Recurrence of ibuprofen-induced aseptic meningitis in an otherwise healthy patient

1999 ◽  
Vol 20 (1) ◽  
pp. 59-62 ◽  
Author(s):  
E. Pisani ◽  
C. Fattorello ◽  
M.R. Leotta ◽  
O. Marcello ◽  
C. Zuliani
1997 ◽  
Vol 35 (2) ◽  
pp. 183-185 ◽  
Author(s):  
H. Moriuchi ◽  
M. Moriuchi ◽  
C.-C. J. Sun ◽  
M. Trucksis

1974 ◽  
Vol 110 (5) ◽  
pp. 771-772 ◽  
Author(s):  
M. Jarratt

2020 ◽  
Vol 72 (2) ◽  
Author(s):  
Marco Rossi ◽  
Paolo Siani ◽  
Adriano Grossi ◽  
Novella Carannante ◽  
Giovanni Di Caprio ◽  
...  

Author(s):  
Richard Pettigrew

Pettigrew focuses on trade-off objections to epistemic consequentialism. Such objections are similar to familiar objections from ethics where an intuitively wrong action (e.g., killing a healthy patient) leads to a net gain in value (e.g., saving five other patients). The objection to the epistemic consequentialist concerns cases where adopting an intuitively wrong belief leads to a net gain in epistemic value. Pettigrew defends the epistemic consequentialist against such objections by accepting that the unintuitive verdicts of consequentialism are unintuitive, but offering an error theory for why these intuitions do not show the view to be false.


2021 ◽  
Vol 13 (1) ◽  
pp. 233-238
Author(s):  
Seyed Mohammad Mousavi Mirzaei ◽  
Zahra Ahmadi

Drug-induced aseptic meningitis (DIAM) is a rare complication of certain drugs, most commonly reported with ibuprofen use. The present study reports on a male adolescent with intracranial hypertension and visual impairment accompanied by DIAM. We present a 16-year-old male patient who after ibuprofen consumption displayed headache, fever, photophobia, and blurred vision following heavy exercises. Examination of cerebrospinal fluid showed a mononuclear pleocytosis and an increase in protein concentration. Other examinations had normal results. The development of common clinical signs following ibuprofen use reflected DIAM. The patient’s vision was found to improve with supportive care and stopping of the drug during follow-up. Given the widespread use of nonsteroidal anti-inflammatory drugs and the fact that these drugs are the most common cause of DIAM, the probability of occurrence of this event should be always kept in mind, and screening for autoimmune diseases in these patients is of great importance.


2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S239-S239
Author(s):  
Arunmozhi S Aravagiri ◽  
Scott Kubomoto ◽  
Ayutyanont Napatkamon ◽  
Sarah Wilson ◽  
Sudhakar Mallela

Abstract Background Aseptic meningitis can be caused by an array of microorganisms, both bacterial and non-bacterial, as well as non-infectious conditions. Some etiologies of aseptic meningitis require treatment with antibiotics, antiviral, antifungals, anti-parasitic agents, immunosuppressants, and or chemotherapy. There are limited diagnostic tools for diagnosing certain types of aseptic meningitis, therefore knowing the differential causes of aseptic meningitis, and their relative percentages may assist in diagnosis. Review of the literature reveals that there are no recent studies of etiologies of aseptic meningitis in the United States (US). This is an epidemiologic study to delineate etiologies of aseptic meningitis in a large database of 185 HCA hospitals across the US. Methods Data was collected from January 2016 to December 2019 on all patients diagnosed with meningitis. CSF PCR studies, and CSF antibody tests were then selected for inclusion. Results Total number of encounters were 3,149 hospitalizations. Total number of individual labs analyzed was 10,613, and of these 262 etiologies were identified. 23.6% (62) of cases were due to enterovirus, 18.7% (49) due to HSV-2, 14.5% (38) due to West Nile virus, 13.7% (36) due to Varicella zoster (VZV), 10.5% (27) due to Cryptococcus. Additionally, we analyzed the rate of positive test results by region. Nationally, 9.7% of tests ordered for enterovirus were positive. In contrast, 0.5% of tests ordered for HSV 1 were positive. The southeastern United States had the highest rate of positive tests for HSV 2 (7% of tests ordered for HSV 2 were positive). The central United States had the highest rate of positive test for West Nile virus (11% of tests ordered for West Nile were positive). The northeastern region and the highest rate of positive tests for varicella zoster (18%). Table 1: Percentage of positive CSF tests (positive tests/tests ordered) Table 2: Lists the number of HIV patients and transplant patients that had positive CSF PCR/serologies Figure 1: Percentage of positive CSF tests in each region Conclusion Approximately 40% of aseptic meningitis population had treatable etiologies. A third of the Cryptococcus meningitis population had HIV. Furthermore, enteroviruses had the majority of cases within the US, which are similar to studies done in other parts of the world. Disclosures All Authors: No reported disclosures


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