Long-term dentoskeletal side effects of mandibular advancement therapy in patients with obstructive sleep apnea: data from the Pays de la Loire sleep cohort

2021 ◽  
Author(s):  
Nicolas Baldini ◽  
Frédéric Gagnadoux ◽  
Wojciech Trzepizur ◽  
Nicole Meslier ◽  
Julien Dugas ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Side Effects ◽  
Mandibular Advancement ◽  
Obstructive Sleep

scholarly journals Side effects of mandibular advancement splints for the treatment of snoring and obstructive sleep apnea: a systematic review

2018 ◽  
Vol 23 (4) ◽  
pp. 45-54 ◽  
Author(s):  
Olivia de Freitas Mendes Martins ◽  
Cauby Maia Chaves Junior ◽  
Rowdley Robert Pereira Rossi ◽  
Paulo Afonso Cunali ◽  
Cibele Dal-Fabbro ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Side Effects ◽  
Oral Appliance ◽  
Risk Of Bias ◽  
Mandibular Advancement ◽  
Mandibular Advancement Splint ◽  
Obstructive Sleep ◽  
Craniofacial Complex

ABSTRACT Introduction: Occlusal side effects or development of pain and/or functional impairment of the temporomandibular complex are potential reasons for poor compliance or abandonment of mandibular advancement splints treatment for snoring and obstructive sleep apnea. Objective: This study aimed at providing a comprehensive review evaluating the craniofacial side effects of oral appliance therapy for snoring and obstructive sleep apnea. Methods: An electronic search was systematically conducted in PubMed and Virtual Health Library from their inception until October 2016. Only Randomized Controlled Trials whose primary aim was to measure objectively identified side effects on craniofacial complex of a custom-made oral appliance for treating primary snoring or obstructive sleep apnea were included. Studied patients should be aged 20 or older. The risk of bias in the trials was assessed in accordance with the recommendations of The Cochrane Risk of Bias criteria. Results: A total of 62 full-text articles were assessed for eligibility. After the review process, only 6 met all the inclusion criteria. All studies were rated as having a high risk of bias. The most uniformly reported mandibular advancement splint side effects were predominantly of dental nature and included a decrease in overjet and overbite. The risk of developing pain and function impairment of the temporomandibular complex appeared limited with long-term mandibular advancement splint use. Conclusion: The limited available evidence suggests that mandibular advancement splint therapy for snoring and obstructive sleep apnea results in changes in craniofacial morphology that are predominantly dental in nature, specially on a long-term basis. Considering the chronic nature of obstructive sleep apnea and that oral appliance use might be a lifelong treatment, a thorough customized follow-up should therefore be undertaken to detect possible side effects on craniofacial complex. It is also important to provide adequate information to the patients regarding these possible changes, especially to those in whom larger occlusal changes are to be expected or in whom they are unfavorable. Long-term assessments of adverse effects of oral appliance therapy, with larger study samples and recruitment of homogenous patient population are still required.

scholarly journals Long-term obstructive sleep apnea therapy: a 10-year follow-up of mandibular advancement device and continuous positive airway pressure

2020 ◽  
Vol 16 (3) ◽  
pp. 353-359 ◽  
Author(s):  
Julia A. M. Uniken Venema ◽  
Michiel H. J. Doff ◽  
Dilyana Joffe-Sokolova ◽  
Peter J. Wijkstra ◽  
Johannes H. van der Hoeven ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Continuous Positive Airway Pressure ◽  
Airway Pressure ◽  
Positive Airway Pressure ◽  
Mandibular Advancement Device ◽  
Mandibular Advancement ◽  
Obstructive Sleep

Long-term oral appliance therapy in obstructive sleep apnea syndrome: a controlled study on temporomandibular side effects

2011 ◽  
Vol 16 (3) ◽  
pp. 689-697 ◽  
Author(s):  
Michiel H. J. Doff ◽  
Steffanie K. B. Veldhuis ◽  
Aarnoud Hoekema ◽  
James J. R. Huddleston Slater ◽  
P. J. Wijkstra ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Side Effects ◽  
Sleep Apnea Syndrome ◽  
Oral Appliance ◽  
Controlled Study ◽  
Oral Appliance Therapy ◽  
Obstructive Sleep ◽  
Apnea Syndrome

scholarly journals The Most Effective Amount of Forward Movement for Oral Appliances for Obstructive Sleep Apnea: A Systematic Review

2019 ◽  
Vol 16 (18) ◽  
pp. 3248 ◽  
Author(s):  
Yuki Sakamoto ◽  
Akifumi Furuhashi ◽  
Eri Komori ◽  
Hiroyuki Ishiyama ◽  
Daichi Hasebe ◽  
...  
Keyword(s):  
Systematic Review ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Side Effects ◽  
Sleep Stage ◽  
Mandibular Advancement ◽  
Apnea Hypopnea Index ◽  
Oral Appliances ◽  
Forward Movement ◽  
Obstructive Sleep

This systematic review clarifies the amount of effective protrusion in mandibular advancement devices of oral appliances required for obstructive sleep apnea (OSA). The systematic review adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Review Manager 5 and GRADEpro were used to combine trials and analyze data. The present review included three studies. In mild to moderate OSA cases, measured using the apnea–hypopnea index (AHI), 50% protrusion was more effective than 75% protrusion. However, 75% protrusion was more effective for severe cases. Sleep stage, Epworth Sleepiness Scale (ESS), snoring index, and side effects significantly differed between the groups. Additionally, 75% protrusion was more effective (AHI: 0.38, 95% CI: −0.89 to 1.65, p = 0.56; sleep stage 3: −1.20, 95% CI: 9.54–7.14, p = 0.78; ESS: 1.07, 95% CI: −0.09 to 2.24, p = 0.07; snoring index: 0.09, 95% CI: 0.05–0.13, p < 0.05; side effects: RR: 1.89, 95% CI: 0.36–9.92, p = 0.45). As per the AHI, 75% protrusion was effective in severe cases, whereas 50% protrusion was effective in moderate cases. Analysis of different surrogate outcomes indicated that 75% protrusion was more effective. Further, well-designed, larger trials should determine the benefits for patients. Additionally, investigations of adherence and side effects with long-term follow-up are needed.

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