"In situ preparation": new surgical procedure indicated for soft-tissue sarcoma of a lower limb in close proximity to major neurovascular structures

2002 ◽  
Vol 7 (1) ◽  
pp. 51-56 ◽  
Author(s):  
S. Matsumoto ◽  
N. Kawaguchi ◽  
J. Manabe ◽  
Y. Matsushita
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Lower Limb ◽  
Surgical Procedure ◽  
In Situ Preparation ◽  
Close Proximity ◽  
Neurovascular Structures

scholarly journals Treatment of a Malignant Soft Tissue Tumor Arising in the Vicinity of the Sciatic Nerve with an In-Situ Preparation Technique and Intensive Multidisciplinary Therapy

Cancers ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 506 ◽  
Author(s):  
Hisaki Aiba ◽  
Katsuhiro Hayashi ◽  
Satoshi Yamada ◽  
Hideki Okamoto ◽  
Hiroaki Kimura ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Sciatic Nerve ◽  
Wide Resection ◽  
Preparation Technique ◽  
Musculoskeletal Tumor ◽  
Musculoskeletal Tumor Society ◽  
In Situ Preparation ◽  
First Case ◽  
Malignant Soft Tissue Tumor

Preservation of the sciatic nerve is difficult in cases of highly malignant soft tissuetumors closely surrounding the nerve. Herein, we present the first case of preservation of thisnerve by combining an in-situ preparation technique (ISP; a technique enabling the preparation ofneurovascular bundles without contamination by tumor cells) with intensive concurrent neoadjuvantchemo-radiotherapy with hyperthermia (RHC; radio-hyperthermo-chemotherapy). A 62-year-oldman presented with a soft tissue mass in the right thigh and was diagnosed with undifferentiatedpleomorphic sarcoma. The tumor arose in the multi-compartment areas of the posterior thigh musclesand was closely intertwined with the sciatic nerve. As preoperative therapy, RHC was performedfor surgical down-staging and the tumor partially responded. Afterwards, wide resection of thetumor with preservation of the sciatic nerve using ISP was performed. Following the surgery, therehas not been recurrence in the affected site and the functional outcomes of the lower extremityachieved 80% in the Musculoskeletal Tumor Society score. The patient is still alive with disease fiveyears postoperatively. This is the first case in which ISP and RHC procedures were combined forthe preservation of the neurovascular structure. Further study is needed for the validation of thefeasibility of this method.

The influence of different patient positions on the preoperative 3D planning for surgical resection of soft tissue sarcoma in the lower limb-a cadaver pilot study

2020 ◽  
Vol 35 ◽  
pp. 478-483
Author(s):  
Dominik Kaiser ◽  
Armando Hoch ◽  
Philipp Kriechling ◽  
Dimitri N. Graf ◽  
Felix W.A. Waibel ◽  
...  
Keyword(s):  
Pilot Study ◽  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Surgical Resection ◽  
Lower Limb

Analysis of immediate vascular reconstruction for lower-limb salvage in patients with lower-limb bone and soft-tissue sarcoma

2013 ◽  
Vol 66 (5) ◽  
pp. 608-616 ◽  
Author(s):  
Hiroki Umezawa ◽  
Minoru Sakuraba ◽  
Shinpei Miyamoto ◽  
Shougo Nagamatsu ◽  
Shuji Kayano ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Limb Salvage ◽  
Lower Limb ◽  
Vascular Reconstruction ◽  
Limb Bone

The Indications for and the Prognostic Significance of Amputation as the Primary Surgical Procedure for Localized Soft Tissue Sarcoma of the Extremity

2004 ◽  
Vol 12 (1) ◽  
pp. 10-17 ◽  
Author(s):  
Michelle A. Ghert ◽  
Adesegun Abudu ◽  
Natasha Driver ◽  
Aileen M. Davis ◽  
Anthony M. Griffin ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Surgical Procedure ◽  
Prognostic Significance

scholarly journals Management of Lower Limb Soft Tissue Sarcomas with Major Neurovascular Involvement: Current and Future Perspectives

EMJ Oncology ◽  
2021 ◽  
pp. 91-99
Author(s):  
Noor Tamimi ◽  
Hussein Sweiti
Keyword(s):  
Soft Tissue ◽  
Lower Limb ◽  
Functional Outcomes ◽  
Multidisciplinary Approach ◽  
Treatment Algorithm ◽  
Soft Tissue Sarcomas ◽  
Classification Systems ◽  
Appropriate Treatment ◽  
Neurovascular Structures ◽  
Mesenchymal Tumours

Lower limb soft tissue sarcomas are a group of rare mesenchymal tumours that may grow in close anatomical proximity to major neurovascular structures, leading to significant oncological and surgical challenges for treating physicians. This article reviews the current literature on the multidisciplinary approach of treating lower limb soft tissue sarcomas with neurovascular involvement and describes the increasing shift towards limb-sparing surgeries, with an emphasis on improved functional outcomes based on a multimodal treatment approach. In addition to identifying the histological subtype of the tumour, classifying the neurovascular involvement precisely is key in planning the appropriate treatment. Existing classification systems for both vascular and neural involvement are discussed, and a combined neurovascular classification is proposed together with a general treatment algorithm.

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