Cerebral Blood Flow Velocity and Vasomotor Reactivity Before and after Shunting Surgery in Patients with Normal Pressure Hydrocephalus

1998 ◽  
Vol 140 (6) ◽  
pp. 599-605 ◽  
Author(s):  
E.-J. Lee ◽  
Y.-C. Hung ◽  
C.-H. Chang ◽  
M.-C. Pai ◽  
H.-H. Chen
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Flow Velocity ◽  
Normal Pressure Hydrocephalus ◽  
Blood Flow Velocity ◽  
Cerebral Blood Flow Velocity ◽  
Normal Pressure ◽  
Vasomotor Reactivity ◽  
Before And After

scholarly journals Effects of LI11 Acupuncture on CO2 reactivity in the anterior and middle cerebral arteries during hyperventilation-induced hypocapnia in normal subjects: A before and after study

2021 ◽  
Vol 42 (4) ◽  
pp. 174-185
Author(s):  
Gyeong-muk Kim ◽  
Woo-Sang Jung ◽  
Seungwon Kwon ◽  
Chul Jin ◽  
Seung-Yeon Cho ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Flow Velocity ◽  
Cerebral Artery ◽  
Blood Flow Velocity ◽  
Cerebral Blood Flow Velocity ◽  
Cerebral Arteries ◽  
Co2 Reactivity ◽  
Middle Cerebral Arteries ◽  
Before And After

Objectives: The LI11 (Quchi) acupuncture point has always been included in the Seven acupoints for stroke; however, additional LI11 acupuncture research is needed. In this study, the effect of LI11 acupuncture on cerebral blood flow of the anterior cerebral arteries (ACA) and middle cerebral arteries (MCA) was investigated.Method: This study included 10 healthy young male subjects. Cerebral blood flow velocity and cerebrovascular reactivity were measured using transcranial Doppler sonography. Changes in hyperventilation-induced carbon dioxide (CO2) reactivity and modified ACA and MCA blood flow velocity at 40 mmHg (CV40), blood pressure, and heart rate were observed before and after LI11 acupuncture treatment.Results: A statistically significant increase in contralateral anterior cerebral artery CO2 reactivity (p=0.036) and decrease in contralateral middle cerebral artery CV40 (p=0.047) were observed. No significant difference in mean blood pressure was shown. A statistically significant increase in heart rate occurred after LI11 acupuncture; however, it was not clinically significant as there were negligible changes in the heart rhythm.Conclusions: LI11 acupuncture treatment could improve cerebral blood flow velocity. These results might be explained by regulating endothelium-dependent vessel dilation in the anterior cerebral artery region.Trial registration: This trial has been registered with Clinical Research Information Service, a service of the Korea Centers for Disease Control and Prevention: KCT0004494 (retrospectively registered). https://cris.nih.go.kr/cris/search/search_result_st01.jsp?seq=15359

scholarly journals Cerebral Blood Flow Velocity and Vasomotor Reactivity During Autonomic Challenges in Heart Failure

2014 ◽  
Vol 63 (3) ◽  
pp. 194-202 ◽  
Author(s):  
Stacy L. Serber ◽  
Brenda Rinsky ◽  
Rajesh Kumar ◽  
Paul M. Macey ◽  
Gregg C. Fonarow ◽  
...  
Keyword(s):  
Heart Failure ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Flow Velocity ◽  
Blood Flow Velocity ◽  
Cerebral Blood Flow Velocity ◽  
Vasomotor Reactivity

Cerebral Blood Flow Velocity and Cognition in Children Before and After Adenotonsillectomy

PEDIATRICS ◽  
2008 ◽  
Vol 122 (1) ◽  
pp. 75-82 ◽  
Author(s):  
A. M. Hogan ◽  
C. M. Hill ◽  
D. Harrison ◽  
F. J. Kirkham
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Flow Velocity ◽  
Blood Flow Velocity ◽  
Cerebral Blood Flow Velocity ◽  
Before And After

Analysis of relative changes in pulse shapes of intracranial pressure and cerebral blood flow velocity during infusion test

2021 ◽  
Author(s):  
Arkadiusz Ziółkowski ◽  
Agata Pudełko ◽  
Agnieszka Kazimierska ◽  
Marek Czosnyka ◽  
Zofia Czosnyka ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Intracranial Pressure ◽  
Flow Velocity ◽  
Blood Flow Velocity ◽  
Cerebral Blood Flow Velocity ◽  
Normal Pressure ◽  
Infusion Test ◽  
Intracranial Compliance ◽  
Assessment Approach

Abstract Objective: Analysis of relative changes in the shapes of pulse waveform of intracranial pressure (ICP) and transcranial Doppler cerebral blood flow velocity (CBFV) may provide information on intracranial compliance. We tested this hypothesis, introducing an index named the Ratio of Pulse Slopes (RPS) that is based on inclinations of the ascending parts of ICP and CBFV pulse waveforms. It has hypothetically a simple interpretation: 1 – good compliance, the less than 1, reduced compliance. Here, we investigated the usefulness of RPS for intracranial compliance assessment. Approach: ICP and CBFV signals recorded simultaneously in 30 normal pressure hydrocephalus patients during infusion test were retrospectively analysed. CBFV was measured in the middle cerebral artery. Changes in RPS during the test were compared to changes in the height ratio of the first and second peak of ICP pulse (P1/P2) and the shape of ICP pulse classified from normal (1) to pathological (4). Values are medians (lower, upper quartiles). Main results: There was a significant correlation between baseline RPS and brain elasticity (R = -0.55, p=0.0018). During infusion test, both RPS and P1/P2 decreased with rising ICP (RPS: 0.80 (0.56, 0.92) vs. 0.63 (0.44, 0.80), p = 0.00015; P1/P2: 0.58 (0.50, 0.91) vs. 0.52 (0.36, 071), p=0.00009) while the ICP pulses became more pathological in shape (class: 3 (2, 3) vs. 3 (3, 4), p=0.04). The magnitude of decrease in RPS during infusion was inversely correlated with baseline P1/P2 (R= -0.40, p<0.03). Significance: During infusion, the slopes of ascending parts of ICP and CBFV pulses become increasingly divergent with a shift in opposite directions. RPS seems a promising methodological tool to monitor brain compliance with no additional volumetric manipulation required.

The Effect of Clonidine on Cerebral Blood Flow Velocity, Carbon Dioxide Cerebral Vasoreactivity, and Response to Increased Arterial Pressure in Human Volunteers

1997 ◽  
Vol 87 (3) ◽  
pp. 553-558 ◽  
Author(s):  
Hye-Won Lee ◽  
James E. Caldwell ◽  
Barbara Dodson ◽  
Pekka Talke ◽  
Joan Howley
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Arterial Pressure ◽  
Flow Velocity ◽  
Blood Flow Velocity ◽  
Doppler Ultrasonography ◽  
Cerebral Blood Flow Velocity ◽  
Human Volunteers ◽  
Before And After ◽  
Cerebral Vasoreactivity

Background Because patients may be taking clonidine chronically or may be receiving it as a premedication before surgery, the authors investigated its effect on cerebral hemodynamics. Methods In nine volunteers, middle cerebral artery mean blood flow velocity (Vm) was measured using transcranial Doppler ultrasonography (TCD). CO2 vasoreactivity was measured before clonidine administration (preclonidine), 90 min after clonidine, 5 microg/kg orally, then following restoration of mean arterial pressure (MAP) to the preclonidine level. In addition, Vm was measured after a phenylephrine-induced 30-mmHg increase in MAP. Results After clonidine administration, Vm decreased from 62 +/- 9 to 48 +/- 8 cm/s (P &lt; 0.01), and MAP decreased from 86 +/- 10 to 63 +/- 5 mmHg (P &lt; 0.01; mean +/- SD). Clonidine decreased the CO2 vasoreactivity slope from 2.2 +/- 0.4 to 1.2 +/- 0.5 cm x s(-1) x mmHg(-1) (P &lt; 0.05); restoring MAP to the preclonidine level increased the slope to 1.60 +/- 0.5 cm x s(-1) x mmHg(-1), still less than the preclonidine slope (P &lt; 0.05). CO2 vasoreactivity expressed as a percentage change in Vm, decreased after clonidine, 3.5 +/- 0.8 versus 2.4 +/- 0.8 %/mmHg (P &lt; 0.05); this difference disappeared after restoration of MAP, 3.1 +/- 1.2 %/mmHg. With a 30-mmHg increase in MAP, Vm increased by 13% before and after clonidine (P &lt; 0.05). Conclusions Clonidine, 5 microg/kg orally, decreases Vm and slightly attenuates cerebral CO2 vasoreactivity, therefore decreased cerebral blood flow and mildly attenuated CO2 vasoreactivity should be anticipated.

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