Takayasu's Arteritis Coexisting with Wegener's Granulomatosis in a Teenager with Renal Insufficiency: Case Report

1999 ◽  
Vol 2 (4) ◽  
pp. 385-388 ◽  
Author(s):  
Carmen Mejia-Hernandez ◽  
Antonio Alvarez-Mendoza ◽  
Beatriz DeLeon-Bojorge

A case of Wegener's granulomatosis (WG) coexisting with Takayasu's arteritis (TA) in a 12-year-old girl is presented. She presented with fulminant and severe renal insufficiency due to crescentic glomerulonephritis. At autopsy, aortic lesions of Takayasu's arteritis coexisted with pulmonary and renal findings of WG, and the patient's serum at autopsy had an elevated level of antineutrophil cytoplasmic antibodies (ANCA). Both forms of vasculitis have been thought to be triggered by infectious agents and it is postulated that this occurrence accounts for the coexistence of the two forms of vasculitis in this case.

1998 ◽  
Vol 23 (12) ◽  
pp. 859-860 ◽  
Author(s):  
HITOYA OHTA ◽  
SHINICHI SHIRAI ◽  
KAORI NASU ◽  
MASAHIKO TEI ◽  
HIROFUMI KAMBARA ◽  
...  

2005 ◽  
Vol 119 (9) ◽  
pp. 746-749 ◽  
Author(s):  
G L Jones ◽  
A D Lukaris ◽  
H V Prabhu ◽  
M J K M Brown ◽  
J Bondeson

We present the case of a previously healthy 59-year-old man who was under treatment for scleritis and episcleritis when he developed a parotid-gland swelling and pus-producing sinus. On surgical exploration, the features were those of a parotid abscess, but the lesion not only failed to heal post-operatively but increased in size very significantly. There was also severe necrotizing keratitis of the eyes. Due to clinical suspicion and a positive antineutrophil cytoplasmic antibodies test, Wegener’s granulomatosis was diagnosed and the patient successfully treated with cyclophosphamide and steroids. Previously, a number of cases of Wegener’s granulomatosis causing salivary-gland swelling have been reported in the literature; this is the first case in which the disease has masqueraded as a parotid abscess.


2002 ◽  
Vol 10 (3) ◽  
pp. 277-279 ◽  
Author(s):  
Paul Schneider ◽  
Jörn Gröne ◽  
Jürgen Braun ◽  
Alejandra Perez-Canto ◽  
Heinz J Buhr

A patient with pansinusitis, nasal septum necrosis, and saddle nose deformity showed necrosis of the left mainstem, upper, and lower bronchi, with complete loss of left lung perfusion and ventilation. Pneumonectomy was performed. Histological findings showed extensive necrotizing and granulomatous bronchial inflammation with vasculitis of the bronchial arteries and the pulmonary vein. Wegener's granulomatosis was diagnosed, despite a negative cytoplasmic pattern of antineutrophil cytoplasmic antibodies and the lack of renal involvement.


1987 ◽  
Vol 30 (4) ◽  
pp. 451-454 ◽  
Author(s):  
David B. Hellmann ◽  
Kenneth Hardy ◽  
Stan Lindenfeld ◽  
Ernest Ring

Angiology ◽  
1998 ◽  
Vol 49 (1) ◽  
pp. 75-78 ◽  
Author(s):  
Masataka Iwane ◽  
Yasuko Nakamura ◽  
Ichiro Nishio ◽  
Mikio Arita

2010 ◽  
Vol 2 (01) ◽  
pp. 042-043 ◽  
Author(s):  
Seema Chhabra ◽  
Ranjana Walker Minz ◽  
Lekha Goyal ◽  
Nidhi Sharma

ABSTRACTWe report here two rare cases of myeloperoxidase–antineutrophil cytoplasmic antibody (MPO-ANCA)-positive Wegener’s granulomatosis (limited variant) which deceptively produced a cytoplasmic (C-ANCA) pattern on indirect immunofluorescence.


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