Study of phagocytosis of senescent erythrocytes in young and elderly individuals

We developed two distinct forest therapy programs (FTPs) and compared their effects on dementia prevention and related health problems for older adults. One was focused on Qigong practice in the forest (QP) and the other involved active walking in the forest (WP). Both FTPs consisted of twelve 2-h sessions over six weeks and were conducted in an urban forest. We obtained data from 25, 18, and 26 participants aged 65 years or above for the QP, WP, and control groups, respectively. Neuropsychological scores via cognition (MoCA), geriatric depression (GDS) and quality of life (EQ-5D), and electrophysiological variables (electroencephalography, bioimpedance, and heart rate variability) were measured. We analyzed the intervention effects with a generalized linear model. Compared to the control group, the WP group showed benefits in terms of neurocognition (increases in the MoCA score, and alpha and beta band power values in the electroencephalogram), sympathetic nervous activity, and bioimpedance in the lower body. On the other hand, the QP group showed alleviated depression and an increased bioimpedance phase angle in the upper body. In conclusion, both active walking and Qigong in the forest were shown to have distinctive neuropsychological and electrophysiological benefits, and both had beneficial effects in terms of preventing dementia and relieving related health problems for elderly individuals.

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Relationship between fall behavior and quality of life of elderly individuals

Psychology Health & Medicine ◽

10.1080/13548506.2021.1883686 ◽

2021 ◽

pp. 1-8

Author(s):

Hanife Durgun ◽

Nuray Turan ◽

Hatice Kaya

Keyword(s):

Quality Of Life ◽

Elderly Individuals

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Effect of aquatic exercise on mental health, functional autonomy, and oxidative damages in diabetes elderly individuals

International Journal of Environmental Health Research ◽

10.1080/09603123.2021.1943324 ◽

2021 ◽

pp. 1-14

Author(s):

Luciano Acordi da Silva ◽

Lorhan da Silva Menguer ◽

Ramiro Doyenart ◽

Daniel Boeira ◽

Yuri Pinheiro Milhomens ◽

...

Keyword(s):

Mental Health ◽

Aquatic Exercise ◽

Elderly Individuals ◽

Oxidative Damages ◽

Functional Autonomy

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Relationship between Psychological Distress and Prolonged Sedentary Bouts in the Elderly: Four Period Analysis

Healthcare ◽

10.3390/healthcare9060676 ◽

2021 ◽

Vol 9 (6) ◽

pp. 676

Author(s):

Yutaka Owari

Keyword(s):

Mental Health ◽

Psychological Distress ◽

Structural Equation ◽

Goodness Of Fit ◽

Secondary Analysis ◽

The Elderly ◽

Sample Population ◽

Elderly Individuals ◽

Sedentary Bouts ◽

Fit Index

Background: Too much sitting is associated with low mental health in elderly individuals. We clarified the relationship between psychological distress and the rate of prolonged sedentary bouts (PSBs) among the elderly over four periods. Methods: In a secondary analysis, a sample population of 68 adults aged 65 years or older in Japan was used. The following proxy variables were used: PSB (mental health) and the Kessler 6 scale; K6 scores (psychological distress). Results: Using the cross-lagged effects models, from “2016 K6” to “2017 PSB” (p = 0.004), from “2017 K6” to “2018 PSB” (p < 0.001), and from “2018 K6” to “2019 PSB” (p = 0.021) were all significant; however, the reverse were not all significant in one period. In four periods, from “2016 PSB” to “2019 K6” (p = 0.025) was significant; however, the reverse was not significant. Fit indices were obtained: χ2 = 7.641 (p = 0.182), goodness of fit index (GFI) = 0.891, comparative fit index (CFI) = 0.901, and root mean square error of approximation (RMSEA) = 0.121 in structural equation modelling. Conclusions: Psychological distress may affect the rate of PSB after one year, and the rate of PSB may affect the rate of psychological distress after three years in elderly individuals.

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Analysis of in vitro digestion using human gut microbiota in adult and elderly individuals

Food Chemistry ◽

10.1016/j.foodchem.2021.130228 ◽

2021 ◽

pp. 130228

Author(s):

Seung Yun Lee ◽

Da Young Lee ◽

Hea Jin Kang ◽

Ji Hyeop Kang ◽

Hae Won Jang ◽

...

Keyword(s):

Gut Microbiota ◽

In Vitro Digestion ◽

Human Gut ◽

Elderly Individuals ◽

Human Gut Microbiota

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Impaired Cerebrovascular Hemodynamics are Associated with Cerebral White Matter Damage

Journal of Cerebral Blood Flow & Metabolism ◽

10.1038/jcbfm.2013.180 ◽

2013 ◽

Vol 34 (2) ◽

pp. 228-234 ◽

Cited By ~ 70

Author(s):

Sushmita Purkayastha ◽

Otite Fadar ◽

Aujan Mehregan ◽

David H Salat ◽

Nicola Moscufo ◽

...

Keyword(s):

White Matter ◽

Middle Cerebral Artery ◽

Cerebral Artery ◽

Cerebral Autoregulation ◽

Structural Integrity ◽

Cerebral White Matter ◽

Elderly Individuals ◽

Transfer Function Analysis ◽

Dynamic Cerebral Autoregulation ◽

Cerebrovascular Hemodynamics

White matter hyperintensities (WMH) in elderly individuals with vascular diseases are presumed to be due to ischemic small vessel diseases; however, their etiology is unknown. We examined the cross-sectional relationship between cerebrovascular hemodynamics and white matter structural integrity in elderly individuals with vascular risk factors. White matter hyperintensity volumes, fractional anisotropy (FA), and mean diffusivity (MD) were obtained from MRI in 48 subjects (75±7years). Pulsatility index (PI) and dynamic cerebral autoregulation (dCA) was assessed using transcranial Doppler ultrasound of the middle cerebral artery. Dynamic cerebral autoregulation was calculated from transfer function analysis (phase and gain) of spontaneous blood pressure and flow velocity oscillations in the low (LF, 0.03 to 0.15 Hz) and high (HF, 0.16 to 0.5 Hz) frequency ranges. Higher PI was associated with greater WMH ( P<0.005). Higher phase across all frequency ranges was associated with greater FA and lower MD ( P<0.005). Lower gain was associated with higher FA in the LF range ( P=0.001). These relationships between phase and FA were significant in the territories limited to the middle cerebral artery as well as across the entire brain. Our results show a strong relationship between impaired cerebrovascular hemodynamics (PI and dCA) and loss of cerebral white matter structural integrity (WMH and DTI metrics) in elderly individuals.

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