Catalytic hydrolysis of DNA by metal ions and complexes

2001 ◽  
Vol 6 (4) ◽  
pp. 337-347 ◽  
Author(s):  
Alavattam Sreedhara ◽  
J. A. Cowan
Keyword(s):  
Metal Ions ◽  
Catalytic Hydrolysis ◽  
Hydrolysis Of ◽  
Hydrolysis Of Dna

Cell-penetrating autoantibody induces caspase-mediated apoptosis through catalytic hydrolysis of DNA

2007 ◽  
Vol 15 (5) ◽  
pp. 2016-2023 ◽  
Author(s):  
Eun-Jung Lee ◽  
Eun-Jung Jang ◽  
Eunhae Lee ◽  
Jaehoon Yu ◽  
Hee Yong Chung ◽  
...  
Keyword(s):  
Catalytic Hydrolysis ◽  
Cell Penetrating ◽  
Hydrolysis Of ◽  
Hydrolysis Of Dna

Metalated carbon nitrides as base catalysts for efficient catalytic hydrolysis of carbonyl sulfide

2019 ◽  
Vol 55 (75) ◽  
pp. 11259-11262 ◽  
Author(s):  
Fangsong Guo ◽  
Shanrong Li ◽  
Yidong Hou ◽  
Junkang Xu ◽  
Sen Lin ◽  
...  
Keyword(s):  
Low Temperature ◽  
Alkali Metal ◽  
Metal Ions ◽  
Carbonyl Sulfide ◽  
Alkali Metal Ions ◽  
Catalytic Hydrolysis ◽  
Base Catalysts ◽  
Carbon Nitrides ◽  
Hydrolysis Of

Metalated carbon nitrides were designed and prepared by metalation of carbon nitrides with alkali metal ions, and the metalated carbon nitrides with potassium act as efficient base catalysts for hydrolysis of COS at low temperature.

The recognition and catalytic hydrolysis of ATP by protonated phenanthroline-bridged polyamine and (or) Ca(II), Mg(II), Zn(II), and La(III) ions

2004 ◽  
Vol 82 (4) ◽  
pp. 504-512 ◽  
Author(s):  
Yan-He Guo ◽  
Qing-Chun Ge ◽  
Hai Lin ◽  
Hua-Kuan Lin ◽  
Shou-Rong Zhu
Keyword(s):  
Metal Ions ◽  
Metal Ion ◽  
Atp Hydrolysis ◽  
Amino Nitrogen ◽  
Supramolecular Interactions ◽  
Hydrolysis Rate ◽  
Catalytic Hydrolysis ◽  
Mixed Ligands ◽  
Hydrolysis Of ◽  
Protonated Ligand

The supramolecular interactions of 2,9-di(((2′-phenylamino)ethyleneamino)methyl)-1,10-phenanthroline (L) and (or) metal ions (M = Ca2+, Mg2+, Zn2+, or La3+) with nucleotides were investigated. Furthermore, the hydrolysis of ATP catalyzed by a protonated ligand and (or) a metal ion (M = Ca2+, Mg2+, Zn2+, or La3+) was studied at pH 7.6 using 31P NMR spectra. Kinetics studies show that at pH 7.6 the protonated ligand, with a rate constant of 2.9 × 10–4 min–1, does not significantly promote ATP hydrolysis. However, in the presence of Ca2+, Mg2+, Zn2+, or La3+ ions, L can accelerate the hydrolysis of ATP, with corresponding rate constants of 5.73, 1.48, 6.76, and 31.7 × 10–3 min–1, respectively, which are about 29-, 7.5-, 34-, and 159-fold faster than the hydrolysis rate of free ATP. By comparison with M–ATP (M = Ca2+, Mg2+, and La3+) systems, the rates of M–L–ATP were also promoted. This has been achieved through the effective recognition of ATP and the availability of a good intramolecular nucleophile, i.e., a free amino nitrogen atom of L. Compared with the Zn2+–ATP system, the decrease in the rate of the Zn2+–L–ATP system at pH 7.6 may be attributed to the competition between the mixed ligands in binding Zn2+. Similar to L–ATP, the hydrolysis reactions in the Zn2+–L–ATP or M–L–ATP (M = Ca2+, Mg2+, and La3+) systems occur through an addition–elimination type mechanism, in which phosphoramidate intermediates were observed at 2.88 and 4.06 parts per million (ppm) in the L–ATP and Mg2+–L–ATP systems, respectively. Here, metal ions add control or regulation to the hydrolysis reaction. Key words: recognition, ATP hydrolysis, metal ions, phenanthroline-bridged polyamine.

Hydrolysis of 5′,5′-Tri- or Tetraphosphate-mRNA 5′-cap Analogs Promoted by Cu2+or Zn2+Metal Ions

2011 ◽  
Vol 30 (2) ◽  
pp. 135-148 ◽  
Author(s):  
Alicja Stachelska-Wierzchowska ◽  
Zbigniew J. Wieczorek
Keyword(s):  
Metal Ions ◽  
Hydrolysis Of

scholarly journals Catalytic hydrolysis of s-triazine compounds over Al2O3

1996 ◽  
Vol 27 (1-2) ◽  
pp. 167-173 ◽  
Author(s):  
Zhaoqi Zhan ◽  
Martin Müllner ◽  
Johannes A. Lercher
Keyword(s):  
Catalytic Hydrolysis ◽  
Hydrolysis Of
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