Role of dopamine D 1 receptors in the control of striatal acetylcholine release by endogenous dopamine

2001 ◽  
Vol 22 (1) ◽  
pp. 41-42 ◽  
Author(s):  
E. Acquas ◽  
G. Di Chiara
2012 ◽  
Vol 89 (5-6) ◽  
pp. 177-184 ◽  
Author(s):  
Polina Petkova-Kirova ◽  
Maria Grazia Giovannini ◽  
Reni Kalfin ◽  
Angelina Rakovska

Neuroscience ◽  
1999 ◽  
Vol 88 (3) ◽  
pp. 811-822 ◽  
Author(s):  
H Moore ◽  
J Fadel ◽  
M Sarter ◽  
J.P Bruno

Author(s):  
Stuart M. Tomares ◽  
Owen S. Bamford ◽  
Laura M. Sterni ◽  
Robert S. Fitzgerald ◽  
John L. Carroll

2002 ◽  
Vol 12 ◽  
pp. 374-375
Author(s):  
E. Elvander ◽  
P.A. Schött ◽  
J. Kehr ◽  
P. Mannström ◽  
B. Bjelke ◽  
...  

2006 ◽  
Vol 291 (5) ◽  
pp. H2187-H2191 ◽  
Author(s):  
Toru Kawada ◽  
Toji Yamazaki ◽  
Tsuyoshi Akiyama ◽  
Kazunori Uemura ◽  
Atsunori Kamiya ◽  
...  

Although an axoplasmic Ca2+ increase is associated with an exocytotic acetylcholine (ACh) release from the parasympathetic postganglionic nerve endings, the role of voltage-dependent Ca2+ channels in ACh release in the mammalian cardiac parasympathetic nerve is not clearly understood. Using a cardiac microdialysis technique, we examined the effects of Ca2+ channel antagonists on vagal nerve stimulation- and ischemia-induced myocardial interstitial ACh releases in anesthetized cats. The vagal stimulation-induced ACh release [22.4 nM (SD 10.6), n = 7] was significantly attenuated by local administration of an N-type Ca2+ channel antagonist ω-conotoxin GVIA [11.7 nM (SD 5.8), n = 7, P = 0.0054], or a P/Q-type Ca2+ channel antagonist ω-conotoxin MVIIC [3.8 nM (SD 2.3), n = 6, P = 0.0002] but not by local administration of an L-type Ca2+ channel antagonist verapamil [23.5 nM (SD 6.0), n = 5, P = 0.758]. The ischemia-induced myocardial interstitial ACh release [15.0 nM (SD 8.3), n = 8] was not attenuated by local administration of the L-, N-, or P/Q-type Ca2+ channel antagonists, by inhibition of Na+/Ca2+ exchange, or by blockade of inositol 1,4,5-trisphosphate [Ins( 1 , 4 , 5 )P3] receptor but was significantly suppressed by local administration of gadolinium [2.8 nM (SD 2.6), n = 6, P = 0.0283]. In conclusion, stimulation-induced ACh release from the cardiac postganglionic nerves depends on the N- and P/Q-type Ca2+ channels (with a dominance of P/Q-type) but probably not on the L-type Ca2+ channels in cats. In contrast, ischemia-induced ACh release depends on nonselective cation channels or cation-selective stretch activated channels but not on L-, N-, or P/Q type Ca2+ channels, Na+/Ca2+ exchange, or Ins( 1 , 4 , 5 )P3 receptor-mediated pathway.


2007 ◽  
Vol 559 (2-3) ◽  
pp. 155-160 ◽  
Author(s):  
Maiko Sato ◽  
Yukio Ago ◽  
Ken Koda ◽  
Shigeo Nakamura ◽  
Toshiyuki Kawasaki ◽  
...  

1992 ◽  
Vol 59 (4) ◽  
pp. 1555-1557 ◽  
Author(s):  
Silvana Consolo ◽  
Prisca Girotti ◽  
Giovanni Russi ◽  
Gaetano Di Chiara

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