Cell-Extracellular Matrix Interaction in Glioma Invasion

1999 ◽  
Vol 141 (3) ◽  
pp. 295-305 ◽  
Author(s):  
R. H. Goldbrunner ◽  
J. J. Bernstein ◽  
J.-C. Tonn
Keyword(s):  
Extracellular Matrix ◽  
Glioma Invasion ◽  
Matrix Interaction

Building Protein‐Protein and Protein‐Glycosaminoglycan Interaction Networks Using MatrixDB, the Extracellular Matrix Interaction Database

2021 ◽  
Vol 1 (4) ◽  
Author(s):  
Coline Berthollier ◽  
Sylvain D. Vallet ◽  
Madeline Deniaud ◽  
Olivier Clerc ◽  
Sylvie Ricard‐Blum
Keyword(s):  
Extracellular Matrix ◽  
Interaction Networks ◽  
Matrix Interaction ◽  
Interaction Database

Human decidual and placental relaxins

1991 ◽  
Vol 3 (4) ◽  
pp. 385 ◽  
Author(s):  
GD Bryant-Greenwood
Keyword(s):  
Extracellular Matrix ◽  
Corpus Luteum ◽  
Human Placenta ◽  
Northern Analysis ◽  
Fetal Membranes ◽  
Decidual Cell ◽  
Matrix Interaction ◽  
Polypeptide Hormones ◽  
Collagen Remodelling

The human placenta and decidua are intrauterine production sites for a range of polypeptide hormones. Relaxin is one of these hormones, its production having been demonstrated by immunocytochemistry and Northern analysis. There are two relaxin genes in the human genome, termed H1 and H2; only the latter is expressed in cyclic and pregnant corpus luteum. However, it has recently been shown that both genes are expressed in the decidua and placenta. It is not known whether both are translated. These hormone(s) may act in a paracrine fashion and be partly responsible for the control of enzymes and inhibitors involved in collagen remodelling in the fetal membranes in the last weeks of pregnancy. An autocrine role of decidual relaxin and a possible decidual-cell/macrophage/extracellular-matrix interaction is described; this may act as a unit in the elaboration of a range of hormones.

Effects of Titanium Surface Topography on the Cell-Extracellular Matrix Interaction in Osteoblasts

2003 ◽  
Vol 426-432 ◽  
pp. 3023-3030 ◽  
Author(s):  
Barbara Nebe ◽  
Frank Lüthen ◽  
Axel Baumann ◽  
Ulrich Beck ◽  
Annette Diener ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Surface Topography ◽  
Titanium Surface ◽  
Matrix Interaction

Localization of Transforming Growth Factor-β- Expressing Cells and Comparison with Major Extracellular Components in Aural Cholesteatoma

1997 ◽  
Vol 106 (8) ◽  
pp. 669-673 ◽  
Author(s):  
Stephan Lang ◽  
Volker Schilling ◽  
Brigitte Mack ◽  
Barbara Wollenberg ◽  
Andreas Nerlich
Keyword(s):  
Extracellular Matrix ◽  
Growth Factor ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β ◽  
Matrix Proteins ◽  
Matrix Interaction ◽  
Cell Matrix ◽  
Continuous Band ◽  
Enhanced Expression ◽  
Stimulation Of

Transforming growth factor-β (TGF-β) plays an important role in the regulation of extracellular matrix (ECM) deposition by stimulating the synthesis of individual matrix proteins like tenascin and fibronectin. Cholesteatoma shows significant changes in the ECM, supporting the view of adisturbed cell-matrix interaction. The purpose of our present study was to evaluate the distribution of TGF-β in comparison to the deposition of tenascin, fibronectin, and collagen as major components of the ECM in cholesteatoma (n = 12) by means of histochemistry and immunohistochemistry. We found TGF-P in lymphocytes and fibrohistiocytes in the stroma of 7 cholesteatomas. In corresponding sections, a marked expression of tenascin and fibronectin was seen manifesting as a continuous band along the epidermal-stromal junction, extending to the deeper stroma. In addition, in those cases of TGF-β expression, beginning collagen fibril formation was seen in adjacent deeper stroma layers, indicating beginning stromal fibrosis. These results suggest that TGF-β may be involved in the stimulation of the synthesis of tenascin, fibronectin, and collagen. Furthermore, the enhanced expression of tenascin and fibronectin provides evidence for a deregulated cell-matrix interaction in cholesteatoma associated with the enhanced proliferative process of cholesteatoma formation.

Loss of cell-extracellular matrix interaction triggers retinal regeneration accompanied byRaxandPax6Activation

genesis ◽  
2013 ◽  
Vol 51 (6) ◽  
pp. 410-419 ◽  
Author(s):  
Ayaka Nabeshima ◽  
Chisato Nishibayashi ◽  
Yoko Ueda ◽  
Hajime Ogino ◽  
Masasuke Araki
Keyword(s):  
Extracellular Matrix ◽  
Retinal Regeneration ◽  
Matrix Interaction

scholarly journals Down Regulation of NO Signaling in Trypanosoma cruzi upon Parasite-Extracellular Matrix Interaction: Changes in Protein Modification by Nitrosylation and Nitration

2015 ◽  
Vol 9 (4) ◽  
pp. e0003683 ◽  
Author(s):  
Milton Pereira ◽  
Chrislaine Soares ◽  
Gisele André Baptista Canuto ◽  
Marina Franco Maggi Tavares ◽  
Walter Colli ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Trypanosoma Cruzi ◽  
Protein Modification ◽  
Down Regulation ◽  
Matrix Interaction ◽  
No Signaling
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