer method was using a combination of k-means clustering and graph cut. The image data used in this study were 15 images of breast cancer histopathology preparations using 5 variations in the number of clusters (k) in the k-means clustering method. The best results of tubule formation segmentation using k = 4, with an average value of balanced accuracy was 81.08% and the most optimal balanced accuracy results was 94.34%.


1966 ◽  
Vol 24 ◽  
pp. 21-23
Author(s):  
Y. Fujita

We have investigated the spectrograms (dispersion: 8Å/mm) in the photographic infrared region fromλ7500 toλ9000 of some carbon stars obtained by the coudé spectrograph of the 74-inch reflector attached to the Okayama Astrophysical Observatory. The names of the stars investigated are listed in Table 1.


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