Effects of adjuvant radiotherapy on bowel function and anorectal physiology after low anterior resection for rectal cancer

2000 ◽  
Vol 4 (1) ◽  
pp. 13-16 ◽  
Author(s):  
Y.H. Ho ◽  
K.S. Lee ◽  
K.W. Eu ◽  
F. Seow-Choen
Keyword(s):  
Rectal Cancer ◽  
Anterior Resection ◽  
Adjuvant Radiotherapy ◽  
Low Anterior Resection ◽  
Bowel Function ◽  
Anorectal Physiology

T1712 Postoperative Bowel Function After Lumber Colonic Nerve Preserving Low Anterior Resection for Rectal Cancer

2008 ◽  
Vol 134 (4) ◽  
pp. A-882-A-883
Author(s):  
Yoshitaka Tanabe ◽  
Hiroaki Matsunaga ◽  
Takashi Ueki ◽  
Shosaku Nakahara ◽  
Masao Tanaka
Keyword(s):  
Rectal Cancer ◽  
Anterior Resection ◽  
Low Anterior Resection ◽  
Bowel Function

scholarly journals Impact of a defunctioning ileostomy and time to stoma closure on bowel function after low anterior resection for rectal cancer: a systematic review and meta-analysis

2021 ◽  
Author(s):  
I. Vogel ◽  
N. Reeves ◽  
P. J. Tanis ◽  
W. A. Bemelman ◽  
J. Torkington ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Rectal Cancer ◽  
Anterior Resection ◽  
Low Anterior Resection ◽  
Bowel Function ◽  
Ileostomy Closure ◽  
Stoma Closure ◽  
Defunctioning Ileostomy

Abstract Background Impaired bowel function after low anterior resection (LAR) for rectal cancer is a frequent problem with a major impact on quality of life. The aim of this study was to assess the impact of a defunctioning ileostomy, and time to ileostomy closure on bowel function after LAR for rectal cancer. Methods We performed a systematic review based on the preferred reporting items for systematic reviews and meta-analyses (PRISMA) statement. Comprehensive literature searches were conducted using PubMed, Embase and Cochrane databases for articles published from 1989 up to August 2019. Analysis was performed using Review Manager (version 5.3) using a random-effects model. Results The search yielded 11 studies (1400 patients) that reported on functional outcome after LAR with at least 1 year follow-up, except for one study. Five scales were used: the Low Anterior Resection Syndrome (LARS) score, the Wexner score, the Memorial Sloan Kettering Cancer Centre Bowel Function Instrument, the Fecal Incontinence Quality of Life scale, and the Hallbook questionnaire. Based on seven studies, major LARS occurred more often in the ileostomy group (OR 2.84, 95% CI, 1.70–4.75, p < 0.0001: I2 = 60%, X2 = 0.02). Based on six studies, a longer time to stoma closure increased the risk of major LARS with a mean difference in time to closure of 2.39 months (95% CI, 1.28–3.51, p < 0.0001: I2 = 21%, X2 = 0.28) in the major vs. no LARS group. Other scoring systems could not be pooled, but presence of an ileostomy predicted poorer bowel function except with the Hallbook questionnaire. Conclusions The risk of developing major LARS seems higher with a defunctioning ileostomy. A prolonged time to ileostomy closure seems to reinforce the negative effect on bowel function; therefore, early reversal should be an important part of the patient pathway.

scholarly journals Translation, validation and psychometric evaluation of the Persian (Farsi) version of the Low Anterior Resection Syndrome Score (LARS-P)

PLoS ONE ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. e0247054
Author(s):  
Mohammad Reza Keramati ◽  
Ali Abbaszadeh-Kasbi ◽  
Amir Keshvari ◽  
Seyed Mohsen Ahmadi-Tafti ◽  
Behnam Behboudi ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Psychometric Properties ◽  
Anterior Resection ◽  
Low Anterior Resection ◽  
Convergent Validity ◽  
High Reliability ◽  
Bowel Function ◽  
Lars Score ◽  
Patient Reported ◽  
The Impact

Introduction Low anterior resection (LAR) for rectal cancer affects bowel function after the operation, causing a group of symptoms known as LAR Syndrome (LARS). LARS score is a patient-reported questionnaire to assess bowel dysfunction after the LAR operation. This study performed to validate the Persian (Farsi) translation of the LARS score and to investigate the psychometric properties of the score. The impact of LARS on the Quality of Life (QoL) of patients was also assessed. Materials and methods The LARS score was translated into Persian. Participants with a history of rectal cancer and low anterior resection were asked to complete the LARS score questionnaire. They were also asked a single question evaluating the impact of bowel function on QoL. Discriminative validity, convergent validity, sensitivity, and specificity of the questionnaire were calculated. A group of patients completed the score twice to assess the reliability of the questionnaire. Results From 358 patients with rectal cancer, 101 participants completed the Persian questionnaire. Answers of a high fraction of participants showed a moderate/perfect fit between their LARS score and their QoL. The Persian score demonstrated good convergent validity. It was able to differentiate between participants in terms of gender and T staging of the primary tumor. The score had high reliability. Conclusion The Persian translation of the LARS score has excellent psychometric properties compared to previous translations in other languages. Therefore, it is a valid and reliable questionnaire to assess LARS.

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