Characterisation of G serotype dependent non-antibody inhibitors of rotavirus in normal mouse serum

1998 ◽  
Vol 143 (7) ◽  
pp. 1277-1294 ◽  
Author(s):  
B. Beisner ◽  
D. Kool ◽  
A. Marich ◽  
I. H. Holmes
Keyword(s):  
Normal Mouse ◽  
Mouse Serum ◽  
Normal Mouse Serum

Low-molecular-weight Ia antigens in normal mouse serum

1976 ◽  
Vol 3 (1) ◽  
pp. 455-463 ◽  
Author(s):  
Christopher R. Parish ◽  
David C. Jackson ◽  
Ian F. C. McKenzie
Keyword(s):  
Molecular Weight ◽  
Normal Mouse ◽  
Mouse Serum ◽  
Low Molecular Weight ◽  
Normal Mouse Serum ◽  
Ia Antigens

Further characterization of the oncornavirus inactivating factor in normal mouse serum

Virology ◽  
1979 ◽  
Vol 98 (1) ◽  
pp. 20-34 ◽  
Author(s):  
Ronald C. Montelaro ◽  
Peter J. Fischinger ◽  
Susan B. Larrick ◽  
Nancy M. Dunlop ◽  
James N. Ihle ◽  
...  
Keyword(s):  
Normal Mouse ◽  
Mouse Serum ◽  
Normal Mouse Serum

Normal mouse serum-derived factor(s) which inhibits growth of the interleukin-2-dependent cell line CTLL

2009 ◽  
Vol 49 (1) ◽  
pp. 36-45 ◽  
Author(s):  
Christer Lindqvist ◽  
Carol Dahl ◽  
Carita Back ◽  
Christian Oker-Blom ◽  
Karl Akerman ◽  
...  
Keyword(s):  
Cell Line ◽  
Normal Mouse ◽  
Interleukin 2 ◽  
Mouse Serum ◽  
Normal Mouse Serum ◽  
Dependent Cell

Immunological adjuvants. I. The induction of soluble factor(s) by Freund's complete adjuvant

1974 ◽  
Vol 20 (4) ◽  
pp. 535-544 ◽  
Author(s):  
K. B. Orr ◽  
F. Paraskevas
Keyword(s):  
Normal Mouse ◽  
Mouse Serum ◽  
Soluble Antigen ◽  
Soluble Factor ◽  
Spleen Cells ◽  
Human Fibrinogen ◽  
Normal Mouse Serum ◽  
Freund’S Complete Adjuvant ◽  
Freund's Complete Adjuvant ◽  
Subsequent Addition

Serum collected from BALB/c mice 6 h after the intraperitoneal injection of Freund's complete adjuvant when mixed with a soluble antigen such as bovine serum albumin or human fibrinogen forms a cytophilic Ig which is taken up by the normal mouse spleen cells. When the serum was absorbed with an aggregated form of antigen, subsequent addition of soluble antigen failed to induce formation of cytophilic Ig, but an eluate recovered from the aggregated antigen did.This property of the serum is most likely non-specific since any antigen thus far tested is effective in inducing formation of cytophilic Ig and furthermore, absorption with one kind of antigen abolished the ability of the serum to form cytophilic Ig upon subsequent addition of any other antigen. Upon fractionation of the serum on Sephadex G-200 the activity was recovered in the 7-S fraction. However, the 4-S fraction (which lacks Ig) contained a factor which in the presence of antigen and normal mouse serum or its 7-S fraction formed a cytophilic Ig. The existing evidence indicated that the cytophilic Ig was taken up by 25 to 35% of the T cells (θ positive). Furthermore, about 15% of Ig carrying cells also took up the cytophilic Ig.The cytophilic Ig belongs to the IgG (IgG2a) class and presumptive evidence suggested that it may represent a complex of Ig and antigen.

Inhibition of chondrogenesis by normal mouse serum in cultured chick limb cells

1980 ◽  
Vol 130 (1) ◽  
pp. 21-30 ◽  
Author(s):  
Curtis L. Parker ◽  
Douglas F. Paulsen ◽  
Joseph A. Rosebrock ◽  
W.Craig Hooper
Keyword(s):  
Normal Mouse ◽  
Mouse Serum ◽  
Normal Mouse Serum

Indirect plaque-forming cells detected by use of normal mouse serum

1978 ◽  
Vol 38 (1) ◽  
pp. 124-130 ◽  
Author(s):  
Hans van Dijk ◽  
Charles G. van Bohemen
Keyword(s):  
Normal Mouse ◽  
Mouse Serum ◽  
Normal Mouse Serum

Taenia crassiceps surface immunoglobulins: parasite- or host-derived?

Parasitology ◽  
1990 ◽  
Vol 101 (1) ◽  
pp. 127-137 ◽  
Author(s):  
D. P. McManus ◽  
S. Lamsam
Keyword(s):  
Immune Response ◽  
Normal Mouse ◽  
Mouse Serum ◽  
Host Proteins ◽  
Taenia Crassiceps ◽  
Normal Mouse Serum ◽  
Specific Host ◽  
Surface Immunoglobulins ◽  
Survival And Development

SUMMARYIn common with other taeniid cestodes, host or host-like proteins, especially immunoglobulins, occur on the surface and in the cyst fluid of Taenia crassiceps metacestodes. Here, several approaches have been used to determine the origin of the immunoglobulins present on the tegument. Indirect IFAT showed that IgG was almost totally lost from the surface of bladders after 6 days culture in vitro. There was a rapid reacquisition of immunoglobulins following incubation of the cultured metacestodes with either normal mouse serum or mouse anti-T. crassiceps antiserum. Immunoprecipitation of in vitro translation products and biosynthetically labelled T. crassiceps proteins with a panel of anti-IgG antisera failed to positively identify any molecule with homology to mammalian immunoglobulins. These results suggest strongly that the immunoglobulins located on the surface of T. crassiceps are of host rather than parasite origin. The occurrence of a relatively low abundance receptor in the surface of the bladders, which binds non-specific host immunoglobulin, together with surface-bound specific anti-T. crassiceps antibodies can account for the presence of these host proteins. Freshly obtained bladders and metacestodes cultured in vitro for 6 days were transplanted into naive mice and the survival and development of the resulting parasites compared. In some individual mice there was a decrease in the number and volume of metacestodes and an increase in encapsulated parasites arising from cultured bladders. This was probably not related to the loss of host immunoglobulins from the parasite surface during culture as the reacquisition of these proteins after transplantation is likely to be far more rapid than any immune response could evoke in a naive host.

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