Paraoxonase polymorphisms, pesticide exposure and Parkinson's disease in a Caucasian population

2000 ◽  
Vol 107 (8-9) ◽  
pp. 979-983 ◽  
Author(s):  
M. C. Taylor ◽  
D. G. Le Couteur ◽  
G. D. Mellick ◽  
P. G. Board
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Pesticide Exposure ◽  
Caucasian Population

scholarly journals Chronic systemic pesticide exposure reproduces features of Parkinson's disease

10.1038/81834 ◽  
2000 ◽  
Vol 3 (12) ◽  
pp. 1301-1306 ◽  
Author(s):  
Ranjita Betarbet ◽  
Todd B. Sherer ◽  
Gillian MacKenzie ◽  
Monica Garcia-Osuna ◽  
Alexander V. Panov ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Pesticide Exposure ◽  
Systemic Pesticide

The HhaI polymorphism in the CYP2D6 gene is not associated with Parkinson's disease in a Caucasian population

1995 ◽  
Vol 2 (6) ◽  
pp. 580-582 ◽  
Author(s):  
D.J. Nicholl ◽  
P. Bennett ◽  
D.B. Ramsden ◽  
S.L. Ho ◽  
A.C. Williams
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Caucasian Population ◽  
Cyp2d6 Gene

scholarly journals Platelet mitochondrial activity and pesticide exposure in early Parkinson's disease

2015 ◽  
Vol 30 (6) ◽  
pp. 862-866 ◽  
Author(s):  
Jeff M. Bronstein ◽  
Kimberly Paul ◽  
Laurice Yang ◽  
Richard H. Haas ◽  
Clifford W. Shults ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Pesticide Exposure ◽  
Mitochondrial Activity ◽  
Early Parkinson’S Disease

Pesticide exposure on southwestern Taiwanese with MnSOD and NQO1 polymorphisms is associated with increased risk of Parkinson's disease

2007 ◽  
Vol 378 (1-2) ◽  
pp. 136-141 ◽  
Author(s):  
Chin-Shih Fong ◽  
Ruey-Meei Wu ◽  
Jia-Ching Shieh ◽  
Ya-Ting Chao ◽  
Yi-Ping Fu ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Pesticide Exposure ◽  
Increased Risk

scholarly journals Editor’s Highlight: Base Excision Repair Variants and Pesticide Exposure Increase Parkinson’s Disease Risk

2017 ◽  
Vol 158 (1) ◽  
pp. 188-198 ◽  
Author(s):  
Laurie H. Sanders ◽  
Kimberly C. Paul ◽  
Evan H. Howlett ◽  
Hakeem Lawal ◽  
Sridhar Boppana ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Base Excision Repair ◽  
Pesticide Exposure ◽  
Disease Risk ◽  
Excision Repair ◽  
Base Excision

scholarly journals Parkinson’s disease hospitalization rates and pesticide use in urban and non-urban regions of Brazil

2021 ◽  
Author(s):  
Aline de Souza Espindola Santos ◽  
Noa Krawczyk ◽  
Christine Gibson Parks ◽  
Carmen Froes Ildes Asmus ◽  
Volney de Magalhães Câmara ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Urban Areas ◽  
Pesticide Exposure ◽  
Pesticide Use ◽  
Moderate Correlation ◽  
Correlation Test ◽  
Hospitalization Rates ◽  
Per Capita ◽  
Spearman’S Correlation

Abstract Background Few studies have evaluated the role played by pesticide exposure in the development of Parkinson’s disease (PD) in Brazil. Objective This study aimed to investigate the association between pesticide use and PD hospitalization in Brazilian micro-regions. Method Pesticide expenditure per capita in 1985 and PD hospitalization rates (HR) from 1997 to 2007 were calculated for all 552 Brazilian micro-regions. The Spearman's correlation test was used to compare pesticide expenditure and PD HR by sex, age, and urban and non-urban micro-regions. Micro-regions were grouped according to the quintiles of pesticide expenditure. PD HR ratios (HRR) were calculated to compare PD HR across the quintiles of pesticide expenditure. Results Moderate correlation (r=0.518; p<0.001) between PD HR in non-urban micro-regions and pesticide expenditure was observed. In non-urban areas, compared with micro-regions of the first quintile of pesticide use, PD HRR ranged from 1.70 to 5.90 in micro-regions of higher pesticide use. In general, regardless of sex and age, the higher the use of pesticides, the greater the magnitude of PD HRR. Conclusion Our results suggest that pesticide use is associated with PD in Brazil, especially in non-urban areas where pesticides are used more intensively.

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